| ATP/ADP translocase [Q68H94] | |
|---|---|
| Systematic Name | LmjF.19.0200 [Leishmania major] |
| Gene Name | |
| Molecular Weight | 35077 Da |
| Protein Sequence Size | 317 |
| Function | |
| Charge | 21 |
| Isoelectric Point | 10.5 pH |
| Description | ATP/ADP translocase (ADP,ATP carrier protein 1, mitochondrial, putative) (Adp/atp translocase 1, putative). |
| Subcellular Location | membrane; mitochondrial inner membrane[Predict] |
| E. C. Number | N.A. |
| Sequence | >tr|Q68H94|Q68H94_LEIMA ATP/ADP translocase (ADP,ATP carrier protein 1, mitochondrial, putative) (Adp/atp translocase 1, putative) - Leishmania major. SANNNSAAAPKKARQDMPKLGFWEEFMISGVAAGAAKTAAAPIERVKLLVQNQGEMIKQG TLDRPYSGVMNCLTRTVKTEGLYALWRGNLSNVIRYFPTQALNFAFKDQFKRMFNYKKDR DGYMKWFMGNMASGGLAGAVSLCFVYSLDYVRTRLANDTKSAKKGGERQYSGMVDCYIKT FKTDGLVGLYRGFCVSCVGIVAYRGFYFGLYDTLQPMLPVNNFIVNFMLGWVVTIVSGLI SYPLDTVRRRMMMTSGTGKNYRNSLECFMQCVKNEGAASLFRGAGANILRGVAGALVLSG VDAIKPYYISARAAKN |
| DNA Sequence | >LmjF19.0200 |ANC1||ADP,ATP carrier protein 1, mitochondrial precursor, putative|Leishmania major|chr 19|||Manual ATGTCTGCCA ACAATAACTC TGCGGCCGCC CCGAAGAAGG CGCGCCAGGA TATGCCGAAGCTTGGCTTCT GGGAGGAGTT CATGATCAGC GGTGTGGCCG CTGGCGCTGC CAAGACGGCTGCGGCGCCGA TCGAGCGTGT GAAGCTGCTG GTGCAGAACC AGGGTGAGAT GATCAAGCAGGGCACGCTCG ACCGCCCGTA CAGCGGCGTG ATGAACTGCC TGACGCGCAC AGTGAAGACGGAGGGCTTGT ACGCGCTGTG GCGCGGCAAC CTGTCGAACG TGATCCGCTA CTTCCCGACGCAGGCGCTGA ACTTCGCGTT CAAGGACCAG TTCAAGCGTA TGTTCAACTA CAAGAAGGACCGTGACGGCT ACATGAAGTG GTTCATGGGC AACATGGCGT CCGGCGGTCT CGCCGGCGCTGTGTCGCTGT GCTTCGTGTA CTCGCTGGAC TACGTGCGTA CCCGCCTCGC GAACGACACGAAGTCTGCAA AGAAGGGTGG CGAGCGCCAG TACAGCGGCA TGGTGGACTG CTACATCAAGACGTTCAAGA CCGACGGCCT GGTAGGTCTG TACCGCGGCT TCTGCGTGTC ATGCGTGGGCATTGTTGCGT ACCGCGGCTT CTACTTCGGC TTGTACGACA CGCTGCAGCC GATGCTGCCGGTGAACAACT TCATTGTGAA CTTCATGCTG GGCTGGGTTG TGACCATCGT GTCTGGCCTGATCTCATACC CGCTGGACAC GGTGCGCCGT CGCATGATGA TGACGTCCGG CACCGGCAAGAACTACCGCA ACTCGCTTGA GTGCTTTATG CAGTGCGTGA AGAACGAGGG CGCGGCTTCGCTGTTCCGCG GTGCTGGCGC GAACATTCTG CGTGGTGTCG CTGGTGCGCT GGTGCTATCTGGCGTTGATG CTATCAAGCC GTACTACATC AGTGCTCGCG CGGCGAAGAA TTGA |
| ATP/ADP translocase Q68H94] | |
|---|---|
| Metabolite Information | |
| Molecular Function | binding; transporter activity |
| Biochemical Pathway | transport |
| Regulatory Pathway | |
| KEGG Pathways | K05863 |
| Orthologs | ||||
| Homologs | GI | Percent Identity | Evalue | Score |
| Homo sapiens | solute carrier family 25, member 5 [Homo sapiens] | 49 | 5e-76 | 281 |
| DEG Information | ||||
| DEG Protein | DEG Organism | Percent Identity | Evalue | Bit Score |
| Post Translational Modification | ||||
| PTM Type | PTM Sub Type | Score | Modification Site | Prosite ID |
