| Protein Name: | glutathione (P48637) |
|---|---|
| Gene Name: | GSS |
| Description: | |
| PDB ID: | |
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This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Doxorubicin | Toxic Effects On Skin | Doxorubicin depletes reductive capacity@ i e decreased the activity of thioredoxin reductase in the skin@ as well as the content of reduced glutathione both in the skin and blood plasma @which leads to toxic effects of doxorubicin in the skin [ ADR Type 5 ] | Doxorubicin toxicity to the skin: possibility of protection with antioxidants enriched yeast |
| Methotrexate | Enterocolitis | Effect of a glutamine-supplemented enteral diet on methotrexate-induced enterocolitis. [ ADR Type 2 ] | Effect of a glutamine-supplemented enteral diet on methotrexate-induced enterocolitis |
This panel provides information on drug category
| Toxicity | Source |
|---|---|
| Enterocolitis | Effect of a glutamine-supplemented enteral diet on methotrexate-induced enterocolitis |