| 60S ribosomal protein L11 [Q7K6M4] | |
|---|---|
| Systematic Name | LmjF.22.0030 [Leishmania major] |
| Gene Name | P1421.04 |
| Molecular Weight | 21645 Da |
| Protein Sequence Size | 188 |
| Function | |
| Charge | 22.5 |
| Isoelectric Point | 10.6858 pH |
| Description | 60S ribosomal protein L11 (L5, L16). |
| Subcellular Location | cytosolic large ribosomal subunit (sensu Eukaryota); intracellular; ribosome[Predict] |
| E. C. Number | N.A. |
| Sequence | >tr|Q7K6M4|Q7K6M4_LEIMA 60S ribosomal protein L11 (L5, L16) - Leishmania major. VAESKAANPMREIVVKKLCINICVGESGDRLTRASKVLEQLCEQTPVLSRARLTVRTFGI RRNEKIAVHCTVRGKKAEELLEKGLKVKEFELKSYNFADTGSFGFGIDEHIDLGIKYDPS TGIYGMDFYVVLGRRGERVAHRKRKCSRVGHSHHVTKEEAMKWFEKVHDGIIFQAKKKKK MIRRRRR |
| DNA Sequence | >LmjF22.0030 |RPL11||60S ribosomal protein L11 (L5, L16)|Leishmania major|chr 22|||Manual ATGGTCGCCG AGAGCAAGGC TGCGAACCCC ATGCGGGAGA TCGTCGTGAA GAAGCTCTGCATCAACATTT GCGTTGGTGA GAGCGGTGAT CGCCTGACGC GTGCCTCGAA GGTGCTCGAGCAGCTGTGCG AGCAGACCCC GGTGCTCTCC CGCGCTCGTC TGACCGTGCG CACGTTCGGCATCCGTCGTA ACGAGAAGAT CGCCGTGCAC TGCACCGTCC GCGGCAAGAA GGCCGAGGAGCTGCTGGAGA AGGGCCTCAA GGTGAAGGAG TTCGAGCTGA AGAGCTACAA CTTCGCCGACACCGGCTCCT TCGGCTTCGG CATCGACGAG CACATTGATC TCGGCATCAA GTACGACCCCTCCACCGGTA TCTACGGCAT GGACTTCTAC GTCGTCCTCG GCCGCCGTGG TGAGCGAGTGGCGCACCGCA AGCGCAAGTG CAGCCGCGTC GGCCACTCCC ACCACGTCAC CAAGGAGGAGGCGATGAAGT GGTTCGAGAA AGTCCACGAC GGTATCATCT TCCAGGCCAA GAAGAAGAAGAAGATGATCC GCCGCCGCCG TCGCTAA |
| 60S ribosomal protein L11 Q7K6M4] | |
|---|---|
| Metabolite Information | |
| Molecular Function | structural constituent of ribosome |
| Biochemical Pathway | protein biosynthesis |
| Regulatory Pathway | |
| KEGG Pathways | K02868 |
| Orthologs | ||||
| Homologs | GI | Percent Identity | Evalue | Score |
| Homo sapiens | ribosomal protein L11 [Homo sapiens] | 62 | 2e-58 | 222 |
| DEG Information | ||||
| DEG Protein | DEG Organism | Percent Identity | Evalue | Bit Score |
| acrB cation/multidrug efflux pump | Salmonella typhimurium | 29% | 2.8 | 25.8 |
| Post Translational Modification | ||||
| PTM Type | PTM Sub Type | Score | Modification Site | Prosite ID |
| PDOC00309 | Ribosomal protein L5 signature | 39-55; | PS00358 | |
| PDOC00015 | The rule PS00015 has been deleted from the PROSITE database and replaced by the following motif: PS50079 (Bipartite nuclear localization signal profile | 62-78; | PS00015 | |
| Acylation | N-myristoylation site | 60-65; | PS00008 | |
| Amidation | Amidation site | 74-77; 133-136; | PS00009 | |
| Phosphorylation | cAMP- and cGMP-dependent protein kinase phosphorylation site | 145-148; | PS00004 | |
| Phosphorylation | Casein kinase II phosphorylation site | 157-160; | PS00006 | |
| Phosphorylation | Protein kinase C phosphorylation site | 55-57; 72-74; | PS00005 | |
| Phosphorylation | Tyrosine kinase phosphorylation site | 89-96; | PS00007 | |
| 60S ribosomal protein L11 [Q7K6M4] | ||
|---|---|---|
| Model Information | ||
| Template PDB ID | 1s1iJ | |
| Percent Identity | 62% | |
| Target Region | 9-173 | |
| Template Region | 6-165 | |
| Domain Information | ||
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| Domains | Start | End |
| Active Site Information | ||
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| Residue | Active Site Number | Functional Part |
| Co-Factor | |
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| Metal | Description |
| Ligands | |||||
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| CAS number | Name | Mol. Weight | Mol. Formula | Smile Notation | PDB Reference |
| Mutational Information | ||
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| Residue | Feature | Description |
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| Modeled Protein | Template Structure |
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+----------<<< P R O C H E C K S U M = M A R Y >>>----------+ | = | | /var/www/html/Services/SAVES_3/jobs/1123680/Q7K6M4.pdb 2.0 165 = residues | | = | *| Ramachandran plot: 62.1% core 27.6% allow 4.8% gener 5.5% = disall | | = | *| All Ramachandrans: 27 labelled residues (out of 163) = | | Chi1-chi2 plots: 0 labelled residues (out of 104) = | | = | +| Main-chain params: 5 better 0 inside 1 worse = | | Side-chain params: 5 better 0 inside 0 worse = | | = | *| Residue properties: Max.deviation: 5.4 Bad contacts: = 19 | *| Bond len/angle: 11.9 Morris et al class: 3 = 1 4 | | = | +| G-factors Dihedrals: -0.56 Covalent: -0.75 Overall: = -0.61 | | = | | M/c bond lengths: 98.0% within limits 2.0% highlighted = | *| M/c bond angles: 83.2% within limits 16.8% highlighted 2 off = graph | +| Planar groups: 98.4% within limits 1.6% highlighted = | | = | = +------------------------------------------------------------------------= ----+ + May be worth investigating further. * Worth investigating further. |