| PDOC00189 | Solute carrier (Solcar) repeat profile | 25.366; 24.401; 19.810 | 25-114; 126-218; 222-308 | PS50920 |
| Acylation | N-myristoylation site | 31-36; 35-40; 69-74; 89-94; 130-135; 135-140; 136-141; 173-178; 189-194; 210-215; 257-262; 284-289; 292-297; | PS00008 | |
| Glycosylation | N-glycosylation site | 5-8; 90-93; 158-161; | PS00001 | |
| Phosphorylation | Casein kinase II phosphorylation site | 300-303; | PS00006 | |
| Phosphorylation | Protein kinase C phosphorylation site | 77-79; 162-164; 181-183; 247-249; 258-260; 311-313; | PS00005 | |
| Phosphorylation | Tyrosine kinase phosphorylation site | 164-171; | PS00007 | |
| ATP/ADP translocase [Q68H94] | ||
|---|---|---|
| Model Information | ||
| Template PDB ID | 2c3eA | |
| Percent Identity | 48% | |
| Target Region | 19-325 | |
| Template Region | 3-293 | |
| Domain Information | ||
|---|---|---|
| Domains | Start | End |
| Active Site Information | ||
|---|---|---|
| Residue | Active Site Number | Functional Part |
| Co-Factor | |
|---|---|
| Metal | Description |
| Ligands | |||||
|---|---|---|---|---|---|
| CAS number | Name | Mol. Weight | Mol. Formula | Smile Notation | PDB Reference |
| CARDIOLIPIN | 1464.04 | C81 H156 O17 P2 | CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC(COP(=O)([O-])OCC(COC(=O)CCCCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCCCC)O)OC(=O)CCCCCCCCCCCCCCCCC | 2c3e | |
| 35988-42-2 | CARBOXYATRACTYLOSIDE | 770.816 | C31 H46 O18 S2 | O=S(=O)(O)OC5C(OC(OC1CC4(C)C(C(C(=O)O)(C(=O)O)C1)CCC23C(O)/C(=C)C(C2)CCC34)C(OC(=O)CC(C)C)C5OS(=O)(=O)O)CO | 2c3e |
| Mutational Information | ||
|---|---|---|
| Residue | Feature | Description |
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| Modeled Protein | Template Structure |
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+----------<<< P R O C H E C K S U M = M A R Y >>>----------+ | = | | /var/www/html/Services/SAVES_3/jobs/3597954/Q68H94.pdb 2.0 299 = residues | | = | +| Ramachandran plot: 93.8% core 5.0% allow 1.2% gener 0.0% = disall | | = | +| All Ramachandrans: 6 labelled residues (out of 297) = | +| Chi1-chi2 plots: 4 labelled residues (out of 171) = | | = | | Main-chain params: 6 better 0 inside 0 worse = | | Side-chain params: 5 better 0 inside 0 worse = | | = | *| Residue properties: Max.deviation: 7.6 Bad contacts: = 6 | *| Bond len/angle: 5.4 Morris et al class: 1 = 1 2 | | = | | G-factors Dihedrals: 0.15 Covalent: -0.08 Overall: = 0.06 | | = | | M/c bond lengths: 99.5% within limits 0.5% highlighted = | | M/c bond angles: 95.9% within limits 4.1% highlighted = | | Planar groups: 100.0% within limits 0.0% highlighted = | | = | = +------------------------------------------------------------------------= ----+ + May be worth investigating further. * Worth investigating further. |