Registration No.:	PI/2011/XIX/312/P
Name:	Sheenu Abbat
Connect at:	Linkedin
Ph.D. Thesis Title:
Pharmacoinformatics analysis of PfDHFR substrate and inhibitors
Research: 13
Abbat S, Jaladanki CK, Bharatam PV. Exploring PfDHFR reaction surface: A combined molecular dynamics and QM/MM analysis. Journal of Molecular Graphics and Modelling 2019, 87: 76-88.
Angmo S, Tripathi N, Abbat S, Sharma S, Singh SS, Halder A, Yadav K, Shukla G, Sandhir R, Rishi V, Bharatam PV, Yadav H, Singhal NK. Identification of Guanosine 5'-diphosphate as Potential Iron Mobilizer: Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway. Scientific Reports 2017, 7: 40097.
Sharma VK, Abbat S, Bharatam PV. Pharmacoinformatic Study on the Selective Inhibition of the Protozoan Dihydrofolate Reductase Enzymes. Molecular Informatics 2017, 36: Article ID 1600156.
Abbat S and Bharatam PV. Electronic structure and conformational analysis of P218: An antimalarial drug candidate. International Journal of Quantum Chemistry 2016, 116: 1362-1369.
Kumar N, Kumar S, Abbat S, Kumar N, Sondhi SM, Bharatam PV, Roy P, Pruthi V. Ferulic acid amide derivatives as anticancer and antioxidant agents: synthesis, thermal, biological and computational studies. Medicinal Chemistry Research 2016, 25: 1175-1192.
Abbat S, Dhaked DK, Arfeen M, Bharatam PV. Mechanism of the Paal-Knorr reaction: the importance of water mediated hemialcohol pathway. RSC Advances 2015, 5: 88353-88366.
Abbat S, Jain V, Bharatam PV. Origins of the specificity of inhibitor P218 toward wild-type and mutant PfDHFR: a molecular dynamics analysis. Journal of Biomolecular Structure and Dynamics 2015, 33: 1913-1928.
Bharate JB, Abbat S, Bharatam PV, Vishwakarma RA, Bharate SB. CuBr catalyzed aerobic oxidative coupling of 2-aminopyridines with cinnamaldehydes: Direct access to 3-formyl-2-phenyl-imidazo[1,2-a]pyridines. Organic & Biomolecular Chemistry 2015, 13: 7790-7794.
Bharate JB, Abbat S, Sharma R, Bharatam PV, Vishwakarma R, Bharate SB. Cobalt (II) catalyzed C(sp)-H bond functionalization of alkynes with phenyl hydrazines: A facile access to diaryl 1,2-diketones. Organic & Biomolecular Chemistry 2015, 13: 5235-5242.
Sharma R, Abbat S, Bharate JB, Bharate SB, Bharatam PV, Vishwakarma R. Ortho-quinone methides: TFA-mediated generation in water and trapping with lactams and styrenes. Tetrahedron Letters 2015, 56: 4057-4059.
Tandon V, Urvashi, Yadav P, Sur S, Abbat S, Tiwari V, Hewer R, Papathanasopoulos MA, Raja R, Banerjea AC, Verma AK, Kukreti S, Bharatam PV. Design, Synthesis, and Biological Evaluation of 1,2-Dihydroisoquinolines as HIV-1 Integrase Inhibitors. ACS Medicinal Chemistry Letters 2015, 6: 1065-1070.
Arfeen M, Patel DS, Abbat S, Taxak N, Bharatam PV. Importance of cytochromes in cyclization reactions: quantum chemical study on a model reaction of proguanil to cycloguanil. Journal of Computational Chemistry 2014, 35: 2047-2055.
Mudududdla R, Sharma R, Abbat S, Bharatam PV, Vishwakarma RA and Bharate SB. Synthesis of 2-phenylnaphthalenes from styryl-2-methoxybenzenes. Chemical Communications 2014, 50: 12076-12079.