| Histone h3, putative [Q4QEV9] | |
|---|---|
| Systematic Name | LmjF.16.0600 [Leishmania major] |
| Gene Name | LMJF_16_0600 |
| Molecular Weight | 14664 Da |
| Protein Sequence Size | 130 |
| Function | |
| Charge | 19.5 |
| Isoelectric Point | 11.7457 pH |
| Description | Histone h3, putative. |
| Subcellular Location | nucleosome; nucleus[Predict] |
| E. C. Number | N.A. |
| Sequence | >tr|Q4QEV9|Q4QEV9_LEIMA Histone h3, putative - Leishmania major. SRTKETARAKRTITSKKSKKAPSAVSGVKMSHRRWRPGTCAIREIRKFQKSTSLLIQCAP FQRLVREVSSAQKEGLRFQSSAIMALQEATEAYVVSLMADTNLACIHAKRVTIQPKDIQL ALRLRGERH |
| DNA Sequence | >LmjF16.0600 |||histone h3, putative|Leishmania major|chr 16|||Manual ATGTCCCGCA CCAAGGAGAC CGCCCGCGCG AAGCGCACCA TCACGTCGAA GAAGAGCAAGAAGGCGCCGA GCGCGGTGTC CGGCGTGAAG ATGTCGCATC GCCGCTGGCG CCCGGGCACGTGCGCGATCC GCGAGATCCG CAAGTTCCAG AAGAGCACGA GCCTGCTGAT CCAGTGCGCGCCGTTCCAGC GCCTGGTGCG CGAGGTGTCG AGCGCGCAGA AGGAGGGCCT GCGCTTCCAGAGCAGCGCTA TCATGGCGCT GCAGGAGGCG ACGGAGGCGT ACGTTGTGTC GCTGATGGCGGACACGAACC TCGCCTGCAT CCACGCGAAG CGCGTGACGA TCCAGCCGAA GGACATCCAGCTGGCGCTGC GCCTGCGCGG TGAGCGGCAC TAG |
| Histone h3, putative Q4QEV9] | |
|---|---|
| Metabolite Information | |
| Molecular Function | DNA binding |
| Biochemical Pathway | chromosome organization and biogenesis (sensu Eukaryota); nucleosome assembly |
| Regulatory Pathway | |
| KEGG Pathways | |
| Orthologs | ||||
| Homologs | GI | Percent Identity | Evalue | Score |
| Homo sapiens | PREDICTED: similar to CG31613-PA [Homo sapiens] | 57 | 6e-34 | 139 |
| DEG Information | ||||
| DEG Protein | DEG Organism | Percent Identity | Evalue | Bit Score |
| YKL049c strong similarity to histone H3 | Saccharomyces cerevisiae | 54% | 7e-24 | 103 |
| Post Translational Modification | ||||
| PTM Type | PTM Sub Type | Score | Modification Site | Prosite ID |
| PDOC00287 | Histone H3 signatures | 61-69; | PS00959 | |
| Acylation | N-myristoylation site | 28-33; | PS00008 | |
| Phosphorylation | cAMP- and cGMP-dependent protein kinase phosphorylation site | 110-113; | PS00004 | |
| Phosphorylation | Protein kinase C phosphorylation site | 7-9; 15-17; 16-18; 19-21; 32-34; | PS00005 | |
| Histone h3, putative [Q4QEV9] | ||
|---|---|---|
| Model Information | ||
| Template PDB ID | 1f66E | |
| Percent Identity | 57% | |
| Target Region | 28-130 | |
| Template Region | 1-103 | |
| Domain Information | ||
|---|---|---|
| Domains | Start | End |
| Active Site Information | ||
|---|---|---|
| Residue | Active Site Number | Functional Part |
| Co-Factor | |
|---|---|
| Metal | Description |
| Ligands | |||||
|---|---|---|---|---|---|
| CAS number | Name | Mol. Weight | Mol. Formula | Smile Notation | PDB Reference |
| 16397-91-4 | MANGANESE (II) ION | 54.938 | Mn | [Mn+2] | 1f66 |
| Mutational Information | ||
|---|---|---|
| Residue | Feature | Description |
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| Modeled Protein | Template Structure |
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+----------<<< P R O C H E C K S U M = M A R Y >>>----------+ | = | | /var/www/html/Services/SAVES_3/jobs/2910495/Q4QEV9.pdb 2.0 103 = residues | | = | | Ramachandran plot: 97.9% core 2.1% allow 0.0% gener 0.0% = disall | | = | | All Ramachandrans: 0 labelled residues (out of 101) = | +| Chi1-chi2 plots: 1 labelled residues (out of 63) = | | = | | Main-chain params: 6 better 0 inside 0 worse = | | Side-chain params: 5 better 0 inside 0 worse = | | = | | Residue properties: Max.deviation: 2.4 Bad contacts: = 0 | +| Bond len/angle: 3.7 Morris et al class: 1 = 1 1 | | = | | G-factors Dihedrals: 0.28 Covalent: -0.06 Overall: = 0.15 | | = | | M/c bond lengths: 99.4% within limits 0.6% highlighted = | | M/c bond angles: 95.9% within limits 4.1% highlighted = | | Planar groups: 100.0% within limits 0.0% highlighted = | | = | = +------------------------------------------------------------------------= ----+ + May be worth investigating further. * Worth investigating further. |