LeishBase: Leishmania Structural Database
header
Home List of Proteins How to Visualize Structures Download Contact Us
Succinyl-coa:3-ketoacid-coenzyme a transferase-like protein [Q4Q7A2]
Systematic NameLmjF.30.1940 [Leishmania major]
Gene NameLMJF_30_1940
Molecular Weight53529 Da
Protein Sequence Size499
Function
Charge4.5
Isoelectric Point7.3 pH
DescriptionSuccinyl-coa:3-ketoacid-coenzyme a transferase-like protein.
Subcellular LocationN.A.[Predict]
E. C. Number N.A.
Sequence>tr|Q4Q7A2|Q4Q7A2_LEIMA Succinyl-coa:3-ketoacid-coenzyme a transferase-like protein - Leishmania major
LRHTRRAFRPRVMSAAESVQDIHDGATIAGGGFGFCGFPFELFDAVNATKAKNLTVIGAT
MGGVDSGFGPLARDGQLKKAITTYVGENPLFTQHLFHGEFEVEFCPMGTLVDRLRAAGAG
LPAFYTPTGYGTAVAEGRLPVRFAPGKPVRVAEYSQPRETRQFNGRWCTLEMALPADFAL
VRAWKADRRGNLVFRGTTQNFNLASAKAAKVCIAEVEEIVECGELDPKTVHLPGVYVHRL
VCPPNIRRAAEFVVERKPGFSTGTGKNAHASRNLIARRAALEIKDGMTLNLGIGIPNMVA
SYIPPEMDVVLQGENGLLGIGPYPLPEEVDPDITNAGKQTITMSKSGASLFDSAESFSMI
RGGHLDLTMLGALEVSGTGDIASWWIPGKLLKGMGGAMDLVVCGCKTIVLMEHTDREGKS
RIVENCRAPVTGRDCVEMIITDLAVFVVKKAAGGVRSLVLTEIAEGLTVEEVKLKTEAPF
AVSADLKTMPLAPVPSQV
DNA Sequence>LmjF30.1940 |||succinyl-coa:3-ketoacid-coenzyme a transferase-like protein|Leishmania major|chr 30|||Manual
ATGCTGCGCC ATACACGTCG GGCCTTCCGG CCGAGGGTGA TGAGTGCCGC CGAGTCTGTCCAGGACATTC ACGATGGTGC CACCATCGCG GGCGGTGGTT TTGGTTTTTG CGGCTTCCCGTTCGAGCTGT TCGACGCCGT CAACGCCACC AAGGCGAAGA ACCTCACGGT GATTGGGGCGACAATGGGCG GTGTGGACAG CGGCTTTGGT CCGCTTGCGC GAGACGGGCA GCTAAAGAAGGCCATCACCA CCTACGTTGG CGAGAACCCG CTGTTCACGC AGCACCTCTT TCACGGCGAGTTCGAGGTGG AGTTTTGCCC CATGGGCACG TTGGTGGACC GGCTGCGCGC TGCGGGTGCCGGGCTGCCCG CCTTCTACAC CCCCACCGGC TACGGCACAG CGGTAGCCGA GGGCCGCCTCCCTGTGCGCT TTGCGCCGGG CAAGCCCGTG AGGGTGGCCG AGTACAGCCA GCCACGCGAGACGCGGCAGT TCAACGGGCG GTGGTGCACG CTGGAGATGG CGCTGCCAGC GGACTTTGCGCTTGTGCGCG CGTGGAAGGC GGACAGGCGC GGCAACCTCG TGTTCCGCGG GACAACGCAGAACTTTAACC TTGCGTCCGC GAAGGCTGCG AAGGTGTGCA TCGCGGAGGT GGAGGAGATTGTGGAGTGCG GGGAGCTAGA CCCGAAGACG GTGCACCTGC CCGGCGTGTA TGTGCACCGCCTGGTGTGCC CACCGAACAT CAGGAGAGCC GCCGAGTTCG TGGTGGAGCG CAAGCCCGGGTTCTCGACGG GGACGGGGAA GAACGCGCAT GCAAGCCGCA ATCTCATAGC TCGCCGCGCAGCCCTTGAGA TCAAGGATGG CATGACTCTG AACCTTGGCA TTGGCATCCC CAACATGGTGGCGAGCTACA TTCCGCCGGA GATGGACGTG GTGCTGCAGG GAGAAAACGG CTTACTCGGCATTGGCCCCT ACCCGCTGCC GGAGGAGGTG GACCCCGACA TCACTAACGC CGGCAAGCAGACTATCACCA TGAGCAAGTC AGGCGCTTCG CTGTTCGACA GCGCCGAGTC CTTCAGCATGATTCGCGGTG GCCATTTGGA CTTGACGATG CTTGGCGCGC TGGAGGTCTC TGGCACCGGCGACATTGCCA GCTGGTGGAT ACCTGGCAAG CTGCTGAAGG GCATGGGTGG CGCCATGGATCTGGTGGTGT GCGGTTGCAA GACAATCGTG TTGATGGAGC ACACGGACAG GGAGGGTAAGTCGCGCATCG TTGAGAACTG CAGGGCACCC GTCACGGGTC GTGATTGCGT TGAGATGATTATCACGGATC TGGCCGTCTT TGTTGTGAAG AAGGCGGCTG GAGGTGTGAG GTCGCTGGTCTTGACGGAGA TTGCCGAGGG TTTGACGGTG GAGGAGGTAA AGCTCAAGAC TGAGGCACCCTTCGCCGTGT CTGCGGACCT CAAGACGATG CCGTTGGCGC CTGTTCCAAG TCAAGTGTAG
