| Protein Name: | Urokinase-type plasminogen activator (P00749) |
|---|---|
| Gene Name: | PLAU |
| Description: | Urokinase-type plasminogen activator precursor (EC 3 4 21 73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B] |
| PDB ID: | 1C5W |
| Protein Family: | |
| Protein Category: | Enzyme |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Dactinomycin | Angiogenesis | OSM stimulated increased mRNA levels of urokinase-plasminogen activator (uPA) and urokinase-plasminogen activator receptor (uPAR) in a time and dose-dependent manner,which supports a role for OSM in modulating the different phases of angiogenesis [ ADR Type 1 ] | Induction of the urokinase plasminogen activator system by oncostatin M promotes endothelial migration |
This panel provides information on drug category
| Toxicity | Source |
|---|