Protein Name: | Tyrosine-protein kinase (Q13882) |
---|---|
Gene Name: | PTK6 |
Description: | Tyrosine-protein kinase 6 (EC 2 7 10 2) (Breast tumor kinase) (Tyrosine-protein kinase BRK) |
PDB ID: | 1RJA |
Protein Family: | |
Protein Category: | Enzyme |
This panel provides drug-protein interaction and their ADRs along with references
Interacting Drugs | Toxicity | Mechanism | Reference |
---|---|---|---|
Cisplatin | Cytotoxicity | c-Abl and p73 are components of a mismatch-repair-dependent apoptosis pathway which contributes to cisplatin-induced cytotoxicity [ ADR Type 2 ] | The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage |
This panel provides information on drug category
Toxicity | Source |
---|