| Histone h4 [Q4QJ78] | |
|---|---|
| Systematic Name | LmjF.06.0010 [Leishmania major] |
| Gene Name | LMJF_06_0010 |
| Molecular Weight | 11366 Da |
| Protein Sequence Size | 100 |
| Function | |
| Charge | 18.5 |
| Isoelectric Point | 11.1826 pH |
| Description | Histone h4. |
| Subcellular Location | nucleosome; nucleus[Predict] |
| E. C. Number | N.A. |
| Sequence | >tr|Q4QJ78|Q4QJ78_LEIMA Histone h4 - Leishmania major. AKGKRSADAKSSQKRQKKVLRDNIRGITRGCVRRMARRGGVKRISSEVYGEVRRVLKAYL EDIVRCSTAYTEYARKKTVTACDVVNALRQKGHILYGYA |
| DNA Sequence | >LmjF06.0010 |||histone h4|Leishmania major|chr 6|||Manual ATGGCCAAGG GCAAGCGCTC CGCTGATGCC AAGAGCAGCC AGAAGCGCCA GAAGAAGGTGCTGCGCGACA ACATCCGCGG CATCACTCGC GGCTGCGTCC GCCGCATGGC GCGCCGCGGTGGCGTGAAGC GCATCTCGAG CGAGGTGTAC GGAGAGGTGC GCCGCGTGCT GAAGGCCTACTTGGAGGACA TTGTGCGCTG CAGCACGGCC TACACCGAGT ACGCGCGCAA GAAGACCGTGACGGCGTGCG ATGTTGTGAA CGCGCTGCGC CAGAAAGGCC ACATCCTGTA CGGCTATGCGTGA |
| Histone h4 Q4QJ78] | |
|---|---|
| Metabolite Information | |
| Molecular Function | DNA binding |
| Biochemical Pathway | chromosome organization and biogenesis (sensu Eukaryota); nucleosome assembly |
| Regulatory Pathway | |
| KEGG Pathways | |
| Orthologs | ||||
| Homologs | GI | Percent Identity | Evalue | Score |
| Homo sapiens | PREDICTED: similar to germinal histone H4 gene isoform 4 [Homo sapiens] | 58 | 2e-25 | 110 |
| DEG Information | ||||
| DEG Protein | DEG Organism | Percent Identity | Evalue | Bit Score |
| YGR116w transcription elongation protein | Saccharomyces cerevisiae | 23% | 1.1 | 25 |
| Post Translational Modification | ||||
| PTM Type | PTM Sub Type | Score | Modification Site | Prosite ID |
| Acylation | N-myristoylation site | 27-32; | PS00008 | |
| Amidation | Amidation site | 3-6; | PS00009 | |
| Phosphorylation | cAMP- and cGMP-dependent protein kinase phosphorylation site | 43-46; 76-79; | PS00004 | |
| Phosphorylation | Casein kinase II phosphorylation site | 81-84; | PS00006 | |
| Phosphorylation | Protein kinase C phosphorylation site | 13-15; | PS00005 | |
| Histone h4 [Q4QJ78] | ||
|---|---|---|
| Model Information | ||
| Template PDB ID | 1id3F | |
| Percent Identity | 58% | |
| Target Region | 19-100 | |
| Template Region | 20-83 | |
| Domain Information | ||
|---|---|---|
| Domains | Start | End |
| Active Site Information | ||
|---|---|---|
| Residue | Active Site Number | Functional Part |
| Co-Factor | |
|---|---|
| Metal | Description |
| Ligands | |||||
|---|---|---|---|---|---|
| CAS number | Name | Mol. Weight | Mol. Formula | Smile Notation | PDB Reference |
| 16397-91-4 | MANGANESE (II) ION | 54.938 | Mn | [Mn+2] | 1id3 |
| Mutational Information | ||
|---|---|---|
| Residue | Feature | Description |
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| Modeled Protein | Template Structure |
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+----------<<< P R O C H E C K S U M = M A R Y >>>----------+ | = | | /var/www/html/Services/SAVES_3/jobs/1098342/Q4QJ78.pdb 2.0 82 = residues | | = | | Ramachandran plot: 95.9% core 4.1% allow 0.0% gener 0.0% = disall | | = | | All Ramachandrans: 0 labelled residues (out of 80) = | *| Chi1-chi2 plots: 2 labelled residues (out of 47) = | | = | | Main-chain params: 6 better 0 inside 0 worse = | | Side-chain params: 5 better 0 inside 0 worse = | | = | | Residue properties: Max.deviation: 2.0 Bad contacts: = 0 | +| Bond len/angle: 3.9 Morris et al class: 1 = 1 2 | | = | | G-factors Dihedrals: 0.24 Covalent: -0.06 Overall: = 0.13 | | = | | M/c bond lengths:100.0% within limits 0.0% highlighted = | | M/c bond angles: 96.9% within limits 3.1% highlighted = | | Planar groups: 100.0% within limits 0.0% highlighted = | | = | = +------------------------------------------------------------------------= ----+ + May be worth investigating further. * Worth investigating further. |