| Hypothetical protein [Q4Q7M2] | |
|---|---|
| Systematic Name | LmjF.30.0810 [Leishmania major] |
| Gene Name | LMJF_30_0810 |
| Molecular Weight | 28157 Da |
| Protein Sequence Size | 250 |
| Function | |
| Charge | -1 |
| Isoelectric Point | 6.2539 pH |
| Description | Hypothetical protein. |
| Subcellular Location | N.A.[Predict] |
| E. C. Number | N.A. |
| Sequence | >tr|Q4Q7M2|Q4Q7M2_LEIMA Hypothetical protein - Leishmania major PSKEASSRNLPISGRDTNGKTYRSTDEMWKAELTGDLYDPEKGWYGKALEYWRTVPATVS GVLGGMDHVHDVDIEGSRNFIASLPGHGTSRALDCGAGIGRITKNLLTKLYATTDLLEPV KHMLEEAKRELAGMPVGKFILASMETATLPPNTYDLIVIQWTAIYLTDADFVKFFKHCQQ ALTPNGYIFFKENCSTGDRFLVDKEDSSLTRSDIHYKRLFNESGVRVVKEAFQEEWPTDL FPLKMYALK |
| DNA Sequence | >LmjF30.0810 |||hypothetical protein, conserved|Leishmania major|chr 30|||Manual ATGCCGAGCA AGGAGGCGTC GTCGCGCAAC CTGCCGATCA GCGGCCGCGA CACGAACGGTAAGACGTACC GCTCCACGGA TGAAATGTGG AAAGCGGAGC TGACGGGCGA CCTGTACGACCCCGAGAAGG GATGGTACGG CAAGGCACTC GAGTACTGGC GCACCGTTCC TGCGACGGTGAGCGGTGTGC TGGGCGGCAT GGATCATGTC CATGACGTGG ACATTGAAGG GTCTCGCAACTTCATTGCGA GCTTGCCAGG CCACGGAACA AGCCGTGCGT TGGACTGCGG CGCCGGCATTGGGAGGATTA CGAAGAACTT GCTGACGAAA CTGTACGCCA CGACGGACTT GCTGGAGCCGGTGAAGCACA TGCTGGAGGA GGCCAAAAGG GAGCTGGCCG GCATGCCCGT TGGCAAGTTCATTTTAGCGT CTATGGAGAC GGCAACGCTT CCACCAAACA CATACGACCT GATTGTGATCCAGTGGACCG CGATCTACCT CACCGACGCC GACTTTGTGA AGTTCTTCAA GCACTGTCAACAGGCCTTGA CGCCGAACGG GTACATCTTT TTCAAGGAGA ACTGCTCCAC TGGTGACCGCTTCCTTGTGG ATAAGGAGGA CAGTAGCCTG ACGCGGTCCG ACATACACTA CAAGCGACTCTTCAATGAGA GCGGGGTGCG AGTGGTGAAA GAAGCTTTCC AGGAGGAGTG GCCGACAGACTTGTTCCCTT TGAAGATGTA CGCGCTCAAG TAG |
| Hypothetical protein Q4Q7M2] | |
|---|---|
| Metabolite Information | |
| Molecular Function | S-adenosylmethionine-dependent methyltransferase activity; methyltransferase activity |
| Biochemical Pathway | biological process unknown |
| Regulatory Pathway | |
| KEGG Pathways | |
| Orthologs | ||||
| Homologs | GI | Percent Identity | Evalue | Score |
| Homo sapiens | hypothetical protein LOC28989 [Homo sapiens] | 35 | 1e-35 | 147 |
| DEG Information | ||||
| DEG Protein | DEG Organism | Percent Identity | Evalue | Bit Score |
| safC papC-like porin protein (fimbrial biogenesis) | Salmonella typhimurium | 36% | 3.3 | 26.2 |
| Post Translational Modification | ||||
| PTM Type | PTM Sub Type | Score | Modification Site | Prosite ID |
| PDOC00017 | ATP/GTP-binding site motif A (P-loop) | 15-22; | PS00017 | |
| PDOC00029 | Leucine zipper pattern | 111-132; | PS00029 | |
| Acylation | N-myristoylation site | 62-67; 89-94; 97-102; 134-139; | PS00008 | |
| Glycosylation | N-glycosylation site | 194-197; 222-225; | PS00001 | |
| Phosphorylation | Casein kinase II phosphorylation site | 14-17; 25-28; 168-171; 196-199; 211-214; | PS00006 | |
| Phosphorylation | Protein kinase C phosphorylation site | 7-9; 14-16; 22-24; 90-92; | PS00005 | |
| Sulfation | Tyrosine sulfation site | 32-46; | PS00003 | |
| Hypothetical protein [Q4Q7M2] | ||
|---|---|---|
| Model Information | ||
| Template PDB ID | 1xtpA | |
| Percent Identity | 100% | |
| Target Region | 1-250 | |
| Template Region | 1-246 | |
| Domain Information | ||
|---|---|---|
| Domains | Start | End |
| Active Site Information | ||
|---|---|---|
| Residue | Active Site Number | Functional Part |
| ILE | 165 | Sidechain |
| Co-Factor | |
|---|---|
| Metal | Description |
| Ligands | |||||
|---|---|---|---|---|---|
| CAS number | Name | Mol. Weight | Mol. Formula | Smile Notation | PDB Reference |
| S-ADENOSYL-L-HOMOSELENOCYSTEINE | 431.306 | C14 H20 N6 O5 Se | O=C(O)C(N)CC[Se]CC3OC(n2cnc1c(ncnc12)N)C(O)C3O | 1xtp | |
| Mutational Information | ||
|---|---|---|
| Residue | Feature | Description |
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| Modeled Protein | Template Structure |
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+----------<<< P R O C H E C K S U M = M A R Y >>>----------+ | = | | /var/www/html/Services/SAVES_3/jobs/4774876/Q4Q7M2.pdb 2.0 250 = residues | | = | +| Ramachandran plot: 94.9% core 4.6% allow 0.5% gener 0.0% = disall | | = | +| All Ramachandrans: 3 labelled residues (out of 248) = | +| Chi1-chi2 plots: 1 labelled residues (out of 151) = | | = | | Main-chain params: 6 better 0 inside 0 worse = | | Side-chain params: 5 better 0 inside 0 worse = | | = | *| Residue properties: Max.deviation: 3.7 Bad contacts: = 1 | *| Bond len/angle: 8.3 Morris et al class: 1 = 1 2 | | = | | G-factors Dihedrals: 0.12 Covalent: -0.18 Overall: = 0.01 | | = | | M/c bond lengths: 98.8% within limits 1.2% highlighted = | | M/c bond angles: 93.5% within limits 6.5% highlighted = | +| Planar groups: 98.9% within limits 1.1% highlighted 1 off = graph | | = | = +------------------------------------------------------------------------= ----+ + May be worth investigating further. * Worth investigating further. |