| Ribosomal protein l3, putative [Q4Q2Q6] | |
|---|---|
| Systematic Name | LmjF.32.3130 [Leishmania major] |
| Gene Name | LMJF_32_3130 |
| Molecular Weight | 47487 Da |
| Protein Sequence Size | 419 |
| Function | |
| Charge | 68 |
| Isoelectric Point | 11.6611 pH |
| Description | Ribosomal protein l3, putative. |
| Subcellular Location | cytosolic large ribosomal subunit (sensu Eukaryota); integral to membrane; intracellular; organellar large ribosomal subunit; ribosome[Predict] |
| E. C. Number | N.A. |
| Sequence | >tr|Q4Q2Q6|Q4Q2Q6_LEIMA Ribosomal protein l3, putative - Leishmania major SHCKFEHPRHGHLGFLPRKRSRQIRGRARAFPKDDATQKPHLTSFMVFKAGMTHIVRDVD RPGSKVNKKEVVEPVTILEAPPMVIVGIVGYRQTPVGLKTIGTVWAHHTSVEFRRRYYKN WKQSAQLAFSRQKQFANTKEGKVAEARTLNAFAKKASVIRVIAHTQLRKLRNHRVGVKKA HVQEIQVNGGSVAAKIALAKSLLEKEVRVDSVFQQSEACDVCSVTKGHGTEGVVKRWGVA CLPRKTHRGLRKVACIGAWHPARVMYTVARAGQHGYHHRTQLNKKIYQIGRSVAVEPNQA TTTYDLTAKTITPMGGFVGYGTVRNDYVMLKGSVSGPRRRVMTLRRPMAPQTSRQLKEKI VLKFIDTSSKIGHGRFQTKKEKNQWFGPLKKDRIRREERLRKERAARAVERKAKAAKK |
| DNA Sequence | >LmjF32.3130 |||ribosomal protein l3, putative|Leishmania major|chr 32|||Manual ATGTCTCACT GCAAGTTCGA GCACCCCCGC CACGGCCATC TCGGCTTCCT GCCGCGCAAGCGCTCGCGCC AGATCCGCGG CCGTGCGCGC GCGTTCCCCA AGGACGACGC GACGCAGAAGCCCCACCTGA CGAGCTTCAT GGTGTTCAAG GCCGGTATGA CGCACATTGT GCGTGATGTCGATCGCCCTG GATCGAAGGT GAACAAGAAG GAAGTGGTGG AGCCGGTGAC GATCCTGGAGGCGCCGCCGA TGGTGATTGT CGGCATTGTG GGCTACCGCC AAACGCCGGT TGGCCTGAAGACGATCGGCA CCGTGTGGGC GCACCACACG AGCGTCGAGT TCCGCCGCCG CTACTACAAGAACTGGAAGC AGTCTGCGCA ACTGGCCTTC TCCCGCCAGA AGCAGTTTGC GAACACGAAGGAGGGCAAGG TCGCCGAGGC GCGCACGCTG AACGCGTTCG CGAAGAAGGC GTCCGTCATCCGCGTGATCG CGCACACGCA GCTGCGCAAG CTTCGCAACC ACCGCGTGGG CGTGAAGAAGGCGCACGTGC AGGAGATCCA GGTCAACGGC GGCAGCGTTG CGGCGAAGAT CGCGCTGGCCAAGTCCCTGC TGGAGAAGGA GGTGCGCGTC GACTCCGTGT TCCAGCAGTC CGAGGCGTGCGACGTGTGCT CCGTCACGAA AGGCCACGGT ACGGAGGGCG TGGTGAAGCG CTGGGGCGTTGCCTGCCTGC CACGCAAGAC GCACCGCGGT CTGCGCAAGG TTGCGTGCAT CGGCGCGTGGCACCCTGCCC GCGTCATGTA CACTGTCGCG CGCGCCGGTC AGCACGGTTA CCACCACCGCACGCAGCTGA ACAAGAAGAT CTACCAGATC GGCCGCTCCG TTGCTGTGGA GCCGAACCAGGCGACGACGA CCTACGATCT GACAGCCAAG ACGATCACGC CCATGGGTGG CTTCGTCGGCTACGGTACGG TGCGCAACGA CTACGTGATG CTGAAGGGCT CCGTGTCTGG CCCGCGCCGCCGTGTGATGA CGCTGCGCCG CCCGATGGCG CCGCAGACGT CGCGCCAGCT GAAGGAGAAGATCGTGCTGA AGTTCATCGA CACGAGCTCG AAGATCGGCC ACGGCCGCTT CCAGACGAAGAAGGAGAAGA ACCAGTGGTT CGGCCCGCTC AAGAAGGACC GCATCCGCCG CGAGGAGCGCCTGCGCAAGG AGCGCGCTGC CCGCGCCGTG GAGCGCAAGG CAAAGGCCGC GAAGAAGTAA |
| Ribosomal protein l3, putative Q4Q2Q6] | |
|---|---|
| Metabolite Information | protein biosynthesis |
| Molecular Function | |
| Biochemical Pathway | |
| Regulatory Pathway | |
| KEGG Pathways | K02925 |
| Orthologs | ||||
| Homologs | GI | Percent Identity | Evalue | Score |
| Homo sapiens | ribosomal protein L3 isoform a [Homo sapiens] | 58 | 1e-129 | 459 |
| DEG Information | ||||
| DEG Protein | DEG Organism | Percent Identity | Evalue | Bit Score |
