| ADP-ribosylation factor-like, putative [Q4QEM9] | |
|---|---|
| Systematic Name | LmjF.16.1380 [Leishmania major] |
| Gene Name | LMJF_16_1380 |
| Molecular Weight | 20439 Da |
| Protein Sequence Size | 182 |
| Function | |
| Charge | 2.5 |
| Isoelectric Point | 7.9 pH |
| Description | ADP-ribosylation factor-like, putative (Small gtpase, putative). |
| Subcellular Location | N.A.[Predict] |
| E. C. Number | N.A. |
| Sequence | >tr|Q4QEM9|Q4QEM9_LEIMA ADP-ribosylation factor-like, putative (Small gtpase, putative) - Leishmania major. GQAKTKLNIIICGLDNSGKTTIINFMKPENQRSENIAATVGYNVDSFKKGNVYITAFDMS GAQKFRGLWESYYSNIDGVVFVIDSSDALRLCVVKDELEQMLNHADLKACTVPFVFFANK MDLAGAKTPMELTQILQLNSLMGDHPMNIFTSNALRGEGIHEGMDWLRSMMLRRLEQSKK K |
| DNA Sequence | >LmjF16.1380 |||ADP-ribosylation factor-like, putative|Leishmania major|chr 16|||Manual ATGGGGCAAG CGAAGACGAA GCTAAACATC ATCATATGCG GGCTGGACAA CAGCGGTAAAACCACCATCA TCAACTTTAT GAAGCCGGAG AACCAGCGCT CCGAGAACAT CGCGGCCACCGTGGGGTACA ACGTGGATAG CTTCAAGAAG GGAAATGTGT ATATTACGGC GTTCGACATGAGCGGCGCGC AGAAGTTCCG CGGACTGTGG GAGAGCTACT ACAGCAACAT CGACGGCGTCGTGTTCGTGA TCGACAGCAG CGATGCCCTC CGCCTGTGCG TCGTGAAGGA CGAGCTGGAGCAGATGCTGA ACCACGCGGA CCTCAAGGCG TGCACAGTGC CGTTTGTTTT CTTTGCCAACAAGATGGACC TCGCAGGAGC CAAGACGCCG ATGGAGCTGA CGCAGATCCT GCAGCTGAATAGCCTCATGG GTGATCATCC CATGAACATC TTCACCTCCA ACGCACTACG AGGCGAGGGCATTCACGAGG GGATGGACTG GCTGCGGTCA ATGATGCTGC GCCGCCTGGA GCAGTCCAAGAAGAAGTGA |
| ADP-ribosylation factor-like, putative Q4QEM9] | |
|---|---|
| Metabolite Information | |
| Molecular Function | |
| Biochemical Pathway | |
| Regulatory Pathway | |
| KEGG Pathways | K07951 |
| Orthologs | ||||
| Homologs | GI | Percent Identity | Evalue | Score |
| Homo sapiens | ADP-ribosylation factor-like 6 [Homo sapiens] | 47 | 4e-45 | 177 |
| DEG Information | ||||
| DEG Protein | DEG Organism | Percent Identity | Evalue | Bit Score |
| YPL218w GTP-binding protein of the ARF family | Saccharomyces cerevisiae | 32% | 5e-21 | 94.7 |
| Post Translational Modification | ||||
| PTM Type | PTM Sub Type | Score | Modification Site | Prosite ID |
| PDOC00017 | ATP/GTP-binding site motif A (P-loop) | 14-21; | PS00017 | |
| Acylation | N-myristoylation site | 2-7; 14-19; 68-73; 160-165; | PS00008 | |
| Phosphorylation | Casein kinase II phosphorylation site | 56-59; 75-78; 129-132; | PS00006 | |
| Phosphorylation | Protein kinase C phosphorylation site | 18-20; 47-49; 179-181; | PS00005 | |
| Phosphorylation | Tyrosine kinase phosphorylation site | 67-74; | PS00007 | |
| ADP-ribosylation factor-like, putative [Q4QEM9] | ||
|---|---|---|
| Model Information | ||
| Template PDB ID | 2h57C | |
| Percent Identity | 47% | |
| Target Region | 7-173 | |
| Template Region | 17-166 | |
| Domain Information | ||
|---|---|---|
| Domains | Start | End |
| Active Site Information | ||
|---|---|---|
| Residue | Active Site Number | Functional Part |
| ALA | 57 | Sidechain (GLN 73 In Template) |
| Co-Factor | |
|---|---|
| Metal | Description |
| Ligands | |||||
|---|---|---|---|---|---|
| CAS number | Name | Mol. Weight | Mol. Formula | Smile Notation | PDB Reference |
| 86-01-1 | GUANOSINE-5'-TRIPHOSPHATE | 523.18 | C10 H16 N5 O14 P3 | O=P(O)(O)OP(=O)(O)OP(=O)(O)OCC3OC(n2cnc1c2N=C(N)NC1=O)C(O)C3O | 2h57 |
| 7791-18-6 | MAGNESIUM ION | 24.305 | Mg | [Mg+2] | 2h57 |
| Mutational Information | ||
|---|---|---|
| Residue | Feature | Description |
|
|
|
| Modeled Protein | Template Structure |
|
|
+----------<<< P R O C H E C K S U M = M A R Y >>>----------+ | = | | /var/www/html/Services/SAVES_3/jobs/799214/Q4QEM9.pdb 2.0 167 = residues | | = | | Ramachandran plot: 94.0% core 6.0% allow 0.0% gener 0.0% = disall | | = | +| All Ramachandrans: 2 labelled residues (out of 165) = | | Chi1-chi2 plots: 0 labelled residues (out of 108) = | | = | | Main-chain params: 6 better 0 inside 0 worse = | | Side-chain params: 5 better 0 inside 0 worse = | | = | *| Residue properties: Max.deviation: 2.8 Bad contacts: = 0 | *| Bond len/angle: 6.4 Morris et al class: 1 = 1 2 | | = | | G-factors Dihedrals: 0.08 Covalent: -0.08 Overall: = 0.02 | | = | | M/c bond lengths:100.0% within limits 0.0% highlighted = | | M/c bond angles: 94.8% within limits 5.2% highlighted = | | Planar groups: 100.0% within limits 0.0% highlighted = | | = | = +------------------------------------------------------------------------= ----+ + May be worth investigating further. * Worth investigating further. |