![](students/12PIP346.jpg) | Registration No.: | 12PIP346 |
Name: | Neha Trivedi |
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Connect at: | Linkedin |
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Ph.D. Thesis Title: |
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Pharmacoinformatics analysis of human topoisomerase IIa: identifying new opportunies in anticancer drug design |
Conference/Poster/News/Proceedings: 1 |
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Sethi R, Tripathi N, Bharatam PV, Roy I. Amino-terminal wild type huntingtin as a protein folding aid-A function unexplored. FEBS Journal 2016, 283: 105. |
Research: 11 |
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Tripathi N, Guchhait SK, Bharatam PV. Pharmacoinformatics analysis of merbarone binding site in human topoisomerase IIα. Journal of Molecular Graphics and Modelling 2019, 86: 1-18. |
Tripathi N, Shaikh N, Bharatam PV, Garg P. HToPred: A Tool for Human Topoisomerase II Inhibitor Prediction. Molecular Informatics 2019, 38: Article ID 1800046. |
Sethi R, Tripathi N, Pallapati AR, Gaikar A, Bharatam PV, Roy I. Does N-terminal huntingtin function as a 'holdase' for inhibiting cellular protein aggregation?. FEBS Journal 2018, 285: 1791-1811. |
Angmo S, Tripathi N, Abbat S, Sharma S, Singh SS, Halder A, Yadav K, Shukla G, Sandhir R, Rishi V, Bharatam PV, Yadav H, Singhal NK. Identification of Guanosine 5'-diphosphate as Potential Iron Mobilizer: Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway. Scientific Reports 2017, 7: 40097. |
Das S, Tripathi N, Preet R, Siddharth S, Nayak A, Bharatam PV, Kundu CN. Quinacrine induces apoptosis in cancer cells by forming a functional bridge between TRAIL-DR5 complex and modulating the mitochondrial intrinsic cascade. Oncotarget 2017, 8: 248-267. |
Das S, Tripathi N, Siddharth S, Nayak A, Nayak D, Sethy C, Bharatam PV, Kundu CN. Etoposide and doxorubicin enhance the sensitivity of triple negative breast cancers through modulation of TRAIL-DR5 axis. Apoptosis 2017, 22: 1205-1224. |
Tripathi N, Bharatam PV, Mori A, Jangra H. Assessing Therapeutic Potential of Molecules: Molecular Property Diagnostic Suite for Tuberculosis (MPDSTB). Journal of Chemical Sciences 2017, 129: 515-531. |
Kaur PK, Tripathi N, Desale J, Neelagiri S, Yadav S, Bharatam PV and Singh S. Mutational and Structural Analysis of Conserved Residues in Ribose-5-Phosphate Isomerase B from Leishmania donovani: Role in Substrate Recognition and Conformational Stability. PLOS One 2016, 11: e0150764. |
Nayak A, Satapathy SR, Das D, Siddharth S, Tripathi N, Bharatam PV, Kundu C. Nanoquinacrine induced apoptosis in cervical cancer stem cells through the inhibition of hedgehog-GLI1 cascade: Role of GLI-1. Scientific Reports 2016, 6: 20600. |
Baviskar AT, Amrutkar SM, Trivedi N, Chaudhary V, Nayak A, Guchhait SK, Banerjee UC, Bharatam PV, Kundu CN. Switch in Site of Inhibition: A Strategy for Structure-Based Discovery of Human Topoisomerase IIa Catalytic Inhibitors. ACS Medicinal Chemistry Letters 2015, 6: 481-485. |
Sanghai N, Jain V, Preet R, Kandekar S, Das S, Trivedi N, Mohaputra P, Priyadarshani G, Kashyap M, Das D, Sathapathy S, Sidharth S, Guchhait SK, Kundu C and Bharatam PV. Combretastatin A-4 Inspired Novel 2-Aryl-3-arylamino-imidazopyridines/pyrazines as Tubulin Polymerization Inhibitors, Antimitotic and Anticancer Agents. MedChemComm 2014, 5: 766-782. |