| Major vault protein, putative [Q4QJJ7] | |
|---|---|
| Systematic Name | LmjF.05.0060 [Leishmania major] |
| Gene Name | LMJF_05_0060 |
| Molecular Weight | 93301 Da |
| Protein Sequence Size | 833 |
| Function | |
| Charge | 4.5 |
| Isoelectric Point | 6.9 pH |
| Description | Major vault protein, putative. |
| Subcellular Location | ribonucleoprotein complex[Predict] |
| E. C. Number | N.A. |
| Sequence | >tr|Q4QJJ7|Q4QJJ7_LEIMA Major vault protein, putative - Leishmania major. SDSVIRIKRYHYIHILDNNTNVTRTISGPVVYTRKEHETCLFDPCPCVSVPPRHYCVVKN PCVRDEAGEVVLESSGQVKLRLGDAEIRFEGEPFPLYPGEELDCRDGKGVQKLQLIPPNT GLHVRCVRDFKDADRLVGAGTEWMVAGPQTYIPRVEVVVVEEVKATVIYPNTALMVQANV NFTDRGGVPRVAGEKWLVRALGAYLQSVEETVLGLIQGTMLSDLKALRLSAVRSFTDVYG KGRRAGEQWQVTLKDAPVHIIDAYEMKVADVAAVSLSAKEYVIIHHPVDDTGHNRFGETL VRRGECTFFLQPGETMPRGVEQVLVVGKEEALLLEAVCEYRDRGEKRQPGSRWMVRGPLE YIPANEVKLLEHRRMMALDKNEGIYVMNTTTGEVRAVIGKPYMLDVNEVLWEKHLPLAVE ELLESPNGSIQTSERNPGFVSHREKYRIVRFNVQHNAAVQIYDYRKKQPRIVLGPNLVML APHEEFTVLSLSGGTPKVPNSLQSLQLFLGPRFSSDTIVVETSDHARLRLRLSYNWYFDI DRVNPSQRTFSVPDFIGDCCKTIASRVRGAVASEDFDSFHRNSAKIIRTAVFGVDETGET KKNLRFTANDFVVTNIDVQSSEPTDEKTRDSLQKSVQLAIEITTKSQEAAARHGNELKDQ EAKGQLERQKLLDKIEVENARTKWLELQAKSEAVQASGQSVAEAKARAEALLIEVRSEMQ QAEMRARAYRISAEAELQKLQQRQALELEYTQRQNEIDVSKARAAAEAEAEKVKRMVDCI GRDTLVAIARAGPETQVKLLSSLGLKGYLITDGNSPVNLFGTAQGMIGEPKK |
| DNA Sequence | >LmjF05.0060 |||major vault protein, putative|Leishmania major|chr 5|||Manual ATGTCTGATT CTGTTATCCG CATCAAGCGG TACCACTACA TCCACATCTT GGACAACAACACCAACGTCA CTCGCACCAT CTCCGGCCCG GTCGTCTACA CGCGGAAGGA GCACGAGACATGCCTGTTCG ACCCGTGCCC GTGCGTGTCG GTGCCGCCGC GTCACTACTG TGTTGTCAAGAATCCATGCG TGCGAGATGA GGCGGGGGAG GTGGTGTTGG AGTCGTCGGG GCAAGTAAAGCTCCGTCTCG GCGACGCTGA GATCCGCTTT GAAGGCGAGC CTTTTCCCCT GTACCCCGGCGAGGAGCTCG ACTGCAGGGA CGGTAAAGGT GTGCAGAAGC TGCAGCTGAT CCCGCCCAACACTGGCCTCC ACGTGCGGTG CGTTCGCGAC TTCAAAGACG CGGACAGGCT TGTCGGTGCGGGTACGGAGT GGATGGTTGC TGGGCCGCAA ACGTACATCC CGCGCGTTGA GGTGGTGGTGGTGGAGGAGG TGAAGGCAAC GGTCATTTAC CCAAACACCG CCTTGATGGT GCAGGCGAACGTCAACTTCA CCGATCGAGG CGGGGTGCCT CGGGTGGCGG GGGAGAAGTG GCTGGTGCGGGCATTGGGAG CGTATCTCCA ATCTGTTGAG GAGACGGTCC TAGGCTTGAT ACAGGGTACCATGCTCAGCG ACCTCAAGGC GCTGCGCCTG AGCGCCGTGC GCAGCTTCAC CGACGTATATGGGAAAGGGC GGCGGGCTGG GGAGCAGTGG CAAGTGACAT TGAAGGACGC TCCAGTGCACATCATTGATG CCTACGAGAT GAAGGTGGCC GACGTCGCCG CCGTCTCACT CAGCGCGAAGGAGTATGTGA TCATTCACCA CCCTGTCGAC GACACCGGCC ACAACCGCTT CGGTGAGACGCTTGTGCGCC GTGGCGAGTG