Registration No.:	PI/2010/XVIII/278/P
Name:	Vivek Kumar
Connect at:	Linkedin
Ph.D. Thesis Title:
Computer-Aided Molecular Design of InhA Inhibitors for Tuberculosis
Research: 16
Kumar V, Jhamb SS, Sobhia ME. Cell wall permeability assisted virtual screening to identify potential direct InhA inhibitors of Mycobacterium tuberculosis and their biological evaluation. Journal of Biomolecular Structure and Dynamics 2018, 36: 3274-3290.
Kumar V, Sobhia ME. Molecular dynamics-based investigation of InhA substrate binding loop for diverse biological activity of direct InhA inhibitors. Journal of Biomolecular Structure and Dynamics 2016, 34: 2434-52.
Devasari N, Dora CP, Singh C, Paidi SR, Kumar V, Sobhia ME, Suresh S. Inclusion complex of erlotinib with sulfobutyl ether-β-cyclodextrin: Preparation, characterization, in silico, in vitro and in vivo evaluation. Carbohydrate Polymers 2015, 134: 547-556.
Grover J, Bhatt N, Kumar V, Patel NK, Gondaliya BJ and Sobhia ME. 2,5-Diaryl-1,3,4-oxadiazoles as selective COX-2 inhibitors and anti-inflammatory agents. RSC Advances 2015, 5: 45535-45544.
Iyer P, Bolla J, Kumar V, Gill MS, Sobhia ME. In silico identification of targets for a novel scaffold, 2-thiazolylimino-5-benzylidin-thiazolidin-4-one. Molecular Diversity 2015, 19: 855-70.
Kumar V, Sobhia ME. Molecular Dynamics Assisted Mechanistic Study of Isoniazid-Resistance against Mycobacterium tuberculosis InhA. PLoS One 2015, 10: e0144635.
Singh C, Koduri LVSK, Kumar UA, Bhatt TD, Kumar V, Sobhia ME. Attenuation potential of rifampicin-phospholipid complex in murine hepatotoxicity model. Journal of Drug Delivery Science and Technology 2015, 30: 225-231.
Grover J, Kumar V, Singh V, Bairwa K, Sobhia ME, Jachak SM. Synthesis, biological evaluation, molecular docking and theoretical evaluation of ADMET properties of nepodin and chrysophanol derivatives as potential cyclooxygenase (COX-1, COX-2) inhibitors. European Journal of Medicinal Chemistry 2014, 80: 47-56.
Grover J, Kumar V, Sobhia ME, Jachak SM. Synthesis, biological evaluation and docking analysis of 3-methyl-1-phenylchromeno[4,3-c]pyrazol-4(1H)-ones as potential cyclooxygenase-2 (COX-2) inhibitors. Bioorganic & Medicinal Chemistry Letters 2014, 24: 4638-4642.
Kumar V, Sobhia ME. Insights into the bonding pattern for characterizing the open and closed state of the substrate-binding loop in Mycobacterium tuberculosis InhA. Future Medicinal Chemistry 2014, 6: 605-616.
Kumar V and Sobhia ME. Characterisation of the flexibility of substrate binding loop in the binding of direct InhA inhibitors. International Journal of Computational Biology and Drug Design 2013, 6: 318-342.
Arvind A, Kumar V, Saravanan P and Mohan CG. Homology modeling, molecular dynamics and inhibitor binding study on MurD ligase of Mycobacterium tuberculosis. Interdisciplinary Sciences-Computational Life Sciences 2012, 4: 223-238.
Hymavati, Kumar V and Sobhia ME. Implication of crystal water molecules in inhibitor binding at ALR2 active site. Computational and Mathematical Methods in Medicine 2012, 2012: Article ID 541594.
Gautam R, Jachak SM, Kumar V and Mohan CG. Synthesis, biological evaluation and molecular docking studies of stellatin derivatives as cyclooxygenase (COX-1, COX-2) inhibitors and anti-inflammatory agents. Bioorganic & Medicinal Chemistry Letters 2011, 21: 1612-1616.
Kumar V, Saravanan P, Arvind A and Mohan CG. Identification of hotspot regions of MurB oxidoreductase enzyme using homology modeling, molecular dynamics and molecular docking techniques. Journal of Molecular Modeling 2011, 17: 939-953.
Awale M, Kumar V, Saravanan P and Mohan CG. Homology modeling and atomic level binding study of Leishmania MAPK with inhibitors. Journal of Molecular Modeling 2010, 16: 475-488.