| Clathrin coat assembly protein AP17, putative [Q4Q2W7] | |
|---|---|
| Systematic Name | LmjF.34.2330 [Leishmania major] |
| Gene Name | LMJF_34_2330 |
| Molecular Weight | 16812 Da |
| Protein Sequence Size | 143 |
| Function | |
| Charge | -2 |
| Isoelectric Point | 5.6 pH |
| Description | Clathrin coat assembly protein AP17, putative. |
| Subcellular Location | clathrin vesicle coat[Predict] |
| E. C. Number | N.A. |
| Sequence | >tr|Q4Q2W7|Q4Q2W7_LEIMA Clathrin coat assembly protein AP17, putative - Leishmania major. IHFILLQNRVGKTRLAKFYIPVDDAGQAQIKRQVHVIVNTRDTRATNFVSYESIKLVYRR YAGLFFILGIDQEDNDLMYVELIHLLVEVLDMFFKDVCELDLIFNFHKVFMIIDEMIMGG EIQEVSRPVILNRLQELEISSK |
| DNA Sequence | >LmjF34.2330 |||clathrin coat assembly protein AP17, putative|Leishmania major|chr 34|||Manual ATGATCCACT TTATCCTCTT GCAGAACCGC GTGGGCAAGA CCCGGCTGGC CAAGTTTTACATCCCGGTCG ACGATGCCGG CCAAGCGCAG ATCAAGCGTC AGGTCCACGT TATTGTGAACACACGCGATA CGCGCGCGAC AAATTTTGTG TCGTACGAGA GCATCAAGCT CGTCTACCGCCGCTACGCCG GGCTCTTCTT CATCCTCGGC ATCGACCAGG AGGACAACGA CTTGATGTACGTGGAGCTGA TCCACTTACT TGTCGAGGTG CTGGATATGT TCTTCAAGGA TGTGTGCGAGCTGGACTTGA TCTTCAACTT CCACAAGGTC TTCATGATCA TCGACGAAAT GATCATGGGCGGCGAGATCC AGGAGGTGTC GCGGCCGGTC ATCTTGAACC GGCTACAGGA GCTCGAGATCTCAAGCAAGT AG |
| Clathrin coat assembly protein AP17, putative Q4Q2W7] | |
|---|---|
| Metabolite Information | intracellular protein transport; transport |
| Molecular Function | |
| Biochemical Pathway | |
| Regulatory Pathway | |
| KEGG Pathways | |
| Orthologs | ||||
| Homologs | GI | Percent Identity | Evalue | Score |
| Homo sapiens | adaptor-related protein complex 2, sigma 1 subunit isoform AP17 [Homo sapiens] | 46 | 8e-34 | 139 |
| DEG Information | ||||
| DEG Protein | DEG Organism | Percent Identity | Evalue | Bit Score |
| ispA geranyltranstransferase | Haemophilus influenzae | 38% | 0.34 | 28.1 |
| Post Translational Modification | ||||
| PTM Type | PTM Sub Type | Score | Modification Site | Prosite ID |
| Phosphorylation | Protein kinase C phosphorylation site | 54-56; 141-143; | PS00005 | |
| Clathrin coat assembly protein AP17, putative [Q4Q2W7] | ||
|---|---|---|
| Model Information | ||
| Template PDB ID | 2vglS | |
| Percent Identity | 46% | |
| Target Region | 1-143 | |
| Template Region | 1-142 | |
| Domain Information | ||
|---|---|---|
| Domains | Start | End |
| Active Site Information | ||
|---|---|---|
| Residue | Active Site Number | Functional Part |
| Co-Factor | |
|---|---|
| Metal | Description |
| Ligands | |||||
|---|---|---|---|---|---|
| CAS number | Name | Mol. Weight | Mol. Formula | Smile Notation | PDB Reference |
| INOSITOL HEXAKISPHOSPHATE | 660.035 | C6 H18 O24 P6 | O=P(OC1C(OP(=O)(O)O)C(OP(=O)(O)O)C(OP(=O)(O)O)C(OP(=O)(O)O)C1OP(=O)(O)O)(O)O | 1gw5 | |
| Mutational Information | ||
|---|---|---|
| Residue | Feature | Description |
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| Modeled Protein | Template Structure |
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+----------<<< P R O C H E C K S U M = M A R Y >>>----------+ | = | | /var/www/html/Services/SAVES_3/jobs/125184/Q4Q2W7.pdb 2.0 143 = residues | | = | +| Ramachandran plot: 93.2% core 6.0% allow 0.8% gener 0.0% = disall | | = | +| All Ramachandrans: 3 labelled residues (out of 141) = | | Chi1-chi2 plots: 0 labelled residues (out of 106) = | | = | | Main-chain params: 6 better 0 inside 0 worse = | | Side-chain params: 5 better 0 inside 0 worse = | | = | | Residue properties: Max.deviation: 2.6 Bad contacts: = 2 | +| Bond len/angle: 4.4 Morris et al class: 1 = 1 2 | | = | | G-factors Dihedrals: 0.11 Covalent: -0.08 Overall: = 0.04 | | = | | M/c bond lengths: 99.7% within limits 0.3% highlighted = | | M/c bond angles: 95.3% within limits 4.7% highlighted = | | Planar groups: 100.0% within limits 0.0% highlighted = | | = | = +------------------------------------------------------------------------= ----+ + May be worth investigating further. * Worth investigating further. |