| Protein Name: | NMDA receptor-regulated protein (Q9BXJ9) |
|---|---|
| Gene Name: | NARG1 |
| Description: | NMDA receptor-regulated protein 1 (N-terminal acetyltransferase) (Tubedown-1 protein) (Tbdn100) (Gastric cancer antigen Ga19) |
| PDB ID: | |
| Protein Family: | |
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This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Methionine | Cerebrovascular Disease | Hcy@which is formed by demethylation of methionine@exerts a toxic action on neuronal cells trough the stimulation of N-methyl-D-aspartate (NMDA) receptors@which contribute to the cognitive changes and markedly increased risk of cerebrovascular disease in children and young adults with homocystunuria [ ADR Type 1 ] | Hyperhomocysteinemia: atherothrombosis and neurotoxicity |
| Neomycin | Excitotoxic Activation | Ototoxicity produced by neomycin involves the excitotoxic activation of cochlear NMDA receptors. [ ADR Type 2 ] | Aminoglycoside neurotoxicity involves NMDA receptor activation |
This panel provides information on drug category
| Toxicity | Source |
|---|