| Centrin, putative [Q4QBK6] | |
|---|---|
| Systematic Name | LmjF.22.1410 [Leishmania major] |
| Gene Name | LMJF_22_1410 |
| Molecular Weight | 16448 Da |
| Protein Sequence Size | 149 |
| Function | |
| Charge | -14.5 |
| Isoelectric Point | 4.1552 pH |
| Description | Centrin, putative (Ca2+-binding ef-hand protein). |
| Subcellular Location | basal body[Predict] |
| E. C. Number | N.A. |
| Sequence | >tr|Q4QBK6|Q4QBK6_LEIMA Centrin, putative (Ca2+-binding ef-hand protein) - Leishmania major AALTDEQIREAFNLFDADGSGAIDAEEMALAMKGLGFGDLSRDEVERIIRSMHTDSNGLV AYGEFEAMVKSRMAQKDSPEEILKAFQLFDLDKKGKISFANLKEVAKLLGENPGDDVLKE MIAEADEDGDGEVSFEEFKSVMLQMRGK |
| DNA Sequence | >LmjF22.1410 |||centrin, putative|Leishmania major|chr 22|||Manual ATGGCTGCGC TTACGGATGA GCAGATTCGC GAGGCCTTCA ACCTCTTCGA CGCCGACGGCTCTGGGGCTA TCGACGCGGA GGAGATGGCG CTAGCGATGA AGGGTCTCGG CTTCGGTGACCTGTCGCGCG ACGAGGTGGA GCGCATTATC CGCTCCATGC ACACAGACTC CAACGGCCTGGTGGCGTACG GCGAGTTTGA AGCCATGGTC AAGTCGCGCA TGGCGCAGAA GGACTCGCCGGAGGAGATCC TAAAGGCCTT TCAGCTCTTC GACCTCGATA AGAAAGGAAA AATCTCCTTTGCGAACTTGA AGGAGGTTGC GAAACTGCTG GGTGAGAACC CCGGCGACGA TGTGCTGAAGGAGATGATCG CCGAGGCCGA TGAGGACGGT GATGGCGAGG TTTCCTTTGA GGAGTTCAAGAGCGTGATGC TGCAGATGCG TGGAAAGTAG |
| Centrin, putative Q4QBK6] | |
|---|---|
| Metabolite Information | |
| Molecular Function | calcium ion binding |
| Biochemical Pathway | biological process unknown |
| Regulatory Pathway | |
| KEGG Pathways | |
| Orthologs | ||||
| Homologs | GI | Percent Identity | Evalue | Score |
| Homo sapiens | caltractin [Homo sapiens] | 53 | 5e-36 | 146 |
| DEG Information | ||||
| DEG Protein | DEG Organism | Percent Identity | Evalue | Bit Score |
| YOR257w spindle pole body component, centrin | Saccharomyces cerevisiae | 41% | 8e-25 | 106 |
| Post Translational Modification | ||||
| PTM Type | PTM Sub Type | Score | Modification Site | Prosite ID |
| PDOC00018 | EF-hand calcium-binding domain signature and profile | 17-29; 127-139; | PS00018 | |
| PDOC00018 | EF-hand calcium-binding domain signature and profile | 15.713; 7.065; 14.123; 14.541 | 4-39; 41-76; 78-113; 114-149 | PS50222 |
| Acylation | N-myristoylation site | 22-27; 35-40; | PS00008 | |
| Phosphorylation | Casein kinase II phosphorylation site | 42-45; 79-82; 135-138; | PS00006 | |
| Centrin, putative [Q4QBK6] | ||
|---|---|---|
| Model Information | ||
| Template PDB ID | 2ggmB | |
| Percent Identity | 53% | |
| Target Region | 1-149 | |
| Template Region | 25-144 | |
| Domain Information | ||
|---|---|---|
| Domains | Start | End |
| Active Site Information | ||
|---|---|---|
| Residue | Active Site Number | Functional Part |
| Co-Factor | |
|---|---|
| Metal | Description |
| Ligands | |||||
|---|---|---|---|---|---|
| CAS number | Name | Mol. Weight | Mol. Formula | Smile Notation | PDB Reference |
| 17787-72-3 | CALCIUM ION | 40.078 | Ca | [Ca+2] | 2ggm |
| Mutational Information | ||
|---|---|---|
| Residue | Feature | Description |
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| Modeled Protein | Template Structure |
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+----------<<< P R O C H E C K S U M = M A R Y >>>----------+ | = | | /var/www/html/Services/SAVES_3/jobs/757401/Q4QBK6.pdb 2.0 149 = residues | | = | +| Ramachandran plot: 93.2% core 6.1% allow 0.8% gener 0.0% = disall | | = | +| All Ramachandrans: 1 labelled residues (out of 147) = | | Chi1-chi2 plots: 0 labelled residues (out of 100) = | | = | | Main-chain params: 6 better 0 inside 0 worse = | | Side-chain params: 5 better 0 inside 0 worse = | | = | | Residue properties: Max.deviation: 2.5 Bad contacts: = 4 | +| Bond len/angle: 4.0 Morris et al class: 1 = 1 2 | | = | | G-factors Dihedrals: 0.24 Covalent: -0.08 Overall: = 0.12 | | = | | M/c bond lengths: 99.6% within limits 0.4% highlighted = | | M/c bond angles: 94.8% within limits 5.2% highlighted = | | Planar groups: 100.0% within limits 0.0% highlighted = | | = | = +------------------------------------------------------------------------= ----+ + May be worth investigating further. * Worth investigating further. |