| Mitochondrial associated ribonuclease, putative [Q4QID7] | |
|---|---|
| Systematic Name | LmjF.08.0320 [Leishmania major] |
| Gene Name | LMJF_08_0320 |
| Molecular Weight | 24847 Da |
| Protein Sequence Size | 225 |
| Function | |
| Charge | 2.5 |
| Isoelectric Point | 7.1 pH |
| Description | Mitochondrial associated ribonuclease, putative. |
| Subcellular Location | N.A.[Predict] |
| E. C. Number | N.A. |
| Sequence | >tr|Q4QID7|Q4QID7_LEIMA Mitochondrial associated ribonuclease, putative - Leishmania major. AAMASRALISSPSHLLQKFDSCRTIFMCCDIQEKLRNRIPNFQAAVDVSNSMATIHNTLT PKHSTFVVTEQYPKGVGHVAKDITLPEGTPVIEKLQPSMLVPEMMPYIDGDAARGILPVQ QAVLWGHETHVCVLQTADELLSRNIRVAVLVDGCASQQQLDHDVAIQEMAGWENLTLTTT ISVLLQLSRGDRWIRGALMKVVKPKWADPSRFPSLPADGERPKA |
| DNA Sequence | >LmjF08.0320 |||mitochondrial associated ribonuclease, putative|Leishmania major|chr 8|||Manual ATGGCCGCCA TGGCGTCGCG CGCCCTCATC TCCTCGCCGT CACACCTGCT GCAGAAGTTTGACAGCTGCC GCACCATCTT CATGTGCTGC GATATCCAGG AAAAACTGCG CAACCGCATCCCCAACTTCC AGGCGGCCGT TGACGTGTCA AACTCGATGG CGACCATCCA CAACACGCTGACGCCCAAGC ACTCCACCTT TGTGGTGACG GAGCAGTACC CGAAAGGGGT GGGGCATGTTGCGAAGGACA TCACGTTGCC TGAGGGTACC CCGGTGATCG AGAAGCTGCA GCCGTCGATGCTAGTGCCGG AAATGATGCC CTACATCGAC GGTGACGCGG CGCGTGGCAT CTTGCCGGTGCAGCAAGCGG TGCTGTGGGG TCACGAGACA CACGTGTGCG TGCTTCAGAC GGCCGATGAGCTGCTGTCCC GCAACATCCG CGTGGCGGTG CTTGTGGACG GCTGCGCCTC GCAGCAGCAGCTCGATCACG ACGTAGCGAT CCAGGAGATG GCGGGATGGG AGAACCTCAC GCTGACAACCACCATCTCCG TTCTTTTGCA GCTGTCGCGT GGCGATCGCT GGATAAGGGG AGCCCTCATGAAAGTAGTGA AGCCAAAGTG GGCAGACCCC TCTCGCTTCC CGAGCCTCCC CGCGGACGGTGAGAGGCCGA AGGCGTGA |
| Mitochondrial associated ribonuclease, putative Q4QID7] | |
|---|---|
| Metabolite Information | |
| Molecular Function | catalytic activity |
| Biochemical Pathway | metabolism |
| Regulatory Pathway | |
| KEGG Pathways | |
| Orthologs | ||||
| Homologs | GI | Percent Identity | Evalue | Score |
| Homo sapiens | isochorismatase domain containing 1 [Homo sapiens] | 36 | 6e-17 | 85 |
| DEG Information | ||||
| DEG Protein | DEG Organism | Percent Identity | Evalue | Bit Score |
| opcA PUTATIVE OXPP CYCLE PROTEIN OPCA | Mycobacterium tuberculosis H37Rv | 43% | 0.33 | 29.3 |
| Post Translational Modification | ||||
| PTM Type | PTM Sub Type | Score | Modification Site | Prosite ID |
| PDOC00016 | Cell attachment sequence | 190-192; | PS00016 | |
| Glycosylation | N-glycosylation site | 175-178; | PS00001 | |
| Phosphorylation | Casein kinase II phosphorylation site | 85-88; 137-140; 189-192; | PS00006 | |
| Phosphorylation | Protein kinase C phosphorylation site | 22-24; 61-63; | PS00005 | |
| Sulfation | Tyrosine sulfation site | 101-115; | PS00003 | |
| Mitochondrial associated ribonuclease, putative [Q4QID7] | ||
|---|---|---|
| Model Information | ||
| Template PDB ID | 1yzvA | |
| Percent Identity | 47% | |
| Target Region | 14-227 | |
| Template Region | 2-195 | |
| Domain Information | ||
|---|---|---|
| Domains | Start | End |
| Active Site Information | ||
|---|---|---|
| Residue | Active Site Number | Functional Part |
| ASP | 18 | Sidechain |
| Co-Factor | |
|---|---|
| Metal | Description |
| Ligands | |||||
|---|---|---|---|---|---|
| CAS number | Name | Mol. Weight | Mol. Formula | Smile Notation | PDB Reference |
| 14808-79-8 | SULFATE ION | 96.063 | O4 S | [O-]S([O-])(=O)=O | 1yzv |
| Mutational Information | ||
|---|---|---|
| Residue | Feature | Description |
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| Modeled Protein | Template Structure |
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+----------<<< P R O C H E C K S U M = M A R Y >>>----------+ | = | | /var/www/html/Services/SAVES_3/jobs/4497600/Q4QID7.pdb 2.0 212 = residues | | = | *| Ramachandran plot: 89.2% core 9.7% allow 0.5% gener 0.5% = disall | | = | +| All Ramachandrans: 6 labelled residues (out of 210) = | +| Chi1-chi2 plots: 1 labelled residues (out of 121) = | | = | | Main-chain params: 6 better 0 inside 0 worse = | | Side-chain params: 5 better 0 inside 0 worse = | | = | *| Residue properties: Max.deviation: 4.0 Bad contacts: = 5 | *| Bond len/angle: 5.6 Morris et al class: 1 = 1 2 | +| 1 cis-peptides = | | G-factors Dihedrals: 0.07 Covalent: -0.16 Overall: = -0.01 | | = | | M/c bond lengths: 98.8% within limits 1.2% highlighted = | | M/c bond angles: 94.0% within limits 6.0% highlighted = | | Planar groups: 100.0% within limits 0.0% highlighted = | | = | = +------------------------------------------------------------------------= ----+ + May be worth investigating further. * Worth investigating further. |