Protein Name: | gamma-aminobutyric acid (GABA) receptors (Q5TZ16) |
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Gene Name: | Not Available |
Description: | Novel protein similar to vertebrate gamma-aminobutyric acid (GABA) receptors |
PDB ID: | |
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This panel provides drug-protein interaction and their ADRs along with references
Interacting Drugs | Toxicity | Mechanism | Reference |
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Dehydrated Alcohol | Alcohol Intoxication | Positive modulators for the GABA(A) receptor (20 mg/kg 3alpha-hydroxy-5alpha-pregnan-20-one and 10-30 mg/kg chlordiazepoxide) and opioid receptor (10 mg/kg morphine) produced significant elevations on Edinger-Westphal c-Fos expression@showing that the Edinger-Westphal nucleus is preferentially sensitive to alcohol intoxication [ ADR Type 1 ] | Alcohol-induced c-Fos expression in the Edinger-Westphal nucleus: pharmacological and signal transduction mechanisms |
This panel provides information on drug category
Toxicity | Source |
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