| Hypothetical protein [Q4Q530] | |
|---|---|
| Systematic Name | LmjF.32.2450 [Leishmania major] |
| Gene Name | TUT4 |
| Molecular Weight | 39673 Da |
| Protein Sequence Size | 356 |
| Function | |
| Charge | 4 |
| Isoelectric Point | 7.7761 pH |
| Description | Hypothetical protein. |
| Subcellular Location | Mitochondrion[Predict] |
| E. C. Number | N.A. |
| Sequence | >tr|Q4Q530|Q4Q530_LEIMA Hypothetical protein - Leishmania major KGKAGRSIAAISDVRAAVLRFCDEQLSRRLDTQPVAEVHQKVSACVQTVDPAMTPYIFGS TAVLGVHEQGSDVDFVCLSPTDVQDGKGADAVSEVAKGLQSDFLFRLGEVVKREHYLWGI ELVRRTRVPVLRVKGGLGVDGVSFDVTANRRNGVRNSALLRAYFTQCPEARWLSMLVKQW SKKTGLNASVEGGCITSYGWNIMIVYYLLRRRLVTLVPVESCDVADIAPMPPHMPLESLQ QGGQGLADMLMDFVSYYLDEFAPETEVMSLTRAAGETTTEMLSWTKQAEDMARIRGEKIH YRWCIEDPYEYDLNVGRNVTPFKLMLLRKHLERARETALLLLATPPPSATARSVK |
| DNA Sequence | >LmjF32.2450 |||hypothetical protein, conserved|Leishmania major|chr 32|||Manual ATGAAAGGCA AGGCAGGGCG ATCGATCGCC GCGATTAGCG ACGTTCGAGC AGCGGTGTTGCGATTCTGCG ATGAGCAGCT ATCGCGGCGG CTGGACACGC AACCCGTCGC GGAGGTCCATCAGAAGGTCT CCGCGTGCGT GCAGACGGTG GACCCGGCGA TGACCCCCTA CATCTTCGGCTCCACCGCTG TGCTGGGCGT ACACGAGCAG GGCTCTGATG TGGATTTTGT CTGCTTGAGCCCGACGGATG TGCAGGATGG CAAAGGTGCC GATGCTGTCT CGGAGGTAGC GAAAGGATTGCAGTCAGACT TCCTCTTCCG CCTGGGCGAG GTGGTGAAAC GGGAGCATTA CCTGTGGGGTATCGAGCTTG TCCGCCGTAC GCGTGTGCCG GTGCTGCGCG TGAAGGGTGG TCTCGGTGTGGATGGCGTGA GCTTCGACGT GACGGCGAAT CGCCGCAACG GCGTGCGCAA CAGCGCTCTGCTGCGGGCGT ACTTCACCCA GTGTCCCGAG GCGCGCTGGT TGAGCATGCT CGTGAAGCAGTGGAGTAAGA AGACGGGACT GAACGCCTCC GTGGAGGGCG GCTGCATCAC CTCCTATGGCTGGAACATCA TGATCGTCTA CTACCTGCTG CGAAGGAGGC TAGTGACCCT CGTGCCGGTGGAGTCGTGCG ACGTGGCTGA CATCGCCCCG ATGCCACCTC ACATGCCGCT GGAGAGCCTCCAGCAGGGTG GCCAAGGGCT GGCGGACATG CTGATGGACT TTGTGAGCTA CTATCTCGACGAGTTCGCAC CTGAGACGGA GGTGATGAGC CTGACCCGGG CGGCGGGGGA GACGACGACGGAGATGCTCT CGTGGACGAA GCAGGCAGAA GACATGGCCC GGATCCGCGG AGAGAAGATACACTACCGGT GGTGCATCGA GGACCCGTAC GAGTACGACT TGAACGTTGG CCGCAACGTGACTCCCTTTA AGCTCATGCT TCTGCGGAAG CATCTAGAGC GTGCACGGGA GACGGCGCTGCTACTGTTGG CTACACCACC GCCTTCTGCG ACGGCAAGGT CAGTGAAGTG A |
| Hypothetical protein Q4Q530] | |
|---|---|
| Metabolite Information | biological process unknown |
| Molecular Function | |
| Biochemical Pathway | |
| Regulatory Pathway | |
| KEGG Pathways | |
| Orthologs | ||||
| Homologs | GI | Percent Identity | Evalue | Score |
| Homo sapiens | PAP associated domain containing 4 [Homo sapiens] | 22 | 0.000009 | 48 |
| DEG Information | ||||
| DEG Protein | DEG Organism | Percent Identity | Evalue | Bit Score |
| priA Primosomal replication factor Y | Staphylococcus aureus | 38% | 3.1 | 26.9 |
| Post Translational Modification | ||||
| PTM Type | PTM Sub Type | Score | Modification Site | Prosite ID |
