| EF hand-like protein [Q4QG09] | |
|---|---|
| Systematic Name | LmjF.13.1450 [Leishmania major] |
| Gene Name | LMJF_13_1450 |
| Molecular Weight | 23808 Da |
| Protein Sequence Size | 216 |
| Function | |
| Charge | -7.5 |
| Isoelectric Point | 4.5383 pH |
| Description | EF hand-like protein. |
| Subcellular Location | N.A.[Predict] |
| E. C. Number | N.A. |
| Sequence | >tr|Q4QG09|Q4QG09_LEIMA EF hand-like protein - Leishmania major. GDVYPGYGCPQAPQGYRANPMYDGQQPASYPATAGSLGGGAYAPPQYPAPPELVSGFQAA DSDHNGRIDVAELNAALSSAGFRFSLGTTEKLLARYDLDRSGSITMEEFADLHEFITAMQ QGFRQCDTSGDGRLDRREALEAFRLSGFVLGEQTFQAVMRKFDRQHRGSLGFDEYIELSI FVAQVRDAFAYYNRDRSCQVLFNFDTFLGTAAAIW |
| DNA Sequence | >LmjF13.1450 |||EF hand-like protein|Leishmania major|chr 13|||Manual ATGGGGGATG TCTACCCAGG CTACGGGTGC CCCCAAGCCC CTCAGGGCTA CAGGGCGAATCCGATGTACG ATGGACAGCA ACCCGCCAGT TACCCCGCCA CCGCCGGCTC CCTTGGCGGTGGCGCGTACG CGCCGCCGCA GTATCCAGCG CCACCAGAGT TAGTCAGTGG GTTCCAGGCGGCGGATAGCG ATCATAATGG TCGCATCGAT GTGGCCGAGC TAAACGCTGC CCTCTCCAGCGCCGGCTTCC GGTTTAGCCT TGGCACGACC GAGAAGTTGC TAGCCCGCTA CGACCTCGACCGCAGTGGCA GCATCACCAT GGAGGAGTTT GCCGACCTAC ACGAGTTTAT TACCGCAATGCAGCAAGGCT TCCGCCAGTG CGACACCAGT GGTGACGGAC GTCTCGACAG GAGAGAGGCACTCGAGGCCT TCCGGCTCAG TGGCTTCGTC CTCGGCGAGC AGACCTTCCA GGCTGTCATGCGCAAGTTTG ACCGCCAGCA CCGCGGCTCG CTCGGCTTCG ACGAATACAT CGAGCTCTCTATCTTTGTGG CGCAAGTCCG CGACGCGTTC GCCTACTATA ATCGAGACCG CAGCTGTCAGGTGCTCTTTA ACTTCGACAC CTTCCTTGGC ACGGCCGCAG CGATCTGGTA A |
| EF hand-like protein Q4QG09] | |
|---|---|
| Metabolite Information | |
| Molecular Function | calcium ion binding |
| Biochemical Pathway | |
| Regulatory Pathway | |
| KEGG Pathways | |
| Orthologs | ||||
| Homologs | GI | Percent Identity | Evalue | Score |
| Homo sapiens | programmed cell death 6 [Homo sapiens] | 29 | 5e-18 | 88 |
| DEG Information | ||||
| DEG Protein | DEG Organism | Percent Identity | Evalue | Bit Score |
| YBR109c calmodulin | Saccharomyces cerevisiae | 23% | 0.002 | 36.6 |
| Post Translational Modification | ||||
| PTM Type | PTM Sub Type | Score | Modification Site | Prosite ID |
| PDOC00018 | EF-hand calcium-binding domain signature and profile | 62-74; 98-110; | PS00018 | |
| PDOC00018 | EF-hand calcium-binding domain signature and profile | 10.608; 9.492; 7.763; 7.093 | 49-84; 85-120; 124-150; 151-186 | PS50222 |
| Acylation | N-myristoylation site | 25-30; 36-41; 210-215; | PS00008 | |
| Phosphorylation | Casein kinase II phosphorylation site | 106-109; 129-132; | PS00006 | |
| Phosphorylation | Protein kinase C phosphorylation site | 90-92; | PS00005 | |
| EF hand-like protein [Q4QG09] | ||
|---|---|---|
| Model Information | ||
| Template PDB ID | 1y1xB | |
| Percent Identity | 61% | |
| Target Region | 38-216 | |
| Template Region | 11-174 | |
| Domain Information | ||
|---|---|---|
| Domains | Start | End |
| Active Site Information | ||
|---|---|---|
| Residue | Active Site Number | Functional Part |
| Co-Factor | |
|---|---|
| Metal | Description |
| Ligands | |||||
|---|---|---|---|---|---|
| CAS number | Name | Mol. Weight | Mol. Formula | Smile Notation | PDB Reference |
| 17787-72-3 | CALCIUM ION | 40.078 | Ca | [Ca+2] | 1y1x |
| 14808-79-8 | SULFATE ION | 96.063 | O4 S   | [O-]S([O-])(=O)=O | 1y1x |
| Mutational Information | ||
|---|---|---|
| Residue | Feature | Description |
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| Modeled Protein | Template Structure |
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+----------<<< P R O C H E C K S U M = M A R Y >>>----------+ | = | | /var/www/html/Services/SAVES_3/jobs/2421045/Q4QG09.pdb 2.0 179 = residues | | = | +| Ramachandran plot: 92.9% core 5.8% allow 1.3% gener 0.0% = disall | | = | +| All Ramachandrans: 3 labelled residues (out of 177) = | +| Chi1-chi2 plots: 1 labelled residues (out of 108) = | | = | | Main-chain params: 6 better 0 inside 0 worse = | | Side-chain params: 5 better 0 inside 0 worse = | | = | *| Residue properties: Max.deviation: 17.3 Bad contacts: = 5 | *| Bond len/angle: 6.3 Morris et al class: 1 = 1 1 | | = | | G-factors Dihedrals: 0.22 Covalent: -0.05 Overall: = 0.11 | | = | | M/c bond lengths: 99.3% within limits 0.7% highlighted = | | M/c bond angles: 95.1% within limits 4.9% highlighted = | | Planar groups: 100.0% within limits 0.0% highlighted = | | = | = +------------------------------------------------------------------------= ----+ + May be worth investigating further. * Worth investigating further. |