| Centrin, putative [Q4Q0E9] | |
|---|---|
| Systematic Name | LmjF.36.6110 [Leishmania major] |
| Gene Name | CETN3 |
| Molecular Weight | 18800 Da |
| Protein Sequence Size | 165 |
| Function | |
| Charge | -13 |
| Isoelectric Point | 4.3 pH |
| Description | Centrin, putative. |
| Subcellular Location | N.A.[Predict] |
| E. C. Number | N.A. |
| Sequence | >tr|Q4Q0E9|Q4Q0E9_LEIMA Centrin, putative - Leishmania major LNTAFSTADGRRLPRDLTDQQKRDIEEAFRVLDVKGVSTITPNDLKVALRALGYEPDKDA VRKLVAEMDRGGVSSNLVLSEFEDVMRQRFFAEDKDDEVDLAFPLFTEGKSEFISLDDLK RVAAEVGEDIPEDVLQEIIRECDVLDRDGRISREEFNKMLKSDK |
| DNA Sequence | >LmjF36.6110 |||centrin, putative|Leishmania major|chr 36|||Manual ATGTTAAACA CCGCCTTCTC CACCGCTGAC GGCCGGCGAC TGCCGCGCGA CTTGACGGACCAGCAGAAGC GGGACATTGA GGAGGCGTTC CGCGTGCTCG ACGTGAAAGG CGTGAGCACCATCACACCAA ACGATCTAAA AGTGGCACTG CGCGCGCTCG GGTACGAACC GGACAAGGATGCGGTGCGAA AGCTTGTGGC GGAGATGGAT CGCGGCGGCG TCTCCAGCAA CCTCGTTCTCAGCGAATTTG AGGACGTCAT GCGCCAGCGC TTCTTTGCCG AGGACAAAGA CGACGAGGTGGACCTTGCCT TCCCGCTGTT CACAGAGGGC AAGTCGGAGT TCATCTCTCT CGATGACCTGAAGCGGGTGG CGGCGGAGGT TGGCGAGGAT ATCCCCGAGG ATGTGCTGCA GGAAATCATTCGCGAGTGCG ATGTGCTCGA TCGCGACGGC CGCATTTCCC GTGAGGAGTT CAACAAGATGTTGAAATCAG ACAAGTGA |
| Centrin, putative Q4Q0E9] | |
|---|---|
| Metabolite Information | biological process unknown |
| Molecular Function | |
| Biochemical Pathway | |
| Regulatory Pathway | |
| KEGG Pathways | |
| Orthologs | ||||
| Homologs | GI | Percent Identity | Evalue | Score |
| Homo sapiens | caltractin [Homo sapiens] | 40 | 9e-28 | 119 |
| DEG Information | ||||
| DEG Protein | DEG Organism | Percent Identity | Evalue | Bit Score |
| YOR257w spindle pole body component, centrin | Saccharomyces cerevisiae | 36% | 1e-18 | 86.3 |
| Post Translational Modification | ||||
| PTM Type | PTM Sub Type | Score | Modification Site | Prosite ID |
| Acylation | N-myristoylation site | 72-77; 73-78; | PS00008 | |
| Amidation | Amidation site | 10-13; | PS00009 | |
| Phosphorylation | Casein kinase II phosphorylation site | 7-10; 42-45; 81-84; 116-119; 153-156; | PS00006 | |
| Phosphorylation | Protein kinase C phosphorylation site | 163-165; | PS00005 | |
| Centrin, putative [Q4Q0E9] | ||
|---|---|---|
| Model Information | ||
| Template PDB ID | 2ggmB | |
| Percent Identity | 40% | |
| Target Region | 18-163 | |
| Template Region | 25-144 | |
| Domain Information | ||
|---|---|---|
| Domains | Start | End |
| Active Site Information | ||
|---|---|---|
| Residue | Active Site Number | Functional Part |
| Co-Factor | |
|---|---|
| Metal | Description |
| Ligands | |||||
|---|---|---|---|---|---|
| CAS number | Name | Mol. Weight | Mol. Formula | Smile Notation | PDB Reference |
| 17787-72-3 | CALCIUM ION | 40.078 | Ca | [Ca+2] | 2ggm |
| Mutational Information | ||
|---|---|---|
| Residue | Feature | Description |
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| Modeled Protein | Template Structure |
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+----------<<< P R O C H E C K S U M = M A R Y >>>----------+ | = | | /var/www/html/Services/SAVES_3/jobs/1657238/Q4Q0E9.pdb 2.0 146 = residues | | = | | Ramachandran plot: 93.2% core 6.8% allow 0.0% gener 0.0% = disall | | = | +| All Ramachandrans: 4 labelled residues (out of 144) = | | Chi1-chi2 plots: 0 labelled residues (out of 99) = | | = | | Main-chain params: 6 better 0 inside 0 worse = | | Side-chain params: 5 better 0 inside 0 worse = | | = | *| Residue properties: Max.deviation: 3.3 Bad contacts: = 1 | *| Bond len/angle: 6.2 Morris et al class: 1 = 1 2 | +| 1 cis-peptides = | | G-factors Dihedrals: 0.22 Covalent: -0.06 Overall: = 0.11 | | = | | M/c bond lengths: 99.7% within limits 0.3% highlighted = | | M/c bond angles: 95.8% within limits 4.2% highlighted = | | Planar groups: 100.0% within limits 0.0% highlighted = | | = | = +------------------------------------------------------------------------= ----+ + May be worth investigating further. * Worth investigating further. |