| Protein Name: | Serine/threonine-protein kinase PLK2 (Q9NYY3) |
|---|---|
| Gene Name: | PLK2 |
| Description: | Serine/threonine-protein kinase PLK2 (EC 271121) (Polo-like kinase 1) (PLK-2) (Serine/threonine-protein kinase SNK) (Serum-inducible kinase) |
| PDB ID: | 4I5M |
| Protein Family: | |
| Protein Category: | Enzyme |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Paclitaxel | Mitotic Catastrophe | Silencing of the novel p53 target gene serum inducible kinase (Snk/Plk2) leads to mitotic catastrophe in paclitaxel (taxol)-exposed cells. [ ADR Type 2 ] | Silencing of the novel p53 target gene Snk/Plk2 leads to mitotic catastrophe in paclitaxel (taxol)-exposed cells |
This panel provides information on drug category
| Toxicity | Source |
|---|