| 60S ribosomal protein L10a, putative [Q4QDX9] | |
|---|---|
| Systematic Name | LmjF.18.0620 [Leishmania major] |
| Gene Name | RPL10a |
| Molecular Weight | 24530 Da |
| Protein Sequence Size | 214 |
| Function | |
| Charge | 19 |
| Isoelectric Point | 10.3 pH |
| Description | 60S ribosomal protein L10a, putative. |
| Subcellular Location | cytosolic large ribosomal subunit (sensu Eukaryota); intracellular[Predict] |
| E. C. Number | N.A. |
| Sequence | >tr|Q4QDX9|Q4QDX9_LEIMA 60S ribosomal protein L10a, putative - Leishmania major. SKIAPQTLMEAIQAVLKVDKERKFKESVDLQVNLKNYDPQKDKRFSGSLKLPNVCRPRMT VCLLCDLVHEDIAKKEGVPTMNQEELKKLNKNKKLVKKMCNQYDAFLCSESIIKTVPRLV GPHMHRMGKFPTVCSPSESLADKIVELRSTVKFQLKKVLCLGTCVGHMEMSEEQLRQNVT MAINFLVSLLKKNWQNLKSAYIKSTMGKPQRIY |
| DNA Sequence | >LmjF18.0620 |||60S ribosomal protein L10a, putative|Leishmania major|chr 18|||Manual ATGTCCAAAA TCGCCCCGCA GACCCTGATG GAGGCCATCC AGGCCGTCCT GAAGGTGGACAAGGAGCGCA AGTTCAAGGA GAGCGTCGAT CTCCAGGTCA ACCTGAAGAA CTACGACCCCCAGAAGGATA AGCGTTTCTC TGGTTCCCTG AAGCTGCCGA ACGTGTGCCG CCCGCGCATGACGGTGTGCC TGCTGTGCGA CCTCGTGCAC GAGGATATCG CCAAGAAGGA GGGTGTGCCGACCATGAACC AGGAGGAGCT GAAGAAGCTC AACAAGAACA AGAAGCTGGT GAAGAAGATGTGCAACCAGT ACGACGCCTT CCTGTGCTCT GAGTCGATCA TCAAGACTGT GCCACGTCTGGTGGGCCCGC ACATGCACCG TATGGGCAAG TTTCCGACGG TGTGCTCGCC CAGCGAGTCGCTCGCAGACA AGATCGTGGA GCTGCGCTCG ACCGTGAAGT TCCAGCTGAA GAAGGTGCTGTGCCTTGGCA CCTGCGTCGG CCACATGGAG ATGAGCGAGG AGCAGCTCCG CCAGAACGTCACGATGGCGA TCAACTTCCT CGTGTCACTG CTGAAGAAGA ACTGGCAGAA CCTGAAGTCGGCGTACATCA AGTCGACGAT GGGCAAGCCG CAGCGCATCT ATTAG |
| 60S ribosomal protein L10a, putative Q4QDX9] | |
|---|---|
| Metabolite Information | |
| Molecular Function | structural constituent of ribosome |
| Biochemical Pathway | protein biosynthesis |
| Regulatory Pathway | |
| KEGG Pathways | K02865 |
| Orthologs | ||||
| Homologs | GI | Percent Identity | Evalue | Score |
| Homo sapiens | ribosomal protein L10a [Homo sapiens] | 50 | 2e-59 | 225 |
| DEG Information | ||||
| DEG Protein | DEG Organism | Percent Identity | Evalue | Bit Score |
| topA DNA topoisomerase I | Staphylococcus aureus | 47% | 4.5 | 25.4 |
| Post Translational Modification | ||||
| PTM Type | PTM Sub Type | Score | Modification Site | Prosite ID |
| Acylation | N-myristoylation site | 163-168; | PS00008 | |
| Glycosylation | N-glycosylation site | 179-182; | PS00001 | |
| Phosphorylation | cAMP- and cGMP-dependent protein kinase phosphorylation site | 44-47; | PS00004 | |
| Phosphorylation | Casein kinase II phosphorylation site | 8-11; 136-139; 140-143; | PS00006 | |
| Phosphorylation | Protein kinase C phosphorylation site | 49-51; 151-153; | PS00005 | |
| 60S ribosomal protein L10a, putative [Q4QDX9] | ||
|---|---|---|
| Model Information | ||
| Template PDB ID | 1s1iA | |
| Percent Identity | 48% | |
| Target Region | 1-214 | |
| Template Region | 4-213 | |
| Domain Information | ||
|---|---|---|
| Domains | Start | End |
| Active Site Information | ||
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| Residue | Active Site Number | Functional Part |
| Co-Factor | |
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| Metal | Description |
| Ligands | |||||
|---|---|---|---|---|---|
| CAS number | Name | Mol. Weight | Mol. Formula | Smile Notation | PDB Reference |
| Mutational Information | ||
|---|---|---|
| Residue | Feature | Description |
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| Modeled Protein | Template Structure |
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+----------<<< P R O C H E C K S U M = M A R Y >>>----------+ | = | | /var/www/html/Services/SAVES_3/jobs/712998/Q4QDX9.pdb 2.0 214 = residues | | = | *| Ramachandran plot: 87.2% core 10.3% allow 1.0% gener 1.5% = disall | | = | *| All Ramachandrans: 13 labelled residues (out of 212) = | +| Chi1-chi2 plots: 2 labelled residues (out of 140) = | | = | | Main-chain params: 6 better 0 inside 0 worse = | | Side-chain params: 5 better 0 inside 0 worse = | | = | *| Residue properties: Max.deviation: 9.6 Bad contacts: = 16 | *| Bond len/angle: 24.5 Morris et al class: 1 = 1 2 | | = | +| G-factors Dihedrals: -0.07 Covalent: -1.11 Overall: = -0.44 | | = | *| M/c bond lengths: 95.9% within limits 4.1% highlighted 6 off = graph | *| M/c bond angles: 87.3% within limits 12.7% highlighted 9 off = graph | | Planar groups: 100.0% within limits 0.0% highlighted = | | = | = +------------------------------------------------------------------------= ----+ + May be worth investigating further. * Worth investigating further. |