| YOR063w 60S large subunit ribosomal protein L3.e | Saccharomyces cerevisiae | 55% | 1e-124 | 440 |
| Post Translational Modification | ||||
| PTM Type | PTM Sub Type | Score | Modification Site | Prosite ID |
| PDOC00385 | Ribosomal protein L3 signature | 214-237; | PS00474 | |
| PDOC00015 | The rule PS00015 has been deleted from the PROSITE database and replaced by the following motif: PS50079 (Bipartite nuclear localization signal profile | 380-396; | PS00015 | |
| Acylation | N-myristoylation site | 64-69; 103-108; 177-182; 190-195; 191-196; 316-321; 322-327; | PS00008 | |
| Phosphorylation | cAMP- and cGMP-dependent protein kinase phosphorylation site | 19-22; 155-158; | PS00004 | |
| Phosphorylation | Casein kinase II phosphorylation site | 77-80; 110-113; 202-205; 303-306; 379-382; | PS00006 | |
| Phosphorylation | Protein kinase C phosphorylation site | 38-40; 247-249; 308-310; 323-325; 344-346; 353-355; 369-371; 379-381; | PS00005 | |
| Ribosomal protein l3, putative [Q4Q2Q6] | ||
|---|---|---|
| Model Information | ||
| Template PDB ID | 1s1iC | |
| Percent Identity | 55% | |
| Target Region | 8-273 | |
| Template Region | 7-359 | |
| Domain Information | ||
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| Domains | Start | End |
| Active Site Information | ||
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| Residue | Active Site Number | Functional Part |
| Co-Factor | |
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| Metal | Description |
| Ligands | |||||
|---|---|---|---|---|---|
| CAS number | Name | Mol. Weight | Mol. Formula | Smile Notation | PDB Reference |
| Mutational Information | ||
|---|---|---|
| Residue | Feature | Description |
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| Modeled Protein | Template Structure |
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+----------<<< P R O C H E C K S U M = M A R Y >>>----------+ | = | | /var/www/html/Services/SAVES_3/jobs/3965556/Q4Q2Q6.pdb 2.0 366 = residues | | = | *| Ramachandran plot: 67.8% core 25.0% allow 3.8% gener 3.4% = disall | | = | *| All Ramachandrans: 55 labelled residues (out of 364) = | *| Chi1-chi2 plots: 8 labelled residues (out of 202) = | | = | +| Main-chain params: 5 better 0 inside 1 worse = | | Side-chain params: 5 better 0 inside 0 worse = | | = | *| Residue properties: Max.deviation: 19.5 Bad contacts: = 32 | *| Bond len/angle: 13.2 Morris et al class: 2 = 1 3 | *| 7 cis-peptides = | +| G-factors Dihedrals: -0.47 Covalent: -0.86 Overall: = -0.59 | | = | | M/c bond lengths: 96.7% within limits 3.3% highlighted = | *| M/c bond angles: 83.4% within limits 16.6% highlighted 6 off = graph | +| Planar groups: 99.2% within limits 0.8% highlighted 1 off = graph | | = | = +------------------------------------------------------------------------= ----+ + May be worth investigating further. * Worth investigating further. |