| Protein Name: | Cytochrome b5 (Q9V4N3) |
|---|---|
| Gene Name: | CYB5 |
| Description: | Cytochrome b5 |
| PDB ID: | 2I96 |
| Protein Family: | |
| Protein Category: |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Indomethacin | Selective Effect Of A P-Chlorophenyl Moiety | Indomethacin in vitro also caused a loss of cytochrome b5@ NADH-cytochrome b5 reductase@ NADPH-cytochrome c reductase and Epoxide hydrolase activities@ but an activation of UDP-glucuronyltransferase@which leads to selective effect of a p-chlorophenyl moiety [ ADR Type 1 ] | Denaturation of cytochrome P-450 by indomethacin and other non-steroidal anti-inflammatory drugs: evidence for a surfactant mechanism and a selective effect of a p-chlorophenyl moiety |
This panel provides information on drug category
| Toxicity | Source |
|---|