| Small nuclear ribonucleoprotein SmD2 [Q4Q3L7] | |
|---|---|
| Systematic Name | LmjF.33.3190 [Leishmania major] |
| Gene Name | LMJF_33_3190 |
| Molecular Weight | 11779 Da |
| Protein Sequence Size | 103 |
| Function | |
| Charge | 6.5 |
| Isoelectric Point | 10.3 pH |
| Description | Small nuclear ribonucleoprotein SmD2. |
| Subcellular Location | nucleus; ribonucleoprotein complex; small nuclear ribonucleoprotein complex; small nucleolar ribonucleoprotein complex[Predict] |
| E. C. Number | N.A. |
| Sequence | >tr|Q4Q3L7|Q4Q3L7_LEIMA Small nuclear ribonucleoprotein SmD2 - Leishmania major. DSEQPKKVPRTETKTKELLRTTVADGPFSLLDTAMKEKKRVFIQCRNSKALLAHVIAFDK HFNLVLKGVQEITESHGSEQKQRTIENLFLRGESVIFIVKLP |
| DNA Sequence | >LmjF33.3190 |||small nuclear ribonucleoprotein SmD2|Leishmania major|chr 33|||Manual ATGGACTCGG AGCAGCCCAA GAAGGTCCCA AGGACGGAGA CCAAGACGAA AGAGCTGTTGCGTACCACCG TCGCCGACGG CCCCTTCAGC CTCCTAGACA CTGCCATGAA GGAGAAAAAGCGGGTCTTCA TCCAGTGTCG CAACAGCAAG GCGCTTCTGG CACACGTGAT CGCCTTTGACAAGCACTTTA ATCTCGTGCT GAAGGGCGTC CAGGAGATCA CTGAAAGTCA CGGCTCCGAGCAGAAGCAGC GCACCATCGA AAACCTCTTT TTGCGCGGCG AGTCGGTAAT TTTCATCGTGAAACTGCCCT AG |
| Small nuclear ribonucleoprotein SmD2 Q4Q3L7] | |
|---|---|
| Metabolite Information | mRNA processing; nuclear mRNA trans splicing, splice leader addition |
| Molecular Function | |
| Biochemical Pathway | |
| Regulatory Pathway | |
| KEGG Pathways | K04796 |
| Orthologs | ||||
| Homologs | GI | Percent Identity | Evalue | Score |
| Homo sapiens | small nuclear ribonucleoprotein polypeptide D2 [Homo sapiens] | 42 | 0.00000000002 | 64 |
| DEG Information | ||||
| DEG Protein | DEG Organism | Percent Identity | Evalue | Bit Score |
| hemE uroporphyrinogen decarboxylase | Salmonella typhimurium | 37% | 0.48 | 26.2 |
| Post Translational Modification | ||||
| PTM Type | PTM Sub Type | Score | Modification Site | Prosite ID |
| Phosphorylation | Casein kinase II phosphorylation site | 23-26; 30-33; | PS00006 | |
| Small nuclear ribonucleoprotein SmD2 [Q4Q3L7] | ||
|---|---|---|
| Model Information | ||
| Template PDB ID | 1b34B | |
| Percent Identity | 42% | |
| Target Region | 27-103 | |
| Template Region | 27-74 | |
| Domain Information | ||
|---|---|---|
| Domains | Start | End |
| Active Site Information | ||
|---|---|---|
| Residue | Active Site Number | Functional Part |
| Co-Factor | |
|---|---|
| Metal | Description |
| Ligands | |||||
|---|---|---|---|---|---|
| CAS number | Name | Mol. Weight | Mol. Formula | Smile Notation | PDB Reference |
| METHYL PHOSPHONIC ACID ADENOSINE ESTER | 345.248 | C11 H16 N5 O6 P | O=P(O)(OCC3OC(n2cnc1c(ncnc12)N)C(O)C3O)C | 1ibs | |
| 22537-48-0 | CADMIUM ION | 112.411 | Cd | [Cd+2] | 1ibs |
| 14808-79-8 | SULFATE ION | 96.063 | O4 S | [O-]S([O-])(=O)=O | 1ibs |
| Mutational Information | ||
|---|---|---|
| Residue | Feature | Description |
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| Modeled Protein | Template Structure |
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+----------<<< P R O C H E C K S U M = M A R Y >>>----------+ | = | | /var/www/html/Services/SAVES_3/jobs/90539/Q4Q3L7.pdb 2.0 77 = residues | | = | | Ramachandran plot: 91.5% core 8.5% allow 0.0% gener 0.0% = disall | | = | +| All Ramachandrans: 2 labelled residues (out of 75) = | | Chi1-chi2 plots: 0 labelled residues (out of 52) = | | = | | Main-chain params: 6 better 0 inside 0 worse = | | Side-chain params: 5 better 0 inside 0 worse = | | = | *| Residue properties: Max.deviation: 2.3 Bad contacts: = 0 | *| Bond len/angle: 5.1 Morris et al class: 1 = 1 3 | +| 1 cis-peptides = | | G-factors Dihedrals: 0.01 Covalent: -0.22 Overall: = -0.07 | | = | | M/c bond lengths: 98.9% within limits 1.1% highlighted = | | M/c bond angles: 93.0% within limits 7.0% highlighted = | | Planar groups: 100.0% within limits 0.0% highlighted = | | = | = +------------------------------------------------------------------------= ----+ + May be worth investigating further. * Worth investigating further. |