| Ribose 5-phosphate isomerase, putative [Q4Q869] | |
|---|---|
| Systematic Name | LmjF.28.1970 [Leishmania major] |
| Gene Name | LMJF_28_1970 |
| Molecular Weight | 18617 Da |
| Protein Sequence Size | 172 |
| Function | |
| Charge | 0 |
| Isoelectric Point | 6.4 pH |
| Description | Ribose 5-phosphate isomerase, putative (EC 5.3.1.6). |
| Subcellular Location | N.A.[Predict] |
| E. C. Number | 5.3.1.6 |
| Sequence | >tr|Q4Q869|Q4Q869_LEIMA Ribose 5-phosphate isomerase, putative (EC 5.3.1.6) - Leishmania major SKRVALGCDHAAYAAHREIMDMISASGAVSKVMYMGPSSDTSVDYPDYAAQVCEAILKGE ADAGILVCGTGIGMSIAANKFRGIRAALCYDHVTAQLSRQHNNAHILCIGVRTSGMEIIR DIITTFLTTEPLAEGRHSNRVDKITVIEEEQMKDEQRCCFSGCGGRKEEGK |
| DNA Sequence | >LmjF28.1970 |||ribose 5-phosphate isomerase, putative|Leishmania major|chr 28|||Manual ATGTCGAAGC GTGTTGCTCT GGGCTGTGAC CACGCCGCCT ACGCCGCACA TCGGGAGATCATGGACATGA TCAGCGCCAG CGGTGCTGTG TCAAAGGTGA TGTACATGGG CCCCTCCTCCGACACATCCG TCGACTACCC CGACTACGCC GCGCAGGTGT GTGAGGCCAT CTTGAAGGGCGAGGCGGATG CGGGCATCCT CGTCTGCGGA ACCGGCATCG GCATGTCGAT CGCGGCCAACAAGTTCAGAG GCATTCGTGC GGCGCTTTGC TACGACCACG TGACGGCGCA GCTGAGCCGCCAGCACAACA ACGCTCACAT CTTGTGCATT GGGGTGCGCA CCAGTGGCAT GGAGATCATCCGCGACATCA TCACGACCTT CCTCACGACA GAGCCGTTGG CAGAAGGGCG CCACAGCAACCGCGTCGATA AGATCACGGT GATCGAGGAG GAGCAGATGA AGGACGAACA GCGATGCTGCTTCAGCGGTT GTGGAGGCCG TAAGGAAGAA GGAAAGTGA |
| Ribose 5-phosphate isomerase, putative Q4Q869] | |
|---|---|
| Metabolite Information | |
| Molecular Function | ribose-5-phosphate isomerase activity |
| Biochemical Pathway | carbohydrate metabolism; pentose-phosphate shunt; pentose-phosphate shunt, non-oxidative branch; |
| Regulatory Pathway | |
| KEGG Pathways | K01808 |
| Orthologs | ||||
| Homologs | GI | Percent Identity | Evalue | Score |
| Homo sapiens | apical protein of Xenopus-like [Homo sapiens] | 28 | 2.3 | 29 |
| DEG Information | ||||
| DEG Protein | DEG Organism | Percent Identity | Evalue | Bit Score |
| HP0574 galactosidase acetyltransferase (lacA) | Helicobacter pylori | 50% | 5e-27 | 114 |
| Post Translational Modification | ||||
| PTM Type | PTM Sub Type | Score | Modification Site | Prosite ID |
| Acylation | N-myristoylation site | 8-13; 65-70; 70-75; 72-77; 74-79; 84-89; 111-116; | PS00008 | |
| Amidation | Amidation site | 165-168; | PS00009 | |
| Phosphorylation | Casein kinase II phosphorylation site | 42-45; 115-118; 146-149; | PS00006 | |
| Phosphorylation | Protein kinase C phosphorylation site | 2-4; 139-141; | PS00005 | |
| Sulfation | Tyrosine sulfation site | 39-53; | PS00003 | |
| Ribose 5-phosphate isomerase, putative [Q4Q869] | ||
|---|---|---|
| Model Information | ||
| Template PDB ID | 1nn4D | |
| Percent Identity | 44% | |
| Target Region | 1-162 | |
| Template Region | 1-159 | |
| Domain Information | ||
|---|---|---|
| Domains | Start | End |
| Active Site Information | ||
|---|---|---|
| Residue | Active Site Number | Functional Part |
| Asp | 10 | Side Chain |
| His | 11 | Side Chain |
| Cys | 69 | Side Chain |
| Arg | 141 | Side Chain |
| Co-Factor | |
|---|---|
| Metal | Description |
| Ligands | |||||
|---|---|---|---|---|---|
| CAS number | Name | Mol. Weight | Mol. Formula | Smile Notation | PDB Reference |
| Mutational Information | ||
|---|---|---|
| Residue | Feature | Description |
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| Modeled Protein | Template Structure |
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+----------<<< P R O C H E C K S U M = M A R Y >>>----------+ | = | | /var/www/html/Services/SAVES_3/jobs/3799800/Q4Q869.pdb 2.0 151 = residues | | = | *| Ramachandran plot: 94.8% core 4.5% allow 0.0% gener 0.7% = disall | | = | +| All Ramachandrans: 3 labelled residues (out of 149) = | +| Chi1-chi2 plots: 1 labelled residues (out of 82) = | | = | | Main-chain params: 6 better 0 inside 0 worse = | | Side-chain params: 5 better 0 inside 0 worse = | | = | *| Residue properties: Max.deviation: 4.0 Bad contacts: = 4 | *| Bond len/angle: 8.2 Morris et al class: 1 = 1 2 | +| 1 cis-peptides = | | G-factors Dihedrals: 0.11 Covalent: -0.09 Overall: = 0.03 | | = | | M/c bond lengths: 99.7% within limits 0.3% highlighted = | | M/c bond angles: 96.0% within limits 4.0% highlighted = | | Planar groups: 100.0% within limits 0.0% highlighted = | | = | = +------------------------------------------------------------------------= ----+ + May be worth investigating further. * Worth investigating further. |