| Ring-box protein 1, putative [Q4QCL6] | |
|---|---|
| Systematic Name | LmjF.21.0023 [Leishmania major] |
| Gene Name | LMJF_21_0023 |
| Molecular Weight | 12107 Da |
| Protein Sequence Size | 106 |
| Function | |
| Charge | 3 |
| Isoelectric Point | 7.663 pH |
| Description | Ring-box protein 1, putative. |
| Subcellular Location | ubiquitin ligase complex[Predict] |
| E. C. Number | N.A. |
| Sequence | >tr|Q4QCL6|Q4QCL6_LEIMA Ring-box protein 1, putative - Leishmania major. QAKDEPGTSSAEEGSKGNRFQLKKWNAVALWSWDIQVDTCAICRNHIMDLCIECQSNPSC SPKDCTVAWGACNHAFHMHCISRWLKTRNVCPLDNKEWVYLRYGA |
| DNA Sequence | >LmjF21.0023 |||ring-box protein 1, putative|Leishmania major|chr 21|||Manual ATGCAGGCAA AAGACGAGCC GGGTACGTCT TCCGCGGAGG AGGGTAGCAA AGGAAACCGCTTTCAGCTGA AAAAATGGAA CGCCGTCGCG CTATGGTCCT GGGATATTCA AGTGGACACCTGCGCTATCT GTAGAAATCA CATCATGGAT CTGTGCATCG AATGCCAGTC AAATCCGTCGTGCTCGCCGA AGGACTGTAC GGTAGCGTGG GGTGCCTGCA ATCACGCCTT TCATATGCACTGCATTTCCC GATGGCTAAA GACTCGAAAC GTGTGTCCTT TAGACAATAA AGAGTGGGTTTACCTTCGAT ATGGCGCGTA A |
| Ring-box protein 1, putative Q4QCL6] | |
|---|---|
| Metabolite Information | |
| Molecular Function | ubiquitin-protein ligase activity; zinc ion binding |
| Biochemical Pathway | protein ubiquitination |
| Regulatory Pathway | |
| KEGG Pathways | K03868 |
| Orthologs | ||||
| Homologs | GI | Percent Identity | Evalue | Score |
| Homo sapiens | ring-box 1 [Homo sapiens] | 67 | 2e-41 | 163 |
| DEG Information | ||||
| DEG Protein | DEG Organism | Percent Identity | Evalue | Bit Score |
| YOL133w finger protein | Saccharomyces cerevisiae | 56% | 1e-34 | 137 |
| Post Translational Modification | ||||
| PTM Type | PTM Sub Type | Score | Modification Site | Prosite ID |
| PDOC00449 | Zinc finger RING-type signature and profile | 9.465 | 52-96 | PS50089 |
| Acylation | N-myristoylation site | 8-13; 15-20; | PS00008 | |
| Phosphorylation | Casein kinase II phosphorylation site | 10-13; 11-14; 62-65; | PS00006 | |
| Phosphorylation | Protein kinase C phosphorylation site | 62-64; | PS00005 | |
| Ring-box protein 1, putative [Q4QCL6] | ||
|---|---|---|
| Model Information | ||
| Template PDB ID | 2hyeD | |
| Percent Identity | 67% | |
| Target Region | 18-106 | |
| Template Region | 19-90 | |
| Domain Information | ||
|---|---|---|
| Domains | Start | End |
| Active Site Information | ||
|---|---|---|
| Residue | Active Site Number | Functional Part |
| Co-Factor | |
|---|---|
| Metal | Description |
| Ligands | |||||
|---|---|---|---|---|---|
| CAS number | Name | Mol. Weight | Mol. Formula | Smile Notation | PDB Reference |
| 23713-49-7 | ZINC ION | 65.409 | Zn | [Zn+2] | 2hye |
| Mutational Information | ||
|---|---|---|
| Residue | Feature | Description |
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| Modeled Protein | Template Structure |
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+----------<<< P R O C H E C K S U M = M A R Y >>>----------+ | = | | /var/www/html/Services/SAVES_3/jobs/3166824/Q4QCL6.pdb 2.0 89 = residues | | = | *| Ramachandran plot: 73.2% core 22.0% allow 4.9% gener 0.0% = disall | | = | *| All Ramachandrans: 8 labelled residues (out of 87) = | +| Chi1-chi2 plots: 1 labelled residues (out of 58) = | | = | +| Main-chain params: 5 better 0 inside 1 worse = | | Side-chain params: 5 better 0 inside 0 worse = | | = | *| Residue properties: Max.deviation: 20.1 Bad contacts: = 2 | *| Bond len/angle: 7.6 Morris et al class: 2 = 1 3 | | = | +| G-factors Dihedrals: -0.40 Covalent: -0.61 Overall: = -0.46 | | = | | M/c bond lengths: 98.9% within limits 1.1% highlighted = | | M/c bond angles: 85.8% within limits 14.2% highlighted = | | Planar groups: 100.0% within limits 0.0% highlighted = | | = | = +------------------------------------------------------------------------= ----+ + May be worth investigating further. * Worth investigating further. |