Succinyl-coa:3-ketoacid-coenzyme a transferase-like protein Q4Q7A2]
Metabolite Information
Molecular FunctionCoA-transferase activity
Biochemical Pathwaymetabolism
Regulatory Pathway
KEGG PathwaysK01029
Orthologs
Homologs GI Percent Identity Evalue Score
Homo sapiens3-oxoacid CoA transferase 1 precursor [Homo sapiens]451e-110395
DEG Information
DEG Protein DEG Organism Percent Identity Evalue Bit Score
atoA acetate CoA-transferase beta subunitHaemophilus influenzae43%3e-46180
Post Translational Modification
PTM Type PTM Sub Type Score Modification Site Prosite ID
AcylationN-myristoylation site26-31; 31-36; 59-64; 63-68; 64-69; 132-137; 197-202; 264-269; 287-292; 394-399; 454-459; PS00008
GlycosylationN-glycosylation site48-51; 54-57; PS00001
PhosphorylationCasein kinase II phosphorylation site15-18; 19-22; 110-113; 350-353; 415-418; 432-435; 469-472; PS00006
PhosphorylationProtein kinase C phosphorylation site5-7; 206-208; 265-267; 415-417; 432-434; PS00005
Succinyl-coa:3-ketoacid-coenzyme a transferase-like protein [Q4Q7A2]
Model Information
Template PDB ID2nrcD
Percent Identity45%
Target Region1-494
Template Region1-469
Domain Information
Domains Start End
Active Site Information
Residue Active Site Number Functional Part
Co-Factor
Metal Description
Ligands
CAS number Name Mol. Weight Mol. Formula Smile Notation PDB Reference
Mutational Information
Residue Feature Description
Modeled Protein Template Structure
+----------<<< P R O C H E C K S U M = M A R Y >>>----------+ | = | | /var/www/html/Services/SAVES_3/jobs/3792780/Q4Q7A2.pdb 2.0 494 = residues | | = | *| Ramachandran plot: 92.2% core 7.1% allow 0.5% gener 0.2% = disall | | = | +| All Ramachandrans: 8 labelled residues (out of 492) = | +| Chi1-chi2 plots: 3 labelled residues (out of 256) = | | = | | Main-chain params: 6 better 0 inside 0 worse = | | Side-chain params: 5 better 0 inside 0 worse = | | = | *| Residue properties: Max.deviation: 9.8 Bad contacts: = 1 | *| Bond len/angle: 5.3 Morris et al class: 1 = 1 2 | | = | | G-factors Dihedrals: 0.03 Covalent: -0.16 Overall: = -0.04 | | = | | M/c bond lengths: 98.9% within limits 1.1% highlighted = | | M/c bond angles: 93.6% within limits 6.4% highlighted = | | Planar groups: 100.0% within limits 0.0% highlighted = | | = | = +------------------------------------------------------------------------= ----+ + May be worth investigating further. * Worth investigating further.
Overlapped Structure Procheck Summary
LeishBase: Leishmania Structural Database
Developed and Managed by: Department of Pharmacoinformatics, NIPER S.A.S. Nagar (Mohali)-160062, Punjab (INDIA)