CACCTTTTTT CTGCAGCCAG GGGAGACGAT GCCGCGCGGTGTCGAGCAGG TGCTCGTGGT CGGAAAGGAA GAGGCGCTGC TGCTGGAGGC GGTGTGCGAGTACCGTGACC GAGGTGAGAA GCGGCAGCCG GGTAGCCGAT GGATGGTGCG CGGCCCTCTCGAGTACATCC CCGCCAACGA AGTGAAGCTG CTGGAGCACC GCCGTATGAT GGCGCTGGACAAGAACGAGG GCATTTACGT AATGAACACG ACAACGGGCG AGGTGCGTGC AGTCATCGGCAAGCCTTACA TGCTGGATGT CAACGAGGTG CTGTGGGAGA AGCACCTGCC GCTCGCCGTCGAGGAGCTCC TCGAGTCTCC GAACGGCAGC ATTCAAACGA GTGAGCGCAA CCCCGGCTTTGTCAGCCACC GCGAAAAGTA CCGTATTGTC CGATTCAACG TGCAGCACAA CGCTGCAGTGCAGATTTACG ACTACCGCAA GAAGCAGCCG CGCATTGTGC TGGGCCCAAA CCTTGTCATGCTGGCCCCAC ATGAAGAGTT CACCGTGCTC TCGCTTAGCG GCGGCACTCC GAAGGTGCCGAACTCGTTGC AATCACTCCA GCTCTTTCTC GGGCCGCGCT TCTCCAGCGA CACCATTGTCGTGGAGACGT CGGATCACGC TCGCCTACGC CTGCGGCTGT CGTACAACTG GTACTTTGACATCGACCGCG TCAACCCTAG TCAGAGGACT TTCTCGGTGC CGGACTTCAT CGGCGACTGCTGCAAGACCA TCGCCAGCCG CGTGCGCGGC GCCGTCGCCT CCGAAGACTT CGACTCCTTTCACCGCAACT CTGCCAAGAT CATCCGCACT GCTGTCTTTG GCGTCGACGA GACTGGCGAGACAAAGAAGA ATCTGCGCTT CACCGCAAAC GACTTTGTTG TGACGAACAT TGACGTTCAGTCGTCGGAGC CGACGGACGA GAAGACGCGC GACAGCTTGC AGAAGTCCGT GCAGCTCGCGATTGAAATTA CGACCAAGTC ACAAGAGGCG GCTGCACGTC ACGGCAACGA GCTGAAGGACCAGGAGGCCA AAGGGCAGCT GGAGCGGCAG AAACTGCTCG ACAAGATCGA AGTGGAGAATGCAAGGACAA AGTGGCTGGA GCTGCAGGCG AAGAGCGAGG CAGTGCAGGC GAGTGGGCAGTCCGTCGCGG AGGCAAAGGC GCGCGCAGAA GCGCTGCTCA TCGAGGTGCG CTCTGAGATGCAGCAGGCGG AGATGCGGGC GAGAGCGTAC CGTATCTCCG CGGAGGCAGA GTTGCAGAAGCTGCAGCAGC GACAAGCACT GGAGCTCGAG TACACCCAGC GGCAGAATGA GATAGACGTTTCCAAGGCAC GAGCGGCGGC TGAGGCGGAG GCAGAAAAGG TGAAGCGGAT GGTCGACTGCATTGGCCGTG ACACCTTGGT CGCCATCGCT CGCGCAGGTC CCGAGACACA GGTGAAGCTGCTGAGCAGCC TCGGCCTGAA GGGCTACCTC ATCACTGACG GGAACAGTCC CGTCAATTTATTTGGCACAG CGCAAGGAAT GATTGGCGAG CCGAAGAAGT GA |
| Major vault protein, putative Q4QJJ7] | |
|---|---|
| Metabolite Information | |
| Molecular Function | molecular function unknown |
| Biochemical Pathway | response to abiotic stimulus |
| Regulatory Pathway | |
| KEGG Pathways | |
| Orthologs | ||||
| Homologs | GI | Percent Identity | Evalue | Score |
| Homo sapiens | major vault protein [Homo sapiens] | 48 | 0 | 756 |
| DEG Information | ||||
| DEG Protein | DEG Organism | Percent Identity | Evalue | Bit Score |
| hmw2 HMW2 cytadherence accessory protein | Mycoplasma genitalium | 24% | 0.023 | 35.4 |
| Post Translational Modification | ||||
| PTM Type | PTM Sub Type | Score | Modification Site | Prosite ID |
