| Vacuolar sorting-like protein [Q4Q5H7] | |
|---|---|
| Systematic Name | LmjF.32.1050 [Leishmania major] |
| Gene Name | LMJF_32_1050 |
| Molecular Weight | 22298 Da |
| Protein Sequence Size | 204 |
| Function | |
| Charge | -7 |
| Isoelectric Point | 4.9 pH |
| Description | Vacuolar sorting-like protein. |
| Subcellular Location | cytoplasm; membrane[Predict] |
| E. C. Number | N.A. |
| Sequence | >tr|Q4Q5H7|Q4Q5H7_LEIMA Vacuolar sorting-like protein - Leishmania major VLVLVVGDTWVPQRASGVPEVFCKMFSPGRIHKLLITGGVGSKEMYDYLRTIAPEVHCVT SSVDRQWADHMPESVVLTVEGLKLGLIHGHQVPVGDKDSLAAVQRELDVDVLVSGSTHQS KYFEFDSHLFVNPGSLSGADTEYDVNVVPSFMLLDIQDKSVVTFIYQFHPEDETGGGGTA TEDLAAAGMVPGLRIKKKEWAKE |
| DNA Sequence | >LmjF32.1050 |||vacuolar sorting-like protein|Leishmania major|chr 32|||Manual ATGGTTCTCG TGCTCGTCGT GGGTGACACG TGGGTGCCGC AGCGGGCCAG TGGCGTCCCGGAGGTGTTTT GCAAGATGTT CTCGCCTGGC CGCATTCACA AGTTGTTGAT CACGGGTGGCGTCGGCAGCA AGGAAATGTA CGACTACTTG CGCACAATTG CCCCAGAGGT GCACTGTGTGACGAGCAGCG TCGACCGGCA ATGGGCAGAT CACATGCCCG AGAGCGTCGT ACTGACGGTTGAAGGCCTCA AGCTCGGGCT CATTCATGGC CACCAAGTAC CAGTGGGAGA CAAGGACTCGCTCGCGGCCG TGCAGCGGGA GCTGGATGTG GACGTGCTGG TGTCAGGCTC TACACACCAGTCGAAGTACT TCGAGTTTGA TTCCCACCTC TTTGTCAACC CAGGCTCTCT TAGCGGCGCGGACACAGAGT ACGACGTGAA CGTTGTGCCC TCCTTCATGC TGTTGGACAT CCAAGACAAGTCGGTGGTCA CCTTCATTTA CCAGTTTCAC CCGGAGGACG AGACCGGCGG CGGCGGCACCGCTACCGAGG ACTTGGCAGC GGCTGGGATG GTGCCTGGCC TCAGGATCAA GAAGAAGGAATGGGCTAAGG AGTGA |
| Vacuolar sorting-like protein Q4Q5H7] | |
|---|---|
| Metabolite Information | protein transport; vesicle-mediated transport |
| Molecular Function | |
| Biochemical Pathway | |
| Regulatory Pathway | |
| KEGG Pathways | K07095 |
| Orthologs | ||||
| Homologs | GI | Percent Identity | Evalue | Score |
| Homo sapiens | vacuolar protein sorting 29 isoform 1 [Homo sapiens] | 47 | 1e-40 | 162 |
| DEG Information | ||||
| DEG Protein | DEG Organism | Percent Identity | Evalue | Bit Score |
| YHR005c GTP-binding protein alpha subunit of the pheromone pathway | Saccharomyces cerevisiae | 27% | 0.49 | 28.5 |
| Post Translational Modification | ||||
| PTM Type | PTM Sub Type | Score | Modification Site | Prosite ID |
| Acylation | N-myristoylation site | 39-44; 82-87; 86-91; 135-140; 176-181; 177-182; 178-183; 189-194; | PS00008 | |
| Phosphorylation | Casein kinase II phosphorylation site | 62-65; 138-141; 142-145; 180-183; | PS00006 | |
| Sulfation | Tyrosine sulfation site | 137-151; | PS00003 | |
| Vacuolar sorting-like protein [Q4Q5H7] | ||
|---|---|---|
| Model Information | ||
| Template PDB ID | 2r17B | |
| Percent Identity | 47% | |
| Target Region | 1-205 | |
| Template Region | 1-183 | |
| Domain Information | ||
|---|---|---|
| Domains | Start | End |
| Active Site Information | ||
|---|---|---|
| Residue | Active Site Number | Functional Part |
| Co-Factor | |
|---|---|
| Metal | Description |
| Ligands | |||||
|---|---|---|---|---|---|
| CAS number | Name | Mol. Weight | Mol. Formula | Smile Notation | PDB Reference |
| 8013-25-0 | GLYCEROL | 92.094 | C3 H8 O3 | OCC(O)CO | 2r17 |
| Mutational Information | ||
|---|---|---|
| Residue | Feature | Description |
|
|
|
| Modeled Protein | Template Structure |
|
|
+----------<<< P R O C H E C K S U M = M A R Y >>>----------+ | = | | /var/www/html/Services/SAVES_3/jobs/3712353/Q4Q5H7.pdb 2.0 204 = residues | | = | +| Ramachandran plot: 95.4% core 2.9% allow 1.7% gener 0.0% = disall | | = | +| All Ramachandrans: 3 labelled residues (out of 202) = | +| Chi1-chi2 plots: 2 labelled residues (out of 109) = | | = | | Main-chain params: 6 better 0 inside 0 worse = | | Side-chain params: 5 better 0 inside 0 worse = | | = | *| Residue properties: Max.deviation: 2.9 Bad contacts: = 1 | *| Bond len/angle: 5.2 Morris et al class: 1 = 1 3 | +| 1 cis-peptides = | | G-factors Dihedrals: -0.01 Covalent: -0.14 Overall: = -0.06 | | = | | M/c bond lengths: 99.6% within limits 0.4% highlighted = | | M/c bond angles: 94.9% within limits 5.1% highlighted = | | Planar groups: 100.0% within limits 0.0% highlighted = | | = | = +------------------------------------------------------------------------= ----+ + May be worth investigating further. * Worth investigating further. |