Protein Name: | Vasopressin V1a receptor (P37288) |
---|---|
Gene Name: | AVPR1A |
Description: | Vasopressin V1a receptor (V1aR) (Vascular/hepatic-type arginine vasopressin receptor) (Antidiuretic hormone receptor 1a) (AVPR V1a) |
PDB ID: | |
Protein Family: | |
Protein Category: | Membrane Receptors |
This panel provides drug-protein interaction and their ADRs along with references
Interacting Drugs | Toxicity | Mechanism | Reference |
---|---|---|---|
human insulin | Hypoglycemia | Increase by naloxone of arginine vasopressin and oxytocin responses to insulin-induced hypoglycemia in obese men [ ADR Type 1 ] | Increase by naloxone of arginine vasopressin and oxytocin responses to insulin-induced hypoglycemia in obese men |
Prostaglandin (PG) E1 | Atropine-Antagonized Miosis | The PGEs elicited pronounced@ atropine-antaGOnized miosis and an inhibition of the water diuresis accompanied by some increase in renal excretion of arginine vasopressin (AVP) [ ADR Type 1 ] | Atropine-antaGOnized miosis induced in the GOat by intravenous infusions of prostaglandin E (PGE1 and PGE2) |
Prostaglandin (PG) E1 | Miosis | Endotoxin-induced miosis and stimulation of AVP secretion previously demonstrated in the GOat might well have been secondary to systemic PGE production by intravenous infusions of prostaglandin E (PGE1 and PGE2) [ ADR Type 1 ] | Atropine-antaGOnized miosis induced in the GOat by intravenous infusions of prostaglandin E (PGE1 and PGE2) |
This panel provides information on drug category
Toxicity | Source |
---|