| Protein Name: | T-lymphocyte activation antigen CD80 (P33681) |
|---|---|
| Gene Name: | CD80 |
| Description: | T-lymphocyte activation antigen CD80 precursor (Activation B7-1 antigen) (CTLA-4 counter-receptor B7 1) (B7) (BB1) |
| PDB ID: | 1DR9 |
| Protein Family: | |
| Protein Category: | Surface Antigen |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Melphalan | Expose P815 Tumor Cells To Oxidative Stress | Exposure of P815 tumor cells to melphalan (L-phenylalanine mustard; L-PAM) leads to up-regulation of B7-1 surface expression@which exposes P815 tumor cells to oxidative stress [ ADR Type 2 ] | Mechanism of melphalan-induced B7-1 gene expression in P815 tumor cells |
This panel provides information on drug category
| Toxicity | Source |
|---|