 | Registration No.: | 12PIP350 |
| Name: | Vijay Rathod |
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| Connect at: | Linkedin |
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| Ph.D. Thesis Title: |
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| Computational studies on human pregnane x receptor (hPXR) for the identification of hPXR modulators |
| Research: 6 |
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| Kesharwani SS, Nandekar PP, Pragyan P, Rathod V, Sangamwar AT. Characterization of differences in substrate specificity among CYP1A1, CYP1A2 and CYP1B1: an integrated approach employing molecular docking and molecular dynamics simulations. Journal of Molecular Recognition 2016, 29: 370-90. |
| Nandekar PP, Khomane K, Chaudhary V, Rathod VP, Borkar RM, Bhandi MM, Srinivas R, Sangamwar AT, Guchhait SK, Bansal AK. Identification of leads for antiproliferative activity on MDA-MB-435 human breast cancer cells through pharmacophore and CYP1A1-mediated metabolism. European Journal of Medicinal Chemistry 2016, 115: 82-93. |
| Rathod V, Belekar V, Garg P and Sangamwar AT. Classification of Human Pregnane x Receptor (hPXR) activators and non-activators by Machine learning techniques: A multifaceted Approach. Combinatorial Chemistry & High Throughput Screening 2016, 19: 307-318. |
| Mulik S, Ghosh S, Bhaumik J, Banerjee UC. Biocatalytic synthesis of (S)-Practolol, a selective β-blocker. Biocatalysis 2015, 1: 130-140. |
| Pragyan P, Kesharwani SS, Nandekar PP, Rathod V, Sangamwar AT. Predicting drug metabolism by CYP1A1, CYP1A2, and CYP1B1: insights from MetaSite, molecular docking and quantum chemical calculations. Molecular Diversity 2014, 18: 865-878. |
| Nandekar PP, Tumbi KM, Bansal N, Rathod VP, Labhsetwar LB, Soumya N, Singh S and Sangamwar AT. Chem-bioinformatics and in vitro approaches for candidate optimization: a case study of NSC745689 as a promising antitumor agent. Medicinal Chemistry Research 2013, 22: 3728-3742. |
| Review: 2 |
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| Jain S, Rathod V, Prajapati R, Nandekar PP, Sangamwar AT. Pregnane X Receptor and P-glycoprotein: a connexion for Alzheimer's disease management. Molecular Diversity 2014, 18: 895-909. |
| Rathod V, Jain S, Nandekar PP and Sangamwar AT. Human pregnane X receptor: A novel target for anticancer drug development. Drug Discovery Today 2013, 19: 63-70. |