| Transaldolase, putative [Q4QEU3] | |
|---|---|
| Systematic Name | LmjF.16.0760 [Leishmania major] |
| Gene Name | LMJF_16_0760 |
| Molecular Weight | 36963 Da |
| Protein Sequence Size | 330 |
| Function | |
| Charge | -6 |
| Isoelectric Point | 5.295 pH |
| Description | Transaldolase, putative (EC 2.2.1.2). |
| Subcellular Location | cytoplasm[Predict] |
| E. C. Number | 2.2.1.2 |
| Sequence | >tr|Q4QEU3|Q4QEU3_LEIMA Transaldolase, putative (EC 2.2.1.2) - Leishmania major. PNRLEQLREMTTVVADTANFSLMEKFQPEDATTNPSLVLAGSQMTEYAHLLTEAIDYAKA NIIKHTDHYTSDDSNENLLALALDKLTVSFGIQILKVVPGRVSTEVDAKLSFDEQKMIDK ARLLIQMYEEAGISRDRIYIKLASTWEGIQAARTLEKEGICCNLTLLFSFAQAVACAQAN VSLISPFVGRILDWYRKAEPAKADCFVGAADPGVVSVTKIYNYYKKHGYKTIVMGASFRN VEEILELAGCDKLTISPSLLEELAASEGNVTRKLHPDKVTDVEKLPELSREDFLFMHNED PMAVEKLSEGIRNFHKDTVKLRNAIHERL |
| DNA Sequence | >LmjF16.0760 |||transaldolase, putative|Leishmania major|chr 16|||Manual ATGCCAAACC GACTCGAGCA ACTCCGCGAG ATGACGACTG TCGTCGCCGA TACGGCGAACTTCAGCCTCA TGGAGAAGTT CCAGCCGGAG GATGCGACGA CGAACCCGTC ACTCGTGCTGGCCGGCTCAC AGATGACTGA ATACGCGCAC CTCTTGACCG AGGCTATCGA TTACGCCAAGGCAAACATCA TCAAGCACAC AGATCACTAC ACGAGCGATG ACAGCAACGA GAACCTGCTCGCCCTCGCGC TCGATAAGCT GACGGTCAGC TTCGGCATCC AGATATTGAA GGTCGTGCCGGGCCGCGTGA GCACCGAGGT GGACGCGAAG CTGTCCTTCG ACGAGCAAAA GATGATTGACAAGGCGCGCC TTCTTATTCA GATGTATGAG GAGGCTGGCA TCAGCCGCGA CCGCATCTACATCAAGCTCG CCTCCACCTG GGAGGGCATC CAGGCCGCTC GTACGCTGGA GAAGGAGGGCATCTGCTGCA ACCTGACGCT GCTCTTCTCG TTCGCCCAGG CGGTCGCGTG CGCGCAGGCGAACGTCTCCC TCATCTCGCC TTTCGTCGGC CGCATCCTTG ATTGGTACAG GAAGGCGGAGCCGGCCAAGG CGGACTGCTT CGTCGGCGCG GCCGACCCCG GTGTTGTCTC CGTCACTAAGATCTACAACT ACTACAAGAA GCACGGTTAC AAGACCATCG TTATGGGCGC CTCCTTCCGCAACGTTGAGG AGATCTTGGA GCTGGCCGGC TGCGACAAGC TCACCATCTC CCCCTCGCTACTGGAGGAGC TCGCAGCCAG TGAAGGCAAC GTCACCCGCA AGCTCCACCC AGACAAGGTGACGGATGTGG AAAAACTGCC AGAGCTGTCG AGAGAAGACT TCCTCTTCAT GCACAATGAGGACCCGATGG CCGTCGAGAA GCTCTCCGAG GGTATCCGCA ACTTCCACAA GGACACAGTGAAACTGAGGA ACGCCATCCA TGAGAGGCTG TAA |
| Transaldolase, putative Q4QEU3] | |
|---|---|
| Metabolite Information | |
| Molecular Function | transaldolase activity |
| Biochemical Pathway | carbohydrate metabolism; pentose-phosphate shunt |
| Regulatory Pathway | |
| KEGG Pathways | K00616 |
| Orthologs | ||||
| Homologs | GI | Percent Identity | Evalue | Score |
| Homo sapiens | transaldolase 1 [Homo sapiens] | 55 | 5e-93 | 338 |
| DEG Information | ||||
| DEG Protein | DEG Organism | Percent Identity | Evalue | Bit Score |
| tal transaldolase | Mycobacterium tuberculosis H37Rv | 37% | 0.000003 | 46.6 |
| Post Translational Modification | ||||
| PTM Type | PTM Sub Type | Score | Modification Site | Prosite ID |
| PDOC00741 | Transaldolase signatures | 139-156; | PS00958 | |
| PDOC00741 | Transaldolase signatures | 31-39; | PS01054 | |
| Acylation | N-myristoylation site | 42-47; 149-154; 160-165; | PS00008 | |
| Glycosylation | N-glycosylation site | 20-23; 164-167; 181-184; 270-273; | PS00001 | |
| Phosphorylation | Casein kinase II phosphorylation site | 22-25; 71-74; 105-108; 112-115; 145-148; 259-262; 281-284; 290-293; | PS00006 | |
| Phosphorylation | Protein kinase C phosphorylation site | 238-240; 272-274; 319-321; | PS00005 | |
| Transaldolase, putative [Q4QEU3] | ||
|---|---|---|
| Model Information | ||
| Template PDB ID | 1ucwB | |
| Percent Identity | 57% | |
| Target Region | 1-330 | |
| Template Region | 2-315 | |
| Domain Information | ||
|---|---|---|
| Domains | Start | End |
| Active Site Information | ||
|---|---|---|
| Residue | Active Site Number | Functional Part |
| ASP | 17 | Unknown |
| GLU | 106 | Unknown |
| Co-Factor | |
|---|---|
| Metal | Description |
| Ligands | |||||
|---|---|---|---|---|---|
| CAS number | Name | Mol. Weight | Mol. Formula | Smile Notation | PDB Reference |
| Mutational Information | ||
|---|---|---|
| Residue | Feature | Description |
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| Modeled Protein | Template Structure |
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+----------<<< P R O C H E C K S U M = M A R Y >>>----------+ | = | | /var/www/html/Services/SAVES_3/jobs/394383/Q4QEU3.pdb 2.0 330 = residues | | = | *| Ramachandran plot: 96.0% core 3.3% allow 0.3% gener 0.3% = disall | | = | +| All Ramachandrans: 5 labelled residues (out of 328) = | +| Chi1-chi2 plots: 1 labelled residues (out of 206) = | | = | | Main-chain params: 6 better 0 inside 0 worse = | | Side-chain params: 5 better 0 inside 0 worse = | | = | *| Residue properties: Max.deviation: 4.5 Bad contacts: = 5 | *| Bond len/angle: 17.1 Morris et al class: 1 = 1 2 | | = | | G-factors Dihedrals: 0.21 Covalent: -0.21 Overall: = 0.05 | | = | *| M/c bond lengths: 99.0% within limits 1.0% highlighted 3 off = graph | *| M/c bond angles: 95.5% within limits 4.5% highlighted 4 off = graph | | Planar groups: 100.0% within limits 0.0% highlighted = | | = | = +------------------------------------------------------------------------= ----+ + May be worth investigating further. * Worth investigating further. |