| Hypothetical protein [Q4Q7A6] | |
|---|---|
| Systematic Name | LmjF.30.1890 [Leishmania major] |
| Gene Name | LMJF_30_1890 |
| Molecular Weight | 20934 Da |
| Protein Sequence Size | 180 |
| Function | |
| Charge | -18.5 |
| Isoelectric Point | 4.2936 pH |
| Description | Hypothetical protein. |
| Subcellular Location | N.A.[Predict] |
| E. C. Number | N.A. |
| Sequence | >tr|Q4Q7A6|Q4Q7A6_LEIMA Hypothetical protein - Leishmania major EQPKGINILITGTPGTGKTSMAEMIAAELDGFQHLEVGKLVKENHFYTEYDTELDTHIIE EKDEDRLLDFMEPIMVSRGNHVVDYHSSELFPERWFHMVVVLHTSTEVLFERLTKRQYSE AKRAENMEAEIQCICEEEARDAYEDDIVLVRENDTLEQMAATVEEIRERVEVLKVERGL |
| DNA Sequence | >LmjF30.1890 |||hypothetical protein, conserved|Leishmania major|chr 30|||Manual ATGGAGCAAC CAAAAGGCAT CAACATCCTC ATCACCGGCA CCCCCGGAAC GGGGAAGACTTCGATGGCGG AGATGATCGC CGCGGAGCTG GACGGCTTTC AGCACCTGGA GGTGGGTAAGCTTGTGAAAG AGAACCACTT CTACACTGAG TACGACACGG AGCTGGACAC GCACATTATCGAGGAGAAGG ACGAGGATCG CCTTCTCGAT TTTATGGAGC CCATCATGGT GAGTCGGGGCAACCACGTCG TCGATTATCA CTCCAGCGAG CTGTTTCCCG AGCGCTGGTT CCACATGGTGGTTGTGCTCC ACACATCCAC GGAGGTTCTG TTTGAGCGCC TGACCAAGCG GCAGTACAGCGAGGCGAAGC GAGCGGAGAA CATGGAGGCT GAGATTCAGT GTATCTGCGA GGAGGAGGCGCGCGACGCCT ACGAGGATGA CATTGTGCTG GTTCGCGAGA ACGACACTTT GGAGCAGATGGCGGCTACGG TGGAAGAGAT TCGCGAGCGG GTGGAGGTGC TAAAGGTCGA GCGCGGCCTCTGA |
| Hypothetical protein Q4Q7A6] | |
|---|---|
| Metabolite Information | |
| Molecular Function | ATP binding; shikimate kinase activity |
| Biochemical Pathway | amino acid biosynthesis |
| Regulatory Pathway | |
| KEGG Pathways | |
| Orthologs | ||||
| Homologs | GI | Percent Identity | Evalue | Score |
| Homo sapiens | TAF9 RNA polymerase II isoform b [Homo sapiens] | 38 | 5e-27 | 117 |
| DEG Information | ||||
| DEG Protein | DEG Organism | Percent Identity | Evalue | Bit Score |
| YDL166c unknown/ | Saccharomyces cerevisiae | 35% | 4e-26 | 111 |
| Post Translational Modification | ||||
| PTM Type | PTM Sub Type | Score | Modification Site | Prosite ID |
| PDOC00017 | ATP/GTP-binding site motif A (P-loop) | 13-20; | PS00017 | |
| Acylation | N-myristoylation site | 13-18; 16-21; | PS00008 | |
| Glycosylation | N-glycosylation site | 154-157; | PS00001 | |
| Phosphorylation | Casein kinase II phosphorylation site | 21-24; 49-52; 53-56; 105-108; 163-166; | PS00006 | |
| Phosphorylation | Protein kinase C phosphorylation site | 17-19; 115-117; | PS00005 | |
| Phosphorylation | Tyrosine kinase phosphorylation site | 40-48; | PS00007 | |
| Sulfation | Tyrosine sulfation site | 44-58; 137-151; | PS00003 | |
| Hypothetical protein [Q4Q7A6] | ||
|---|---|---|
| Model Information | ||
| Template PDB ID | 1y63A | |
| Percent Identity | 93% | |
| Target Region | 1-184 | |
| Template Region | 6-168 | |
| Domain Information | ||
|---|---|---|
| Domains | Start | End |
| Active Site Information | ||
|---|---|---|
| Residue | Active Site Number | Functional Part |
| Co-Factor | |
|---|---|
| Metal | Description |
| Ligands | |||||
|---|---|---|---|---|---|
| CAS number | Name | Mol. Weight | Mol. Formula | Smile Notation | PDB Reference |
| 58-64-0 | ADENOSINE-5'-DIPHOSPHATE | 427.201 | C10 H15 N5 O10 P2 | O=P(O)(O)OP(=O)(O)OCC3OC(n2cnc1c(ncnc12)N)C(O)C3O | 1y63 |
| 24959-67-9 | BROMIDE ION | 79.904 | Br | [Br-] | 1y63 |
| 16397-91-4 | MANGANESE (II) ION | 54.938 | Mn | [Mn+2] | 1y63 |
| 7440-23-5 | SODIUM ION | 22.99 | Na | [Na+] | 1y63 |
| Mutational Information | ||
|---|---|---|
| Residue | Feature | Description |
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| Modeled Protein | Template Structure |
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+----------<<< P R O C H E C K S U M = M A R Y >>>----------+ | = | | /var/www/html/Services/SAVES_3/jobs/702650/Q4Q7A6.pdb 2.0 180 = residues | | = | | Ramachandran plot: 97.6% core 2.4% allow 0.0% gener 0.0% = disall | | = | +| All Ramachandrans: 1 labelled residues (out of 178) = | | Chi1-chi2 plots: 0 labelled residues (out of 123) = | | = | | Main-chain params: 6 better 0 inside 0 worse = | | Side-chain params: 5 better 0 inside 0 worse = | | = | *| Residue properties: Max.deviation: 2.8 Bad contacts: = 2 | *| Bond len/angle: 5.5 Morris et al class: 1 = 1 2 | | = | | G-factors Dihedrals: 0.17 Covalent: -0.09 Overall: = 0.07 | | = | | M/c bond lengths: 99.3% within limits 0.7% highlighted = | | M/c bond angles: 95.0% within limits 5.0% highlighted = | | Planar groups: 100.0% within limits 0.0% highlighted = | | = | = +------------------------------------------------------------------------= ----+ + May be worth investigating further. * Worth investigating further. |