| Xylulokinase, putative [Q4Q252] | |
|---|---|
| Systematic Name | LmjF.36.0260 [Leishmania major] |
| Gene Name | LMJF_36_0260 |
| Molecular Weight | 53942 Da |
| Protein Sequence Size | 487 |
| Function | |
| Charge | 11.5 |
| Isoelectric Point | 8.1316 pH |
| Description | Xylulokinase, putative (EC 2.7.1.17). |
| Subcellular Location | N.A.[Predict] |
| E. C. Number | 2.7.1.17 |
| Sequence | >tr|Q4Q252|Q4Q252_LEIMA Xylulokinase, putative (EC 2.7.1.17) - Leishmania major YAGIDIGTSGIKIALMRSDGQIADSASAPLTVSSPHPLWNEQDPDSWWMAINSAMNVLKK RQDMSSVRAIGLSGQMHGATLLDKNHKVLRPCILWCDGRCYRECEELEKAVPKSREITGN LMMPGFTAGKLLWVKKHEPEIFAKVNKVLLPKDYVRFLMTGDFASEMSDSSGSMWMDTGK RDWNDDILRATGLSRANMPKLYEGSEITGKLSADVAKRWNMNCVPVVGGGGDNEAGAVGA GLFKPGQAMLSLGTSGVYFVVSDGFHYNTKEAVHSFCHALPERWHLMSVILSCAVCLEWA AKLTRCRSVDEFVGEAMTAKNFDERPLYFLPHLAGERTPHNNPNAKGVFFGLTSHHSRPE LARAVLEGVSFAMSQGMDAVHRCGVEPSNIALIGGGSRSRFWRQMLADVSGYPMDYCIGS EVGPALGACRLAQIAVEKRPLEELLPCLPLKETHMPDMKKHEQYKKRRVIYDELYKQLKP IMNAKL |
| DNA Sequence | >LmjF36.0260 |||xylulokinase, putative|Leishmania major|chr 36|||Manual ATGTACGCCG GTATTGACAT TGGTACCTCG GGCATCAAGA TTGCCTTGAT GAGGAGTGACGGGCAAATCG CCGACAGTGC CTCTGCCCCC CTGACGGTGT CCAGCCCGCA CCCGCTGTGGAATGAGCAGG ACCCTGACTC GTGGTGGATG GCCATCAATA GCGCCATGAA CGTGCTCAAGAAGCGCCAGG ACATGAGCAG CGTCCGCGCG ATTGGCCTGT CGGGCCAGAT GCACGGTGCCACGCTCCTCG ACAAGAACCA CAAGGTGCTG CGTCCGTGCA TCCTCTGGTG CGACGGCCGCTGCTACCGTG AGTGCGAGGA GCTCGAGAAG GCAGTGCCCA AGTCGCGCGA AATCACCGGTAACCTGATGA TGCCCGGCTT TACAGCTGGT AAGCTTCTGT GGGTCAAGAA GCACGAGCCGGAGATCTTCG CCAAGGTAAA CAAAGTGCTG CTCCCGAAAG ACTACGTCCG CTTCCTCATGACTGGCGACT TTGCCTCTGA GATGTCGGAC TCCTCCGGGT CCATGTGGAT GGACACAGGCAAGCGCGACT GGAATGATGA CATTCTGCGC GCGACCGGGC TTAGCCGCGC CAATATGCCGAAGCTGTATG AGGGGTCGGA GATTACCGGC AAGCTGTCGG CGGACGTGGC GAAGCGCTGGAACATGAACT GCGTGCCAGT GGTGGGCGGT GGCGGCGACA ATGAAGCCGG CGCTGTCGGTGCAGGTCTCT TCAAGCCGGG CCAGGCGATG CTGTCCCTCG GAACGTCGGG CGTGTACTTTGTCGTCTCTG ACGGCTTCCA CTACAACACG AAGGAGGCGG TCCACAGCTT CTGCCACGCGCTTCCGGAGC GCTGGCACCT GATGTCGGTC ATCCTCAGCT GCGCTGTGTG CCTGGAGTGGGCTGCGAAGC TAACAAGGTG CAGGAGCGTC GACGAATTCG TGGGCGAAGC GATGACGGCGAAGAACTTCG ATGAGCGTCC CTTGTACTTC CTGCCCCACC TCGCCGGCGA GCGCACGCCGCACAACAACC CGAACGCGAA GGGCGTCTTC TTTGGCCTCA CCTCCCACCA CAGCCGCCCAGAGCTGGCGC GCGCGGTGCT GGAGGGCGTG AGCTTTGCCA TGTCTCAGGG CATGGACGCCGTGCACCGCT GCGGTGTGGA GCCGAGCAAT ATTGCCCTCA TCGGCGGCGG CTCGCGCAGCCGCTTCTGGC GCCAGATGCT GGCCGATGTC AGCGGCTACC CGATGGACTA CTGCATCGGCTCGGAGGTGG GCCCTGCCCT CGGCGCCTGC CGCCTCGCAC AAATTGCCGT AGAGAAGCGCCCCCTGGAGG AGCTACTGCC TTGCCTGCCG CTGAAGGAGA CTCACATGCC CGACATGAAGAAGCACGAGC AGTACAAGAA ACGCCGCGTG ATCTACGACG AGCTGTACAA GCAGCTGAAACCCATCATGA ACGCCAAGCT GTAA |
| Xylulokinase, putative Q4Q252] | |
|---|---|
| Metabolite Information | carbohydrate metabolism; xylulose metabolism |
| Molecular Function | |
| Biochemical Pathway | |
| Regulatory Pathway | |
| KEGG Pathways | K00854 |
| Orthologs | ||||
| Homologs | GI | Percent Identity | Evalue | Score |
| Homo sapiens | glycerol kinase isoform a [Homo sapiens] | 22 | 3e-19 | 94 |
