| Cell cycle associated protein MOB1, putative [Q4QIY1] | |
|---|---|
| Systematic Name | LmjF.06.0960 [Leishmania major] |
| Gene Name | MOB1 |
| Molecular Weight | 26634 Da |
| Protein Sequence Size | 223 |
| Function | |
| Charge | 4.5 |
| Isoelectric Point | 8.173 pH |
| Description | Cell cycle associated protein MOB1, putative. |
| Subcellular Location | spindle pole body[Predict] |
| E. C. Number | N.A. |
| Sequence | >tr|Q4QIY1|Q4QIY1_LEIMA Cell cycle associated protein MOB1, putative - Leishmania major. KLFGSSLFDSDKTYRPKKKHKEGTERYRLHNFARSLVKSGDLRQAVQLPPGVDSNNWLSV HTVDFYNITNVIYGSLTDYCSDMSCPVMSSGPRYEYLWRNPPEYPKATRVSAPQYLDLLM KWIERQINDERIFPSEDYNPYPADFKSYVKNIFRRMFRVYAHIYYSHFTKIAELQEEAHM NTAFKHFMYFAWEFDLIPREELTPLQELLKNLMGDYAKERLE |
| DNA Sequence | >LmjF06.0960 |MOB1||cell cycle associated protein MOB1, putative|Leishmania major|chr 6|||Manual ATGAAACTCT TCGGCAGCTC CCTCTTCGAT TCGGACAAGA CCTACCGGCC GAAGAAGAAGCACAAGGAGG GAACGGAGCG CTACCGCCTG CACAACTTTG CACGCTCGCT CGTCAAGTCTGGCGACCTGC GGCAGGCGGT GCAGCTGCCC CCTGGCGTCG ACAGCAACAA CTGGCTTTCGGTGCACACCG TTGATTTTTA CAACATCACC AATGTCATAT ACGGTTCGCT GACGGACTACTGCAGCGACA TGAGCTGCCC CGTGATGTCC TCCGGGCCGC GGTACGAGTA CCTGTGGCGCAACCCGCCCG AGTACCCCAA GGCGACGAGG GTGTCGGCGC CACAGTACCT CGACCTGCTCATGAAGTGGA TCGAGCGGCA GATCAACGAC GAGCGTATTT TTCCGTCGGA GGACTACAACCCGTACCCAG CCGACTTCAA GAGCTACGTA AAGAACATAT TCCGCCGCAT GTTCCGCGTCTACGCGCACA TATACTACTC GCACTTCACG AAGATTGCGG AGCTTCAGGA GGAGGCGCACATGAACACCG CCTTCAAGCA CTTTATGTAC TTCGCGTGGG AGTTCGACCT CATCCCACGTGAGGAGCTGA CGCCGCTGCA GGAATTGTTG AAAAACCTCA TGGGCGACTA CGCGAAGGAGCGGCTAGAGT GA |
| Cell cycle associated protein MOB1, putative Q4QIY1] | |
|---|---|
| Metabolite Information | |
| Molecular Function | molecular function unknown |
| Biochemical Pathway | regulation of progression through cell cycle |
| Regulatory Pathway | |
| KEGG Pathways | K06685 |
| Orthologs | ||||
| Homologs | GI | Percent Identity | Evalue | Score |
| Homo sapiens | MOB1, Mps One Binder kinase activator-like 1A [Homo sapiens] | 51 | 1e-63 | 239 |
| DEG Information | ||||
| DEG Protein | DEG Organism | Percent Identity | Evalue | Bit Score |
| YIL106w required for completion of mitosis and maintenance of ploidy | Saccharomyces cerevisiae | 46% | 3e-43 | 168 |
| Post Translational Modification | ||||
| PTM Type | PTM Sub Type | Score | Modification Site | Prosite ID |
| Acylation | N-myristoylation site | 52-57; | PS00008 | |
| Glycosylation | N-glycosylation site | 68-71; | PS00001 | |
| Phosphorylation | Casein kinase II phosphorylation site | 7-10; 76-79; | PS00006 | |
| Phosphorylation | Protein kinase C phosphorylation site | 11-13; 14-16; 25-27; | PS00005 | |
| Cell cycle associated protein MOB1, putative [Q4QIY1] | ||
|---|---|---|
| Model Information | ||
| Template PDB ID | 1pi1A | |
| Percent Identity | 54% | |
| Target Region | 39-223 | |
| Template Region | 16-185 | |
| Domain Information | ||
|---|---|---|
| Domains | Start | End |
| Active Site Information | ||
|---|---|---|
| Residue | Active Site Number | Functional Part |
| Co-Factor | |
|---|---|
| Metal | Description |
| Ligands | |||||
|---|---|---|---|---|---|
| CAS number | Name | Mol. Weight | Mol. Formula | Smile Notation | PDB Reference |
| 23713-49-7 | ZINC ION | 65.409 | Zn | [Zn+2] | 1pi1 |
| Mutational Information | ||
|---|---|---|
| Residue | Feature | Description |
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| Modeled Protein | Template Structure |
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+----------<<< P R O C H E C K S U M = M A R Y >>>----------+ | = | | /var/www/html/Services/SAVES_3/jobs/896797/Q4QIY1.pdb 2.0 185 = residues | | = | +| Ramachandran plot: 95.8% core 3.6% allow 0.6% gener 0.0% = disall | | = | +| All Ramachandrans: 2 labelled residues (out of 183) = | | Chi1-chi2 plots: 0 labelled residues (out of 127) = | | = | | Main-chain params: 6 better 0 inside 0 worse = | | Side-chain params: 5 better 0 inside 0 worse = | | = | *| Residue properties: Max.deviation: 4.1 Bad contacts: = 5 | *| Bond len/angle: 7.1 Morris et al class: 1 = 1 2 | | = | | G-factors Dihedrals: 0.16 Covalent: -0.14 Overall: = 0.05 | | = | | M/c bond lengths: 98.5% within limits 1.5% highlighted = | *| M/c bond angles: 94.5% within limits 5.5% highlighted 1 off = graph | | Planar groups: 100.0% within limits 0.0% highlighted = | | = | = +------------------------------------------------------------------------= ----+ + May be worth investigating further. * Worth investigating further. |