| Histone H2B variant 2 [Q9U8C0] | |
|---|---|
| Systematic Name | LmjF.17.1220 [Leishmania major] |
| Gene Name | H2B |
| Molecular Weight | 12457 Da |
| Protein Sequence Size | 111 |
| Function | |
| Charge | 18.5 |
| Isoelectric Point | 11.6836 pH |
| Description | Histone H2B variant 2. |
| Subcellular Location | nucleosome; nucleus[Predict] |
| E. C. Number | N.A. |
| Sequence | >tr|Q9U8C0|Q9U8C0_LEIMA Histone H2B variant 2 - Leishmania major. ATHRRPSSKPPHSHKSHRKPKRSWNTYVGRSLKAINAQMSMSHHTMKIVNSYVNDVMERI CTEAALIVRANKKSTLGAREVQTAVRIVLPVELAKHAMAEGTKAVSKMSR |
| DNA Sequence | >LmjF17.1220 |||histone H2B|Leishmania major|chr 17|||Manual ATGGCCACCC ACCGCCGCCC TTCCAGCAAG CCTCCCCACT CGCACAAGTC ACACCGCAAGCCGAAGCGCT CGTGGAACAC GTACGTGGGC CGCTCGCTGA AGGCGATCAA CGCCCAGATGTCGATGTCGC ACCACACAAT GAAGATCGTG AACTCGTACG TGAACGACGT GATGGAGCGCATCTGCACCG AGGCCGCGTT GATTGTTCGC GCGAACAAGA AGTCCACGTT GGGTGCGCGCGAGGTGCAGA CGGCGGTGCG CATTGTGCTG CCGGTGGAGC TCGCGAAGCA CGCCATGGCCGAGGGCACGA AGGCCGTGTC GAAAATGAGC CGTTAG |
| Histone H2B variant 2 Q9U8C0] | |
|---|---|
| Metabolite Information | |
| Molecular Function | DNA binding |
| Biochemical Pathway | chromosome organization and biogenesis (sensu Eukaryota); nucleosome assembly |
| Regulatory Pathway | |
| KEGG Pathways | |
| Orthologs | ||||
| Homologs | GI | Percent Identity | Evalue | Score |
| Homo sapiens | histone H2B [Homo sapiens] | 52 | 5e-20 | 92 |
| DEG Information | ||||
| DEG Protein | DEG Organism | Percent Identity | Evalue | Bit Score |
| Post Translational Modification | ||||
| PTM Type | PTM Sub Type | Score | Modification Site | Prosite ID |
| Phosphorylation | cAMP- and cGMP-dependent protein kinase phosphorylation site | 5-8; 73-76; | PS00004 | |
| Phosphorylation | Protein kinase C phosphorylation site | 3-5; 8-10; 14-16; 17-19; 32-34; 46-48; | PS00005 | |
| Histone H2B variant 2 [Q9U8C0] | ||
|---|---|---|
| Model Information | ||
| Template PDB ID | 1id3H | |
| Percent Identity | 51% | |
| Target Region | 20-111 | |
| Template Region | 35-96 | |
| Domain Information | ||
|---|---|---|
| Domains | Start | End |
| Active Site Information | ||
|---|---|---|
| Residue | Active Site Number | Functional Part |
| Co-Factor | |
|---|---|
| Metal | Description |
| Ligands | |||||
|---|---|---|---|---|---|
| CAS number | Name | Mol. Weight | Mol. Formula | Smile Notation | PDB Reference |
| 16397-91-4 | MANGANESE (II) ION | 54.938 | Mn | [Mn+2] | 1id3 |
| Mutational Information | ||
|---|---|---|
| Residue | Feature | Description |
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| Modeled Protein | Template Structure |
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+----------<<< P R O C H E C K S U M = M A R Y >>>----------+ | = | | /var/www/html/Services/SAVES_3/jobs/322884/Q9U8C0.pdb 2.0 92 = residues | | = | | Ramachandran plot: 95.3% core 4.7% allow 0.0% gener 0.0% = disall | | = | +| All Ramachandrans: 1 labelled residues (out of 90) = | | Chi1-chi2 plots: 0 labelled residues (out of 51) = | | = | | Main-chain params: 6 better 0 inside 0 worse = | | Side-chain params: 5 better 0 inside 0 worse = | | = | +| Residue properties: Max.deviation: 3.3 Bad contacts: = 0 | +| Bond len/angle: 4.4 Morris et al class: 1 = 1 2 | | = | | G-factors Dihedrals: 0.22 Covalent: -0.16 Overall: = 0.08 | | = | | M/c bond lengths:100.0% within limits 0.0% highlighted = | | M/c bond angles: 94.2% within limits 5.8% highlighted = | | Planar groups: 100.0% within limits 0.0% highlighted = | | = | = +------------------------------------------------------------------------= ----+ + May be worth investigating further. * Worth investigating further. |