![](students/12PIP345.jpg) | Registration No.: | 12PIP345 |
Name: | Mahesh Sharma |
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Connect at: | Linkedin |
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Ph.D. Thesis Title: |
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Genome-Scale Metabolic Network Reconstruction of Leishmania Donovani and its simulation for target identification and subsequent drug discovery |
Research: 10 |
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Kumar V, Sharma M, Rakesh BR, Malik CK, Soumya N, Babu NK, Garg P and Singh S. Pyridoxal kinase: A vitamin B6 salvage pathway enzyme from Leishmania donovani. International Journal of Biological Macromolecules 2018, 119: 320-334. |
Shaikh N, Sharma M, Garg P. Selective Fusion of Heterogeneous Classifiers for Predicting Substrates of Membrane Transporters. Journal of Chemical Information and Modeling 2017, 57: 594-607. |
Sharma M, Shaikh N, Yadav S, Singh S, Garg P. A systematic reconstruction and constraint-based analysis of Leishmania donovani metabolic network: identification of potential antileishmanial drug targets. Molecular BioSystems 2017, 13: 955-969. |
Shaikh N, Sharma M and Garg P. An improved approach for predicting drug-target interaction: proteochemometrics to molecular docking. Molecular BioSystems 2016, 12: 1006-1014. |
Swain D, Patel P, Gangam N, Sharma M, Garg P, Srinivas K and Samanthula G. Liquid Chromatographic Method Development for Forced Degradation Products of Dabigatran Etexilate: Characterisation and In Silico Toxicity Evaluation. Chromatographia 2016, 79: 169-178. |
Kalariya PD, Patel PN, Kavya P, Sharma M, Garg P, Srinivas R. Rapid structural characterization of in vivo and in vitro metabolites of tinoridine using UHPLC-QTOF-MS/MS and in silico toxicological screening of its metabolites. Journal of Mass Spectrometry 2015, 50: 1222-1233. |
Kumar R, Sharma M, Shaikh N, Garg P. A comparative study of integrase binding domain of homologous HRP2 and LEDGF/p75 protein: From sequence to structural characterization. Molecular Simulation 2015, 41: 683-690. |
Patel PN, Kalariya PD, Sharma M, Garg P, Talluri MV, Gananadhamu S, Srinivas R. Characterization of forced degradation products of pazopanib hydrochloride by UHPLC-Q-TOF/MS and in silico toxicity prediction. Journal of Mass Spectrometry 2015, 50: 918-928. |
Talluri MVNK, Kalariya PD, Reddy TJ, Sharma M, Garg P and Srinivas R. Characterization of stress degradation products of blonanserin by UPLC-QTOF-Tandem Mass Spectrometry. RSC Advances 2015, 5: 69273-69288. |
Talluri MVNK, Kalariya PD, Reddy TJ, Sharma M, Garg P and Srinivas R. Characterization of stress degradation products of mirabegron using UPLC-QTOF-MS/MS and in silico toxicity predictions of its degradation products. RSC Advances 2015, 5: 31024-31038. |
Review: 1 |
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Sharma M and Garg P. Computational Approaches for Enzyme Functional Class Prediction: A Review. Current Proteomics 2014, 11: 17-22. |