| PDOC00595 | Formate--tetrahydrofolate ligase signatures | 188-191; | PS00722 | |
| PDOC00015 | The rule PS00015 has been deleted from the PROSITE database and replaced by the following motif: PS50079 (Bipartite nuclear localization signal profile | 113-129; | PS00015 | |
| Acylation | N-myristoylation site | 154-159; 186-191; 193-198; 194-199; 244-249; | PS00008 | |
| Phosphorylation | Casein kinase II phosphorylation site | 72-75; 80-83; 278-281; | PS00006 | |
| Phosphorylation | Protein kinase C phosphorylation site | 28-30; 182-184; 351-353; 354-356; | PS00005 | |
| Phosphorylation | Tyrosine kinase phosphorylation site | 294-302; 303-310; | PS00007 | |
| Sulfation | Tyrosine sulfation site | 303-317; 305-319; | PS00003 | |
| Hypothetical protein [Q4Q530] | ||
|---|---|---|
| Model Information | ||
| Template PDB ID | 2q0gB | |
| Percent Identity | 52% | |
| Target Region | 1-343 | |
| Template Region | 3-324 | |
| Domain Information | ||
|---|---|---|
| Domains | Start | End |
| Active Site Information | ||
|---|---|---|
| Residue | Active Site Number | Functional Part |
| LYS | 179 | Sidechain |
| Co-Factor | |
|---|---|
| Metal | Description |
| Ligands | |||||
|---|---|---|---|---|---|
| CAS number | Name | Mol. Weight | Mol. Formula | Smile Notation | PDB Reference |
| 16887-00-6 | CHLORIDE ION | 35.453 | Cl | [Cl-] | 2q0g |
| 7791-18-6 | MAGNESIUM ION | 24.305 | Mg | [Mg+2] | 2q0g |
| 550.367 | C18 H23 N4 O14 P | O=C1C=CN(C(=O)N1)C4OC(CO)C(OP(=O)(O)OCC3OC(N2C(=O)NC(=O)C=C2)C(O)C3O)C4O | 2q0g | ||
| Mutational Information | ||
|---|---|---|
| Residue | Feature | Description |
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| Modeled Protein | Template Structure |
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+----------<<< P R O C H E C K S U M = M A R Y >>>----------+ | = | | /var/www/html/Services/SAVES_3/jobs/3727950/Q4Q530.pdb 2.0 343 = residues | | = | +| Ramachandran plot: 92.7% core 7.0% allow 0.3% gener 0.0% = disall | | = | +| All Ramachandrans: 4 labelled residues (out of 341) = | +| Chi1-chi2 plots: 1 labelled residues (out of 196) = | | = | | Main-chain params: 6 better 0 inside 0 worse = | | Side-chain params: 5 better 0 inside 0 worse = | | = | *| Residue properties: Max.deviation: 4.3 Bad contacts: = 0 | *| Bond len/angle: 7.4 Morris et al class: 1 = 1 2 | | = | | G-factors Dihedrals: 0.11 Covalent: -0.16 Overall: = 0.01 | | = | | M/c bond lengths: 99.2% within limits 0.8% highlighted = | | M/c bond angles: 93.1% within limits 6.9% highlighted = | | Planar groups: 100.0% within limits 0.0% highlighted = | | = | = +------------------------------------------------------------------------= ----+ + May be worth investigating further. * Worth investigating further. |