Protein Name: | Prostaglandin E2 receptor (Q9BGL8) |
---|---|
Gene Name: | Not Available |
Description: | Prostaglandin E2 receptor, EP1 subtype (Prostanoid EP1 receptor) (PGE receptor, EP1 subtype) |
PDB ID: | |
Protein Family: | |
Protein Category: |
This panel provides drug-protein interaction and their ADRs along with references
Interacting Drugs | Toxicity | Mechanism | Reference |
---|---|---|---|
Acetylsalicylic acid | Inflammation | Inhibition of the vasodilator prostaglandins@ prostaglandin E2 and prostacyclin@ as well as the leukotrienes@ may reduce their inflammatory effects in several disease states. [ ADR Type 1 ] | Prostaglandins and the mechanism of action of anti-inflammatory drugs |
Carbachol | Acth | The involvement of prostaglandins (PGs) generated by constitutive and inducible cyclooxygenase (COX-1 and COX-2) in the carbachol-induced ACTH [ ADR Type 1 ] | Effect of constitutive- and inducible-cyclooxygenase in the carbachol-induced pituitary-adrenocortical response during social stress |
Hydrochlorothiazide | Hypocalciuria | Hydrochlorothiazide-induced hypocalciuria due to inhibition of prostaglandin E2 synthesis [ ADR Type 1 ] | Is hydrochlorothiazide-induced hypocalciuria due to inhibition of prostaglandin E2 synthesis |
This panel provides information on drug category
Toxicity | Source |
---|