| DEG Information | ||||
| DEG Protein | DEG Organism | Percent Identity | Evalue | Bit Score |
| lyx L-xylulose kinase | Haemophilus influenzae | 25% | 2e-33 | 137 |
| Post Translational Modification | ||||
| PTM Type | PTM Sub Type | Score | Modification Site | Prosite ID |
| PDOC00408 | FGGY family of carbohydrate kinases signatures | 348-368; | PS00445 | |
| PDOC00408 | FGGY family of carbohydrate kinases signatures | 126-138; | PS00933 | |
| PDOC00299 | Microbodies C-terminal targeting signal | 485-487; | PS00342 | |
| Acylation | N-myristoylation site | 4-9; 11-16; 75-80; 193-198; 205-210; 230-235; 237-242; 348-353; 369-374; 385-390; 396-401; | PS00008 | |
| Amidation | Amidation site | 179-182; | PS00009 | |
| Phosphorylation | Casein kinase II phosphorylation site | 81-84; 309-312; 358-361; | PS00006 | |
| Phosphorylation | Protein kinase C phosphorylation site | 67-69; 179-181; 209-211; 319-321; | PS00005 | |
| Phosphorylation | Tyrosine kinase phosphorylation site | 321-329; 469-476; | PS00007 | |
| Xylulokinase, putative [Q4Q252] | ||
|---|---|---|
| Model Information | ||
| Template PDB ID | 2nlxB | |
| Percent Identity | 56% | |
| Target Region | 1-487 | |
| Template Region | 1-472 | |
| Domain Information | ||
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| Domains | Start | End |
| Active Site Information | ||
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| Residue | Active Site Number | Functional Part |
| Co-Factor | |
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| Metal | Description |
| Ligands | |||||
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| CAS number | Name | Mol. Weight | Mol. Formula | Smile Notation | PDB Reference |
| Mutational Information | ||
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| Residue | Feature | Description |
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| Modeled Protein | Template Structure |
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+----------<<< P R O C H E C K S U M = M A R Y >>>----------+ | = | | /var/www/html/Services/SAVES_3/jobs/185664/Q4Q252.pdb 2.0 487 = residues | | = | +| Ramachandran plot: 89.7% core 9.6% allow 0.7% gener 0.0% = disall | | = | +| All Ramachandrans: 13 labelled residues (out of 485) = | +| Chi1-chi2 plots: 2 labelled residues (out of 282) = | | = | | Main-chain params: 6 better 0 inside 0 worse = | | Side-chain params: 5 better 0 inside 0 worse = | | = | *| Residue properties: Max.deviation: 6.7 Bad contacts: = 8 | *| Bond len/angle: 10.4 Morris et al class: 1 = 1 2 | +| 3 cis-peptides = | | G-factors Dihedrals: 0.01 Covalent: -0.23 Overall: = -0.07 | | = | | M/c bond lengths: 99.1% within limits 0.9% highlighted = | *| M/c bond angles: 93.0% within limits 7.0% highlighted 2 off = graph | | Planar groups: 100.0% within limits 0.0% highlighted = | | = | = +------------------------------------------------------------------------= ----+ + May be worth investigating further. * Worth investigating further. |