| Rev7, putative [Q4Q9S3] | |
|---|---|
| Systematic Name | LmjF.25.1670 [Leishmania major] |
| Gene Name | LMJF_25_1670 |
| Molecular Weight | 22437 Da |
| Protein Sequence Size | 201 |
| Function | |
| Charge | -5 |
| Isoelectric Point | 4.9 pH |
| Description | Rev7, putative (Mitotic spindle checkpoint component, putative). |
| Subcellular Location | nucleus[Predict] |
| E. C. Number | N.A. |
| Sequence | >tr|Q4Q9S3|Q4Q9S3_LEIMA Rev7, putative (Mitotic spindle checkpoint component, putative) - Leishmania major TQTTHAISLTGSVATVTEYLGFAINNILYQRGVYPPDNFQQVKKFGLSLMISADADLNAY LAELLQQISSWIAHGTCRRLVMLITDVPSVQTLERWEINIETEPAASSSRLHGSGRKSEE DVRMEIQAVMRQITACVSFLPVITQPCAFDLLVYTSADAQVPSTAWEPSDPQVLERGTEV KLRSFTTSFHYVDTSVVYRE |
| DNA Sequence | >LmjF25.1670 |||rev7, putative|Leishmania major|chr 25|||Manual ATGACGCAGA CGACTCACGC CATCTCCCTC ACCGGCTCCG TCGCCACCGT CACGGAGTACCTCGGCTTTG CCATTAATAA TATTCTCTAC CAGCGAGGTG TCTACCCGCC AGACAACTTCCAGCAAGTGA AGAAGTTCGG TCTGTCGCTC ATGATCTCCG CCGATGCGGA TTTGAACGCGTACCTGGCGG AGCTTCTACA GCAGATTTCG TCTTGGATTG CGCACGGAAC GTGCCGGCGTCTGGTGATGC TTATTACCGA CGTTCCGTCA GTGCAGACGC TGGAGCGGTG GGAAATCAACATAGAAACAG AGCCCGCAGC GTCGTCGTCG CGCCTACACG GCAGCGGTCG CAAGAGCGAGGAGGACGTTC GCATGGAGAT TCAAGCCGTG ATGCGGCAGA TCACCGCCTG CGTGTCCTTCCTGCCTGTGA TCACGCAGCC GTGTGCCTTC GACCTGCTCG TTTACACATC TGCAGACGCGCAGGTGCCGT CGACAGCGTG GGAGCCGAGC GACCCGCAAG TGCTCGAGCG CGGCACCGAAGTCAAGCTGC GCTCCTTCAC CACGTCCTTC CACTACGTCG ACACGAGTGT GGTCTATCGTGAGTGA |
| Rev7, putative Q4Q9S3] | |
|---|---|
| Metabolite Information | |
| Molecular Function | DNA binding |
| Biochemical Pathway | mitotic spindle checkpoint |
| Regulatory Pathway | |
| KEGG Pathways | K02537 |
| Orthologs | ||||
| Homologs | GI | Percent Identity | Evalue | Score |
| Homo sapiens | MAD2-like 1 [Homo sapiens] | 41 | 3e-42 | 168 |
| DEG Information | ||||
| DEG Protein | DEG Organism | Percent Identity | Evalue | Bit Score |
| pyrH Uridylate kinase (EC 2.7.4.-) | Escherichia coli MG1655 | 41% | 2.4 | 26.2 |
| Post Translational Modification | ||||
| PTM Type | PTM Sub Type | Score | Modification Site | Prosite ID |
| PDOC50815 | HORMA domain profile | 37.714 | 11-197 | PS50815 |
| Acylation | N-myristoylation site | 12-17; | PS00008 | |
| Amidation | Amidation site | 115-118; | PS00009 | |
| Phosphorylation | Casein kinase II phosphorylation site | 16-19; 119-122; 156-159; 165-168; | PS00006 | |
| Phosphorylation | Protein kinase C phosphorylation site | 77-79; 109-111; 115-117; | PS00005 | |
| Rev7, putative [Q4Q9S3] | ||
|---|---|---|
| Model Information | ||
| Template PDB ID | 2v64H | |
| Percent Identity | 43% | |
| Target Region | 6-193 | |
| Template Region | 9-179 | |
| Domain Information | ||
|---|---|---|
| Domains | Start | End |
| Active Site Information | ||
|---|---|---|
| Residue | Active Site Number | Functional Part |
| Co-Factor | |
|---|---|
| Metal | Description |
| Ligands | |||||
|---|---|---|---|---|---|
| CAS number | Name | Mol. Weight | Mol. Formula | Smile Notation | PDB Reference |
| Mutational Information | ||
|---|---|---|
| Residue | Feature | Description |
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| Modeled Protein | Template Structure |
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+----------<<< P R O C H E C K S U M = M A R Y >>>----------+ | = | | /var/www/html/Services/SAVES_3/jobs/732375/Q4Q9S3.pdb 2.0 188 = residues | | = | *| Ramachandran plot: 89.9% core 7.1% allow 2.4% gener 0.6% = disall | | = | +| All Ramachandrans: 5 labelled residues (out of 186) = | | Chi1-chi2 plots: 0 labelled residues (out of 104) = | | = | | Main-chain params: 6 better 0 inside 0 worse = | | Side-chain params: 5 better 0 inside 0 worse = | | = | *| Residue properties: Max.deviation: 4.0 Bad contacts: = 5 | *| Bond len/angle: 8.9 Morris et al class: 1 = 1 2 | | = | | G-factors Dihedrals: 0.06 Covalent: -0.21 Overall: = -0.04 | | = | | M/c bond lengths: 99.1% within limits 0.9% highlighted = | *| M/c bond angles: 93.2% within limits 6.8% highlighted 1 off = graph | | Planar groups: 100.0% within limits 0.0% highlighted = | | = | = +------------------------------------------------------------------------= ----+ + May be worth investigating further. * Worth investigating further. |