| Acylation | N-myristoylation site | 215-220; 219-224; 429-434; 570-575; 594-599; 699-704; 822-827; | PS00008 | |
| Amidation | Amidation site | 242-245; | PS00009 | |
| Glycosylation | N-glycosylation site | 19-22; 22-25; 182-185; 389-392; 428-431; | PS00001 | |
| Phosphorylation | Casein kinase II phosphorylation site | 34-37; 208-211; 235-238; 253-256; 278-281; 391-394; 442-445; 552-555; 608-611; 615-618; 701-704; | PS00006 | |
| Phosphorylation | Protein kinase C phosphorylation site | 34-36; 184-186; 253-255; 278-280; 434-436; 442-444; 496-498; 547-549; 584-586; 601-603; 644-646; 752-754; | PS00005 | |
| Phosphorylation | Tyrosine kinase phosphorylation site | 744-751; | PS00007 | |
| Major vault protein, putative [Q4QJJ7] | ||
|---|---|---|
| Model Information | ||
| Template PDB ID | 2qzvB | |
| Percent Identity | 47% | |
| Target Region | 1-780 | |
| Template Region | 3-749 | |
| Domain Information | ||
|---|---|---|
| Domains | Start | End |
| Active Site Information | ||
|---|---|---|
| Residue | Active Site Number | Functional Part |
| Co-Factor | |
|---|---|
| Metal | Description |
| Ligands | |||||
|---|---|---|---|---|---|
| CAS number | Name | Mol. Weight | Mol. Formula | Smile Notation | PDB Reference |
| Mutational Information | ||
|---|---|---|
| Residue | Feature | Description |
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| Modeled Protein | Template Structure |
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+----------<<< P R O C H E C K S U M = M A R Y >>>----------+ | = | | /var/www/html/Services/SAVES_3/jobs/5172720/Q4QJJ7.pdb 2.0 758 = residues | | = | *| Ramachandran plot: 80.4% core 14.1% allow 2.5% gener 3.0% = disall | | = | *| All Ramachandrans: 64 labelled residues (out of 756) = | +| Chi1-chi2 plots: 9 labelled residues (out of 451) = | | = | | Main-chain params: 6 better 0 inside 0 worse = | | Side-chain params: 5 better 0 inside 0 worse = | | = | *| Residue properties: Max.deviation: 4.0 Bad contacts: = 28 | *| Bond len/angle: 8.4 Morris et al class: 1 = 1 3 | | = | | G-factors Dihedrals: -0.15 Covalent: -0.28 Overall: = -0.19 | | = | | M/c bond lengths: 98.7% within limits 1.3% highlighted = | *| M/c bond angles: 92.9% within limits 7.1% highlighted 1 off = graph | | Planar groups: 100.0% within limits 0.0% highlighted = | | = | = +------------------------------------------------------------------------= ----+ + May be worth investigating further. * Worth investigating further. |