| Protein Name: | Renin (P00797) |
|---|---|
| Gene Name: | REN |
| Description: | Renin precursor (EC 342315) (Angiotensinogenase) |
| PDB ID: | 1BBS |
| Protein Family: | |
| Protein Category: | Enzyme |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Neurotensin | Hypotensive | NT produces part of its hypotensive effect in anesthetized rats by reducing the activity of the renin angiotensin system. [ ADR Type 1 ] | Partial blockade of neurotensin-induced hypotension in rats by nephrectomy captopril and saralasin Possible mechanisms |
| Theophylline | Bradycardia | Theophylline increased renin release significantly at a renal perfusion pressure,which leads to the greater effect at low blood pressure. [ ADR Type 1 ] | Conditions for augmentation of renin release by theophylline Scand |
This panel provides information on drug category
| Toxicity | Source |
|---|