| Protein Name: | Nuclear respiratory factor 1 (Q16656) |
|---|---|
| Gene Name: | NRF1 |
| Description: | Nuclear respiratory factor 1 (NRF-1) (Alpha palindromic-binding protein) (Alpha-pal) |
| PDB ID: | |
| Protein Family: | |
| Protein Category: |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Zidovudine | Mitochondrial Defects | Aparent compensatory increase in mtTFA mRNA level that could not be attributed to enhanced transcriptional activation mediated by nuclear respiratory factor 1 (NRF-1)@indicating that AZT induces mitochondrial defects primarily in muscles with the highest oxidative capacities (heart and RG). [ ADR Type 2 ] | Zidovudine (AZT) induced alterations in mitochondrial biogenesis in rat striated muscles |
This panel provides information on drug category
| Toxicity | Source |
|---|