Protein Name: | NMDA receptor-regulated protein 1 (Q8TCU5) |
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Gene Name: | CYP2D6 |
Description: | Glutamate [NMDA] receptor subunit 3A precursor (N-methyl-D-aspartate receptor subtype NR3A) (NMDAR-L) |
PDB ID: | |
Protein Family: | |
Protein Category: | Ion Channels |
This panel provides drug-protein interaction and their ADRs along with references
Interacting Drugs | Toxicity | Mechanism | Reference |
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interferon gamma | Excitotoxic Mechanisms Of Injury | NO acts directly upon immature neurones but indirectly@ via NMDA receptors@ on more mature neurones@showing a complex interaction between inflammatory and excitotoxic mechanisms of injury in mature neurones [ ADR Type 2 ] | A Different pathways for iNOS-mediated toxicity in vitro dependent on neuronal maturation and NMDA receptor expression |
This panel provides information on drug category
Toxicity | Source |
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