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Ubiquitin-conjugating enzyme E2 [Q9NED4]
Systematic NameLmjF.04.0680 [Leishmania major]
Gene NameP1105.09
Molecular Weight17050 Da
Protein Sequence Size148
Function
Charge3
Isoelectric Point8.4598 pH
DescriptionUbiquitin-conjugating enzyme E2.
Subcellular LocationN.A.[Predict]
E. C. Number 6.3.2.-
Sequence>tr|Q9NED4|Q9NED4_LEIMA Ubiquitin-conjugating enzyme E2 - Leishmania major.
LTTRIIKETEKLQKECPPGITATPTKENPRYFMVTIQGPPQSCYEGGLFRLELFLPEEYP
MKPPKVRFLTRIYHPNVDKVGRICLDIIKDKWSPALLINKVLLSIQILMSSPNPDDPLAN
DVAEHWKEDEASALQTAREWTRKYAKP
DNA Sequence>LmjF04.0680 |||ubiquitin-conjugating enzyme E2, putative|Leishmania major|chr 4|||Manual
ATGCTCACAA CACGTATTAT TAAGGAGACG GAGAAACTCC AGAAGGAGTG TCCGCCGGGCATCACGGCCA CACCCACCAA GGAGAACCCG CGCTACTTTA TGGTGACCAT CCAGGGGCCGCCGCAGTCGT GCTACGAGGG CGGCCTCTTC CGCCTGGAGC TGTTCCTGCC CGAGGAGTACCCGATGAAGC CGCCGAAGGT TCGCTTCCTC ACGCGTATCT ATCACCCCAA CGTAGACAAGGTGGGTCGCA TCTGTCTCGA CATCATCAAG GATAAGTGGT CGCCGGCGCT GCTCATCAACAAGGTGCTGC TATCTATCCA GATCCTCATG TCGAGCCCAA ACCCAGATGA TCCTCTGGCGAACGACGTCG CGGAGCACTG GAAGGAAGAC GAGGCCAGCG CGCTGCAGAC GGCCCGCGAGTGGACGCGCA AGTACGCCAA GCCGTGA
Ubiquitin-conjugating enzyme E2 Q9NED4]
Metabolite Information
Molecular Function
Biochemical Pathway
Regulatory Pathway
KEGG PathwaysK10580
Orthologs
Homologs GI Percent Identity Evalue Score
Homo sapiensubiquitin-conjugating enzyme E2N [Homo sapiens]708e-56212
DEG Information
DEG Protein DEG Organism Percent Identity Evalue Bit Score
YDL064w E2 ubiquitin-conjugating enzymeSaccharomyces cerevisiae31%1e-1886.3
Post Translational Modification
PTM Type PTM Sub Type Score Modification Site Prosite ID
PDOC00163Ubiquitin-conjugating enzymes signature and profile74-88; PS00183
PDOC00163Ubiquitin-conjugating enzymes signature and profile40.2334-136; -PS50127
PhosphorylationCasein kinase II phosphorylation site43-46; 137-140; PS00006
PhosphorylationProtein kinase C phosphorylation site3-5; 10-12; 137-139; 142-144; PS00005
Ubiquitin-conjugating enzyme E2 [Q9NED4]
Model Information
Template PDB ID2c2vK
Percent Identity70%
Target Region1-148
Template Region3-152
Domain Information
Domains Start End
Active Site Information
Residue Active Site Number Functional Part
Co-Factor
Metal Description
Ligands
CAS number Name Mol. Weight Mol. Formula Smile Notation PDB Reference
Mutational Information
Residue Feature Description
Modeled Protein Template Structure
+----------<<< P R O C H E C K S U M = M A R Y >>>----------+ | = | | /var/www/html/Services/SAVES_3/jobs/1466916/Q9NED4.pdb 2.0 148 = residues | | = | +| Ramachandran plot: 92.9% core 5.6% allow 1.6% gener 0.0% = disall | | = | +| All Ramachandrans: 2 labelled residues (out of 146) = | +| Chi1-chi2 plots: 1 labelled residues (out of 94) = | | = | | Main-chain params: 6 better 0 inside 0 worse = | | Side-chain params: 5 better 0 inside 0 worse = | | = | *| Residue properties: Max.deviation: 3.9 Bad contacts: = 3 | *| Bond len/angle: 9.4 Morris et al class: 1 = 1 2 | +| 2 cis-peptides = | | G-factors Dihedrals: -0.10 Covalent: -0.39 Overall: = -0.20 | | = | | M/c bond lengths: 97.5% within limits 2.5% highlighted = | *| M/c bond angles: 89.6% within limits 10.4% highlighted 1 off = graph | | Planar groups: 100.0% within limits 0.0% highlighted = | | = | = +------------------------------------------------------------------------= ----+ + May be worth investigating further. * Worth investigating further.
Overlapped Structure Procheck Summary
LeishBase: Leishmania Structural Database