| Protein Name: | Prostacyclin synthase (Q16647) |
|---|---|
| Gene Name: | PTGIS |
| Description: | Prostacyclin synthase (EC 5 3 99 4) (Prostaglandin I2 synthase) |
| PDB ID: | 2IAG |
| Protein Family: | |
| Protein Category: | Enzyme |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Nafazatrom | Inactivation Of Phs And Prostacyclin Synthase | Oxygenated derivative of PB@ rather than the parent compound@ which is responsible for the inactivation of PHS and prostacyclin synthase@blocks the effects of the PB and H2O2 treatment [ ADR Type 1 ] | Inactivation of prostaglandin H synthase and prostacyclin synthase by phenylbutazone Requirement for peroxidative metabolism |
This panel provides information on drug category
| Toxicity | Source |
|---|