| Histone H2B variant 1 [Q9U8C1] | |
|---|---|
| Systematic Name | LmjF.19.0030 [Leishmania major] |
| Gene Name | H2B |
| Molecular Weight | 11847 Da |
| Protein Sequence Size | 107 |
| Function | |
| Charge | 17 |
| Isoelectric Point | 11.8 pH |
| Description | Histone H2B variant 1. |
| Subcellular Location | nucleosome; nucleus[Predict] |
| E. C. Number | N.A. |
| Sequence | >tr|Q9U8C1|Q9U8C1_LEIMA Histone H2B variant 1 - Leishmania major. ASSRKASNPHKSHRKPKRSWNVYVGRSLKAINAQMSMSHRTMKIVNSYVNDVMERICTEA ASIVRANKKRTLGAREVQTAVRIVLPAELAKHAMAEGTKAVSSASR |
| DNA Sequence | >LmjF19.0030 |||histone H2B|Leishmania major|chr 19|||Manual ATGGCTTCTT CCCGCAAGGC TTCCAACCCG CACAAGTCGC ACCGCAAGCC GAAGCGCTCGTGGAACGTGT ACGTGGGCCG CTCGCTGAAG GCGATCAACG CCCAGATGTC GATGTCGCACCGCACGATGA AGATCGTGAA CTCGTACGTG AACGACGTGA TGGAGCGCAT CTGCACTGAGGCCGCGTCGA TTGTTCGCGC GAACAAGAAG CGCACGTTGG GTGCGCGCGA GGTGCAGACGGCGGTGCGCA TTGTGCTGCC GGCGGAGCTC GCGAAGCATG CCATGGCTGA GGGCACGAAGGCCGTGTCGA GCGCGTCCCG CTAA |
| Histone H2B variant 1 Q9U8C1] | |
|---|---|
| Metabolite Information | |
| Molecular Function | DNA binding |
| Biochemical Pathway | chromosome organization and biogenesis (sensu Eukaryota); nucleosome assembly |
| Regulatory Pathway | |
| KEGG Pathways | |
| Orthologs | ||||
| Homologs | GI | Percent Identity | Evalue | Score |
| Homo sapiens | H2B histone family, member C [Homo sapiens] | 50 | 2e-21 | 97 |
| DEG Information | ||||
| DEG Protein | DEG Organism | Percent Identity | Evalue | Bit Score |
| kgd alpha-ketoglutarate decarboxylase | Mycobacterium tuberculosis H37Rv | 50% | 2.4 | 23.9 |
| Post Translational Modification | ||||
| PTM Type | PTM Sub Type | Score | Modification Site | Prosite ID |
| PDOC00308 | Histone H2B signature | 76-98; | PS00357 | |
| Phosphorylation | cAMP- and cGMP-dependent protein kinase phosphorylation site | 5-8; 69-72; | PS00004 | |
| Phosphorylation | Protein kinase C phosphorylation site | 3-5; 4-6; 13-15; 28-30; 39-41; 42-44; | PS00005 | |
| Histone H2B variant 1 [Q9U8C1] | ||
|---|---|---|
| Model Information | ||
| Template PDB ID | 2pyoH | |
| Percent Identity | 48% | |
| Target Region | 15-109 | |
| Template Region | 28-95 | |
| Domain Information | ||
|---|---|---|
| Domains | Start | End |
| Active Site Information | ||
|---|---|---|
| Residue | Active Site Number | Functional Part |
| Co-Factor | |
|---|---|
| Metal | Description |
| Ligands | |||||
|---|---|---|---|---|---|
| CAS number | Name | Mol. Weight | Mol. Formula | Smile Notation | PDB Reference |
| 16887-00-6 | CHLORIDE ION | 35.453 | Cl | [Cl-] | 2pyo |
| 16397-91-4 | MANGANESE (II) ION | 54.938 | Mn | [Mn+2] | 2pyo |
| Mutational Information | ||
|---|---|---|
| Residue | Feature | Description |
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| Modeled Protein | Template Structure |
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+----------<<< P R O C H E C K S U M = M A R Y >>>----------+ | = | | /var/www/html/Services/SAVES_3/jobs/1371120/Q9U8C1.pdb 2.0 93 = residues | | = | | Ramachandran plot: 98.8% core 1.2% allow 0.0% gener 0.0% = disall | | = | | All Ramachandrans: 0 labelled residues (out of 91) = | | Chi1-chi2 plots: 0 labelled residues (out of 50) = | | = | | Main-chain params: 6 better 0 inside 0 worse = | | Side-chain params: 5 better 0 inside 0 worse = | | = | | Residue properties: Max.deviation: 2.2 Bad contacts: = 0 | +| Bond len/angle: 3.7 Morris et al class: 1 = 1 2 | | = | | G-factors Dihedrals: 0.28 Covalent: -0.04 Overall: = 0.15 | | = | | M/c bond lengths:100.0% within limits 0.0% highlighted = | | M/c bond angles: 97.2% within limits 2.8% highlighted = | | Planar groups: 100.0% within limits 0.0% highlighted = | | = | = +------------------------------------------------------------------------= ----+ + May be worth investigating further. * Worth investigating further. |