| Protein Name: | NF-kappaB (Q96RU7) |
|---|---|
| Gene Name: | TRIB3 |
| Description: | Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible putative kinase) (p65-interacting inhibitor of NF-kappaB) (SINK) |
| PDB ID: | |
| Protein Family: | |
| Protein Category: |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Melphalan | Expose P815 Tumor Cells To Oxidative Stress | L-PAM leads to activation of B7-1 gene expression by activating NF-kappaB via a pathway that involves reactive oxygen species@ because NF-kappaB activation is essential for the L-PAM-induced B7-1 gene expression [ ADR Type 2 ] | Mechanism of melphalan-induced B7-1 gene expression in P815 tumor cells |
This panel provides information on drug category
| Toxicity | Source |
|---|