| Inhibitor of cysteine peptidase [Q868G9] | |
|---|---|
| Systematic Name | LmjF.24.1770 [Leishmania major] |
| Gene Name | ICP |
| Molecular Weight | 12979 Da |
| Protein Sequence Size | 117 |
| Function | |
| Charge | 5 |
| Isoelectric Point | 9.4251 pH |
| Description | Inhibitor of cysteine peptidase. |
| Subcellular Location | N.A.[Predict] |
| E. C. Number | N.A. |
| Sequence | >tr|Q868G9|Q868G9_LEIMA Inhibitor of cysteine peptidase - Leishmania major. QPKMTAPLTMKDNNKCLSVRVGSTLEIHLEGNPTTGYTWTRVGFVGKEMLSDEHLEVTSK YTPKPVSGSMVGAGGSYTVFVKPLRKGQHAVQLVYARPFEGPKPDNERYTLHLNVE |
| DNA Sequence | >LmjF24.1770 |||inhibitor of cysteine peptidase|Leishmania major|chr 24|||Manual ATGCAACCAA AAATGACCGC CCCGCTCACT ATGAAGGACA ACAACAAGTG TTTGAGCGTGCGCGTCGGCA GCACGCTCGA GATCCACCTG GAGGGCAACC CTACCACTGG CTACACGTGGACGCGCGTCG GCTTTGTGGG CAAGGAGATG CTCAGCGATG AGCACCTGGA GGTCACCTCCAAGTACACGC CGAAACCAGT CTCGGGTTCT ATGGTGGGGG CTGGTGGCTC CTACACGGTGTTCGTGAAAC CGCTGAGAAA GGGCCAGCAC GCGGTACAGC TGGTCTACGC GCGCCCTTTCGAGGGCCCTA AGCCAGATAA CGAGAGGTAC ACGTTGCACC TCAACGTTGA GTAG |
| Inhibitor of cysteine peptidase Q868G9] | |
|---|---|
| Metabolite Information | |
| Molecular Function | endopeptidase inhibitor activity |
| Biochemical Pathway | regulation of proteolysis |
| Regulatory Pathway | |
| KEGG Pathways | |
| Orthologs | ||||
| Homologs | GI | Percent Identity | Evalue | Score |
| Homo sapiens | alpha 1 type XII collagen long isoform precursor [Homo sapiens] | 33 | 0.022 | 34 |
| DEG Information | ||||
| DEG Protein | DEG Organism | Percent Identity | Evalue | Bit Score |
| purD phosphoribosylamine--glycine ligase | Mycobacterium tuberculosis H37Rv | 31% | 1.9 | 25 |
| Post Translational Modification | ||||
| PTM Type | PTM Sub Type | Score | Modification Site | Prosite ID |
| Acylation | N-myristoylation site | 32-37; 69-74; 73-78; 75-80; | PS00008 | |
| Phosphorylation | Casein kinase II phosphorylation site | 10-13; 24-27; | PS00006 | |
| Phosphorylation | Protein kinase C phosphorylation site | 10-12; 19-21; 59-61; 63-65; | PS00005 | |
| Inhibitor of cysteine peptidase [Q868G9] | ||
|---|---|---|
| Model Information | ||
| Template PDB ID | 2c34A | |
| Percent Identity | 67% | |
| Target Region | 1-48 | |
| Template Region | 1-47 | |
| Domain Information | ||
|---|---|---|
| Domains | Start | End |
| Active Site Information | ||
|---|---|---|
| Residue | Active Site Number | Functional Part |
| Co-Factor | |
|---|---|
| Metal | Description |
| Ligands | |||||
|---|---|---|---|---|---|
| CAS number | Name | Mol. Weight | Mol. Formula | Smile Notation | PDB Reference |
| Mutational Information | ||
|---|---|---|
| Residue | Feature | Description |
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| Modeled Protein | Template Structure |
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+----------<<< P R O C H E C K S U M = M A R Y >>>----------+ | = | | /var/www/html/Services/SAVES_3/jobs/1744368/Q868G9.pdb 2.0 48 = residues | | = | *| Ramachandran plot: 78.9% core 15.8% allow 5.3% gener 0.0% = disall | | = | *| All Ramachandrans: 5 labelled residues (out of 46) = | *| Chi1-chi2 plots: 1 labelled residues (out of 25) = | | = | | Main-chain params: 6 better 0 inside 0 worse = | | Side-chain params: 5 better 0 inside 0 worse = | | = | *| Residue properties: Max.deviation: 3.8 Bad contacts: = 2 | *| Bond len/angle: 7.1 Morris et al class: 1 = 1 4 | | = | +| G-factors Dihedrals: -0.30 Covalent: -0.60 Overall: = -0.40 | | = | | M/c bond lengths: 96.6% within limits 3.4% highlighted = | | M/c bond angles: 88.2% within limits 11.8% highlighted = | | Planar groups: 100.0% within limits 0.0% highlighted = | | = | = +------------------------------------------------------------------------= ----+ + May be worth investigating further. * Worth investigating further. |