| Adp-ribosylation factor, putative [Q4Q5Y0] | |
|---|---|
| Systematic Name | LmjF.31.2790 [Leishmania major] |
| Gene Name | LMJF_31_2790 |
| Molecular Weight | 20189 Da |
| Protein Sequence Size | 178 |
| Function | |
| Charge | 3 |
| Isoelectric Point | 8.6568 pH |
| Description | Adp-ribosylation factor, putative. |
| Subcellular Location | N.A.[Predict] |
| E. C. Number | N.A. |
| Sequence | >tr|Q4Q5Y0|Q4Q5Y0_LEIMA Adp-ribosylation factor, putative - Leishmania major GGWLSSLLGKKEVRILMVGLDAAGKTTILYKLKLGEVVTTIPTIGFNVETLEYKNLKFTM WDVGGQDKLRPLWRHYYQNTNGIIFVVDSNDRDRMRDARAELEKMLVEDDLRAATLLVFA NKQDLPNAMSTTEVTEKLGLHALRQRNWYIQGCCGTTAQGLYEGLDWLSANIKKSMN |
| DNA Sequence | >LmjF31.2790 |||adp-ribosylation factor, putative|Leishmania major|chr 31|||Manual ATGGGAGGCT GGCTGTCATC GCTACTGGGC AAGAAGGAGG TGCGTATCCT CATGGTCGGTCTTGATGCCG CCGGTAAGAC CACCATTCTG TACAAACTGA AGCTCGGCGA GGTCGTGACCACCATTCCGA CCATCGGGTT TAACGTCGAG ACGCTTGAGT ACAAGAATCT CAAGTTCACCATGTGGGATG TCGGTGGCCA GGACAAGCTT CGCCCGCTGT GGCGCCACTA CTATCAGAACACGAATGGCA TCATTTTCGT GGTCGATAGC AACGATCGCG ATCGCATGCG CGATGCCCGGGCGGAGTTGG AGAAAATGCT TGTTGAGGAC GATCTCCGCG CCGCGACGCT GCTCGTGTTCGCCAACAAGC AGGATTTGCC GAATGCCATG AGCACGACAG AGGTGACGGA GAAGCTTGGCCTGCATGCCC TGCGCCAGCG CAACTGGTAC ATTCAGGGCT GCTGCGGCAC CACCGCTCAGGGTCTCTACG AGGGCCTCGA CTGGCTTTCT GCCAACATCA AGAAGTCCAT GAACTAA |
| Adp-ribosylation factor, putative Q4Q5Y0] | |
|---|---|
| Metabolite Information | intracellular protein transport; protein transport; small GTPase mediated signal transduction |
| Molecular Function | |
| Biochemical Pathway | |
| Regulatory Pathway | |
| KEGG Pathways | K07977 |
| Orthologs | ||||
| Homologs | GI | Percent Identity | Evalue | Score |
| Homo sapiens | ADP-ribosylation factor 3 [Homo sapiens] | 75 | 9e-77 | 282 |
| DEG Information | ||||
| DEG Protein | DEG Organism | Percent Identity | Evalue | Bit Score |
| YPL218w GTP-binding protein of the ARF family | Saccharomyces cerevisiae | 35% | 3e-25 | 108 |
| Post Translational Modification | ||||
| PTM Type | PTM Sub Type | Score | Modification Site | Prosite ID |
| PDOC00017 | ATP/GTP-binding site motif A (P-loop) | 20-27; | PS00017 | |
| Acylation | N-myristoylation site | 2-7; 20-25; 153-158; 161-166; | PS00008 | |
| Amidation | Amidation site | 9-12; | PS00009 | |
| Phosphorylation | Casein kinase II phosphorylation site | 60-63; 131-134; | PS00006 | |
| Phosphorylation | Protein kinase C phosphorylation site | 136-138; | PS00005 | |
| Adp-ribosylation factor, putative [Q4Q5Y0] | ||
|---|---|---|
| Model Information | ||
| Template PDB ID | 1rrgB | |
| Percent Identity | 76% | |
| Target Region | 1-178 | |
| Template Region | 2-177 | |
| Domain Information | ||
|---|---|---|
| Domains | Start | End |
| Active Site Information | ||
|---|---|---|
| Residue | Active Site Number | Functional Part |
| ALA | 23 | Sidechain |
| Co-Factor | |
|---|---|
| Metal | Description |
| Ligands | |||||
|---|---|---|---|---|---|
| CAS number | Name | Mol. Weight | Mol. Formula | Smile Notation | PDB Reference |
| 146-91-8 | GUANOSINE-5'-DIPHOSPHATE | 443.201 | C10 H15 N5 O11 P2 | O=P(O)(O)OP(=O)(O)OCC3OC(n2cnc1c2N=C(N)NC1=O)C(O)C3O | 1rrg |
| 7791-18-6 | MAGNESIUM ION | 24.305 | Mg | [Mg+2] | 1rrg |
| Mutational Information | ||
|---|---|---|
| Residue | Feature | Description |
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| Modeled Protein | Template Structure |
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+----------<<< P R O C H E C K S U M = M A R Y >>>----------+ | = | | /var/www/html/Services/SAVES_3/jobs/2567448/Q4Q5Y0.pdb 2.0 178 = residues | | = | +| Ramachandran plot: 90.5% core 8.9% allow 0.6% gener 0.0% = disall | | = | *| All Ramachandrans: 6 labelled residues (out of 176) = | +| Chi1-chi2 plots: 1 labelled residues (out of 116) = | | = | | Main-chain params: 6 better 0 inside 0 worse = | | Side-chain params: 5 better 0 inside 0 worse = | | = | | Residue properties: Max.deviation: 2.4 Bad contacts: = 0 | +| Bond len/angle: 4.6 Morris et al class: 1 = 1 2 | | = | | G-factors Dihedrals: 0.00 Covalent: -0.18 Overall: = -0.06 | | = | | M/c bond lengths: 99.7% within limits 0.3% highlighted = | | M/c bond angles: 92.6% within limits 7.4% highlighted = | +| Planar groups: 98.4% within limits 1.6% highlighted = | | = | = +------------------------------------------------------------------------= ----+ + May be worth investigating further. * Worth investigating further. |