Ubiquitin-conjugating enzyme E2 [Q9NED4] | |
---|---|
Systematic Name | LmjF.04.0680 [Leishmania major] |
Gene Name | P1105.09 |
Molecular Weight | 17050 Da |
Protein Sequence Size | 148 |
Function | |
Charge | 3 |
Isoelectric Point | 8.4598 pH |
Description | Ubiquitin-conjugating enzyme E2. |
Subcellular Location | N.A.[Predict] |
E. C. Number | 6.3.2.- |
Sequence | >tr|Q9NED4|Q9NED4_LEIMA Ubiquitin-conjugating enzyme E2 - Leishmania major. LTTRIIKETEKLQKECPPGITATPTKENPRYFMVTIQGPPQSCYEGGLFRLELFLPEEYP MKPPKVRFLTRIYHPNVDKVGRICLDIIKDKWSPALLINKVLLSIQILMSSPNPDDPLAN DVAEHWKEDEASALQTAREWTRKYAKP |
DNA Sequence | >LmjF04.0680 |||ubiquitin-conjugating enzyme E2, putative|Leishmania major|chr 4|||Manual ATGCTCACAA CACGTATTAT TAAGGAGACG GAGAAACTCC AGAAGGAGTG TCCGCCGGGCATCACGGCCA CACCCACCAA GGAGAACCCG CGCTACTTTA TGGTGACCAT CCAGGGGCCGCCGCAGTCGT GCTACGAGGG CGGCCTCTTC CGCCTGGAGC TGTTCCTGCC CGAGGAGTACCCGATGAAGC CGCCGAAGGT TCGCTTCCTC ACGCGTATCT ATCACCCCAA CGTAGACAAGGTGGGTCGCA TCTGTCTCGA CATCATCAAG GATAAGTGGT CGCCGGCGCT GCTCATCAACAAGGTGCTGC TATCTATCCA GATCCTCATG TCGAGCCCAA ACCCAGATGA TCCTCTGGCGAACGACGTCG CGGAGCACTG GAAGGAAGAC GAGGCCAGCG CGCTGCAGAC GGCCCGCGAGTGGACGCGCA AGTACGCCAA GCCGTGA |
Ubiquitin-conjugating enzyme E2 Q9NED4] | |
---|---|
Metabolite Information | |
Molecular Function | |
Biochemical Pathway | |
Regulatory Pathway | |
KEGG Pathways | K10580 |
Orthologs | ||||
Homologs | GI | Percent Identity | Evalue | Score |
Homo sapiens | ubiquitin-conjugating enzyme E2N [Homo sapiens] | 70 | 8e-56 | 212 |
DEG Information | ||||
DEG Protein | DEG Organism | Percent Identity | Evalue | Bit Score |
YDL064w E2 ubiquitin-conjugating enzyme | Saccharomyces cerevisiae | 31% | 1e-18 | 86.3 |
Post Translational Modification | ||||
PTM Type | PTM Sub Type | Score | Modification Site | Prosite ID |
PDOC00163 | Ubiquitin-conjugating enzymes signature and profile | 74-88; | PS00183 | |
PDOC00163 | Ubiquitin-conjugating enzymes signature and profile | 40.233 | 4-136; - | PS50127 |
Phosphorylation | Casein kinase II phosphorylation site | 43-46; 137-140; | PS00006 | |
Phosphorylation | Protein kinase C phosphorylation site | 3-5; 10-12; 137-139; 142-144; | PS00005 |
Ubiquitin-conjugating enzyme E2 [Q9NED4] | ||
---|---|---|
Model Information | ||
Template PDB ID | 2c2vK | |
Percent Identity | 70% | |
Target Region | 1-148 | |
Template Region | 3-152 |
Domain Information | ||
---|---|---|
Domains | Start | End |
Active Site Information | ||
---|---|---|
Residue | Active Site Number | Functional Part |
Co-Factor | |
---|---|
Metal | Description |
Ligands | |||||
---|---|---|---|---|---|
CAS number | Name | Mol. Weight | Mol. Formula | Smile Notation | PDB Reference |
Mutational Information | ||
---|---|---|
Residue | Feature | Description |
|
|
Modeled Protein | Template Structure |
|
+----------<<< P R O C H E C K S U M = M A R Y >>>----------+ | = | | /var/www/html/Services/SAVES_3/jobs/1466916/Q9NED4.pdb 2.0 148 = residues | | = | +| Ramachandran plot: 92.9% core 5.6% allow 1.6% gener 0.0% = disall | | = | +| All Ramachandrans: 2 labelled residues (out of 146) = | +| Chi1-chi2 plots: 1 labelled residues (out of 94) = | | = | | Main-chain params: 6 better 0 inside 0 worse = | | Side-chain params: 5 better 0 inside 0 worse = | | = | *| Residue properties: Max.deviation: 3.9 Bad contacts: = 3 | *| Bond len/angle: 9.4 Morris et al class: 1 = 1 2 | +| 2 cis-peptides = | | G-factors Dihedrals: -0.10 Covalent: -0.39 Overall: = -0.20 | | = | | M/c bond lengths: 97.5% within limits 2.5% highlighted = | *| M/c bond angles: 89.6% within limits 10.4% highlighted 1 off = graph | | Planar groups: 100.0% within limits 0.0% highlighted = | | = | = +------------------------------------------------------------------------= ----+ + May be worth investigating further. * Worth investigating further. |